Document detail
ID

doi:10.1186/s13213-023-01744-5...

Author
Khaledi, Mansoor Poureslamfar, Behnam Alsaab, Hashem O. Tafaghodi, Shahrad Hjazi, Ahmed Singh, Rajesh Alawadi, Ahmed Hussien Alsaalamy, Ali Qasim, Qutaiba A. Sameni, Fatemeh
Langue
en
Editor

BioMed Central

Category

Mycology

Year

2024

listing date

1/10/2024

Keywords
gut microbiota aging inflammatory disease metabolism probiotic gut microbiota
Metrics

Abstract

Background The gut microbiota plays a crucial role in regulating the host’s immune responses during aging, which was characterized by a different abundance of bacteria in several age groups.

Main body Gut microbiota dysbiosis is associated with aging, antibiotic exposure, underlying diseases, infections, hormonal variations, circadian rhythm, and malnutrition, either singularly or in combination.

The appropriate use of prebiotics and probiotics may be able to prevent or reduce this disruption.

Conclusion The current review focuses on the gut microbiota composition across the life cycle, factors affecting gut microbiota changes with aging, and interventions to modulate gut microbiota.

Khaledi, Mansoor,Poureslamfar, Behnam,Alsaab, Hashem O.,Tafaghodi, Shahrad,Hjazi, Ahmed,Singh, Rajesh,Alawadi, Ahmed Hussien,Alsaalamy, Ali,Qasim, Qutaiba A.,Sameni, Fatemeh, 2024, The role of gut microbiota in human metabolism and inflammatory diseases: a focus on elderly individuals, BioMed Central

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