Document detail
ID
oai:pubmedcentral.nih.gov:1001...
Topic
Review ArticleAuthor
Gerth van Wijk, Roy Klimek, Ludger Pfaar, OliverLangue
enEditor
Dustri-Verlag Dr. Karl Feistle
Category
Allergologie Select
Year
2023
listing date
10/10/2023
Keywords
endpoints clinical ait allergen immunotherapyAbstract
110 years after the classical study by Noon, numerous studies have confirmed the efficacy of allergen immunotherapy.
A variety of clinical endpoints have been used in these trials.
This review gives an overview of clinical endpoints for randomized clinical trials on allergen immunotherapy (AIT) in rhinitis and asthma.
In addition, real-life studies have been carried out with the same kind of endpoints.
In general, AIT studies are characterized by a lack of standardized and validated outcome measures.
For allergic rhinoconjunctivitis, digital tools have been developed to monitor patients.
Such tools are particularly useful to obtain real-world evidence for AIT.
Finally, well-accepted outcome measures are available for cost-effectiveness studies.
Gerth van Wijk, Roy,Klimek, Ludger,Pfaar, Oliver, 2023, Clinical endpoints in allergen immunotherapy: State of the art 2022 , Dustri-Verlag Dr. Karl Feistle
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