Implementation of REDCap mobile app in an oral HIV clinical study

BACKGROUND: In Peru, HIV cases are highly concentrated among men who have sex with men (MSM).

Despite the availability of anti-retroviral therapy, people living with HIV (PWH) have higher levels of oral diseases.

Alcohol use disorder (AUD) is significantly present among PWH.

Our overarching goal was to generate foundational evidence on the association of AUD and oral health in MSM with HIV and enhance research capacity for future intersectional research on AUD, oral health and HIV.

Our specific aim was to implement an on-site electronic data collection system through the use of a REDCap Mobile App in a low-middle income country (LMIC) setting.

METHODS: Five validated surveys were utilized to gather data on demographics, medical history, HIV status, alcohol use, HIV stigma, perceived oral health status, and dietary supplement use.

These surveys were developed in REDCap and deployed with the REDCap Mobile App, which was installed on ten iPads across two medical HIV clinics in Lima, Peru.

REDCap app as well as the protocol for data collection were calibrated with feedback from trial participants and clinical research staff to improve clinical efficiency and participant experience.

RESULTS: The mean age of participants (n = 398) was 35.94 ± 9.13y, of which 98.5% identified as male, and 85.7% identified as homosexual.

78.1% of participants binge drank, and 12.3% reported being heavy drinkers.

After pilot testing, significant modifications to the structure and layout of the surveys were performed to improve efficiency and flow.

The app was successfully deployed to replace cumbersome paper records and collected data was directly stored in a REDCap database.

CONCLUSIONS: The REDCap Mobile App was successfully used due to its ability to: (a) capture and store data offline, (b) timely translate between multiple languages on the mobile app interface, and (c) provide user-friendly interface with low associated costs and ample support.

TRIAL REGISTRATION: 1R56DE029639-01.