detalle del documento
IDENTIFICACIÓN

oai:pubmedcentral.nih.gov:9619...

Tema
Review Article
Autor
Malosh, Ryan E McGovern, Ian Monto, Arnold S
Langue
en
Editor

Oxford University Press

Categoría

Oxford University Press Public Health Emergency Collection

Año

2022

fecha de cotización

13/1/2023

Palabras clave
vaccine vaccines influenza
Métrico

Resumen

The 10 years between the last influenza pandemic and start of the severe acute respiratory syndrome coronavirus 2 pandemic have been marked by great advances in our ability to follow influenza occurrence and determine vaccine effectiveness (VE), largely based on widespread use of the polymerase chain reaction assay.

We examine the results, focusing mainly on data from the United States and inactivated vaccines.

Surveillance has expanded, resulting in increased ability to characterize circulating viruses and their impact.

The surveillance has often confirmed previous observations on timing of outbreaks and age groups affected, which can now be examined in greater detail.

Selection of strains for vaccines is now based on enhanced viral characterization using immunologic, virologic, and computational techniques not previously available.

Vaccine coverage has been largely stable, but VE has remained modest and, in some years, very low.

We discuss ways to improve VE based on existing technology while we work toward supraseasonal vaccines.

Malosh, Ryan E,McGovern, Ian,Monto, Arnold S, 2022, Influenza During the 2010–2020 Decade in the United States: Seasonal Outbreaks and Vaccine Interventions, Oxford University Press

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