Document detail
ID

doi:10.1186/s12866-024-03379-1...

Author
Ying, Xue Xu, Gufeng Wang, Huiyun Wang, Yue
Langue
en
Editor

BioMed Central

Category

Mycology

Year

2024

listing date

7/17/2024

Keywords
microbiome endometrial hyperplasia uterus 16s rdna ... ... ... microbiome hyperplasia
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Abstract

Background Endometrial hyperplasia (EH) is a precursor to endometrial cancer, and the role of the microbiome in its development is unclear.

Results The present study investigated the uterine microbiome in patients with benign uterine conditions and endometrial hyperplasia.

A significant structural shift in the uterine microbiome of patients with endometrial hyperplasia compared to those with benign conditions was found.

Delftia , Serratia and Stenotrophomonas were significantly enriched in endometrial hyperplasia samples and associated with the presence of endometrial hyperplasia.

Conclusions The novel finding suggested that increased abundance of Delftia , Serratia and Stenotrophomonas is associated with the presence of endometrial hyperplasia.

Further investigation is needed to determine the value of these microbes as biomarkers for endometrial hyperplasia.

Ying, Xue,Xu, Gufeng,Wang, Huiyun,Wang, Yue, 2024, An altered uterine microbiota with endometrial hyperplasia, BioMed Central

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