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ExploreThe causal influence of sarcopenia on cardiometabolic disease and Alzheimer's disease and whether and to what extent insulin resistance plays a mediating role therein were unclear. We performed two‐st...
strength grip effect associations alm [1 causal insulin resistance cardiometabolic traits sarcopenia‐related walking pace alzheimer disease Read moreAutomated diagnosis of Alzheimer Disease(AD) from brain imaging, such as magnetic resonance imaging (MRI), has become increasingly important and has attracted the community to contribute many deep l...
model 2d introduce perspective alzheimer diagnosis adapt 3d Read moreGenerative approaches for cross-modality transformation have recently gained significant attention in neuroimaging. While most previous work has focused on case-control data, the application of gene...
networks alzheimer generative Read moreIL-3 is a hemopoietic growth factor that usually targets blood cell precursors; IL-3R is a cytokine receptor that binds to IL-3. However, IL-3 takes on a different role in the context of glial cells...
alzheimer Read moreBrain-related diseases are more sensitive than other diseases due to several factors, including the complexity of surgical procedures, high costs, and other challenges. Alzheimer's disease is a comm...
mri science disease model alzheimer computer hybrid Read moreSemantic fluency tests have been widely used as a screening test for dementia of Alzheimer type. However, few studies have explored the application of semantic fluency tests in Mandarin Chinese speake...
category scores test participants adults alzheimer fluency Read moreThe amyloid-β (Aβ) peptides, which accumulate in amyloid plaques, are formed by canonical cleavages of the amyloid precursor protein (APP) by β- and γ-secretases. Under physiological co...
contribution mice degradation peptide activity biology souris presence exprimant endosomes présence ηctf avons aβ ainsi sa c99 precursor novel fragments précurseur peptides localization plaques ad ma fragment aηα alzheimer aηβ Read moreThis study aimed to develop new equations to estimate cardiorespiratory fitness specifically for older adults and, secondly, to analyze the associations of cardiorespiratory fitness, both objectively ...
alzheimer cognitive impairment physical fitness aerobic capacity aging adults associated tests measured objectively set cardiorespiratory estimated cognitive Read moreWe present our submission to the ICASSP-SPGC-2023 ADReSS-M Challenge Task, which aims to investigate which acoustic features can be generalized and transferred across languages for Alzheimer's Disea...
detection method science alzheimer disease features Read moreAPOE ^ ε4 is the major genetic risk factor for sporadic Alzheimer’s disease (AD). Although APOE ^ ε4 is known to promote Aβ pathology, recent data also support an effect of APOE polymorphism on phos...
alzheimer tau apoe interactome proteomics neuropathology vs pathology ptau proteins ε4 ad ^ε3/ε3 ^ ε4/ε4 Read moreAlzheimer's Disease (AD) is primarily an irreversible neurodegenerative disorder affecting millions of individuals today. The prognosis of the disease solely depends on treating symptoms as they ari...
structural disease alzheimer Read moreAutomated diagnosis of Alzheimer Disease(AD) from brain imaging, such as magnetic resonance imaging (MRI), has become increasingly important and has attracted the community to contribute many deep l...
model 2d introduce perspective alzheimer diagnosis adapt 3d Read moreAlzheimer's Disease is a devastating neurological disorder that is increasingly affecting the elderly population. Early and accurate detection of Alzheimer's is crucial for providing effective treat...
mri detection alzheimer disease Read moreInternational audience; The link between Alzheimer's disease (AD) and network hypersynchrony-manifesting as epileptic activities-received considerable attention in the past decade. Howev...
alzheimer model noradrenergic transmission cycle tg2576 disease Read moreDisinhibition during early stages of Alzheimer's disease is postulated to cause network dysfunction and hyperexcitability leading to cognitive deficits. However, the underlying molecular mechanism rem...
chloride treatment decline alzheimer kcc2 cognitive Read moreInsoluble fibrillar tau, the primary constituent of neurofibrillary tangles, has traditionally been thought to be the biologically active, toxic form of tau mediating neurodegeneration in Alzheimer’s ...
alzheimer tau seeding spreading microglia propagation oligomeric compared seeding tau Read moreNearly fifty million older people suffer from neurodegenerative diseases, including Alzheimer (AD) and Parkinson (PD) disease, a global burden expected to triple by 2050. Such an imminent “neurologica...
diseases alzheimer parkinson drugs protein Read moreInternational audience; Alzheimer's disease and related dementia (ADRD) are characterized by multiple and progressive anatomo-clinical changes including accumulation of abnormal proteins...
dementia alzheimer csf markers sequence disease cognitive latent time clinical progression Read moreBrain-related diseases are more sensitive than other diseases due to several factors, including the complexity of surgical procedures, high costs, and other challenges. Alzheimer's disease is a comm...
mri science disease model alzheimer computer hybrid Read moreAn interpretable machine learning (ML) framework is introduced to enhance the diagnosis of Mild Cognitive Impairment (MCI) and Alzheimer's disease (AD) by ensuring robustness of the ML models' inter...
interpretability diagnosis alzheimer disease machine Read moreBackground A positive effect of the effect of a 3-month oral spermidine intake on memory performance has already been demonstrated. The continuation of this study aimed to examine whether there could ...
alzheimer nutrition biogen amines memory perfomance cerad-plus memory results performance positive effect Read moreAlzheimer's disease (AD) is the leading cause of dementia, and its early detection is crucial for effective intervention, yet current diagnostic methods often fall short in sensitivity and specifici...
features alzheimer disease learning Read moreAlzheimer's disease is a common cognitive disorder in the elderly. Early and accurate diagnosis of Alzheimer's disease (AD) has a major impact on the progress of research on dementia. At present, re...
loss alzheimer disease Read moreBrain development and maturation leads to grey matter networks that can be measured using magnetic resonance imaging. Network integrity is an indicator of information processing capacity which decline...
alzheimer changes disease axonal integrity loss Read moreFinding effective disease‐modifying treatment for Alzheimer's disease remains challenging due to an array of factors contributing to the loss of neural function. The current study demonstrates a new s...
nanoparticles alzheimer treatment disease Read moreBackground Plasma exchange (PE) is used to treat a range of neurological disorders. Based on results demonstrated in Alzheimer’s disease, we theorized that PE with albumin replacement (PE-A) might alt...
amyotrophic lateral sclerosis plasma exchange albumin cognitive function motor dysfunction lateral amyotrophic expected als sclerosis plasma disease slope treatment pe-a progression Read moreAmyotrophic lateral sclerosis (ALS) is an untreatable and clinically heterogeneous condition primarily affecting motor neurons. The ongoing quest for reliable biomarkers that mirror the disease status...
amyotrophic lateral sclerosis cytokines short chain fatty acids ttv virome metabolism microbiome research patient Read moreBackground Among clinicians and researchers, it is common knowledge that, in ALS, cognitive and behavioral involvement within the spectrum of frontotemporal degenerations (FTDs) begun to be regarded a...
amyotrophic lateral sclerosis frontotemporal degeneration neuropsychology century changes involvement Read moreBackground We investigated the phenotypes and genotypes of a cohort of ‘long-surviving’ individuals with motor neuron disease (MND) to identify potential targets for prognostication. Methods Patients ...
motor neuron disease amyotrophic lateral sclerosis survival genetics survival diagnosis pathogenic diagnostic variant mnd Read moreThe stimulator of interferon genes (STING) pathway has been implicated in neurodegenerative diseases, including Parkinson’s disease and amyotrophic lateral sclerosis (ALS). While prior studies have fo...
motor neuron disease amyotrophic lateral sclerosis dna damage neuroinflammation sting central neurons immune signaling motor cortical activation neurons Read moreObjective To characterize the participant demographics in the Pooled Resource Open-Access ALS Clinical Trials (PRO-ACT) database compared with the web-portal National Amyotrophic Lateral Sclerosis (AL...
amyotrophic lateral sclerosis national als registry pro-act clinical trials demography disparity onset trials enrollees demographics clinical compared als age pro-act Read moreObjective There is increasing evidence that amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease impacting large-scale brain networks. However, it is still unclear which stru...
amyotrophic lateral sclerosis white matter dti network connectomics machine learning psychoradiology = 0 healthy using motor = 2 structural disease als patients baseline rate Read moreProtein homeostasis, or proteostasis, is essential for cell function and viability. Unwanted, damaged, misfolded and aggregated proteins are degraded by the ubiquitin–proteasome system (UPS) and the a...
proteostasis proteasome autophagy alzheimer’s disease huntington’s disease parkinson’s disease amyotrophic lateral sclerosis aging cancer protein Read moreBackground There is an unmet need in amyotrophic lateral sclerosis (ALS) to provide specific biomarkers for the disease. Due to their easy availability, we aimed to investigate whether routine blood p...
amyotrophic lateral sclerosis blood biomarkers survival correlated chloride lmn = 0 als clinical ci 95% 0 [hr Read moreBackground Plasma exchange (PE) is used to treat a range of neurological disorders. Based on results demonstrated in Alzheimer’s disease, we theorized that PE with albumin replacement (PE-A) might alt...
amyotrophic lateral sclerosis plasma exchange albumin cognitive function motor dysfunction lateral amyotrophic expected als sclerosis plasma disease slope treatment pe-a progression Read moreBackground Recent evidence points toward a role of the small ubiquitin-like modifier (SUMO) system, including SUMO4, in protecting from stress insults and neurodegeneration, such as the progressive mo...
amyotrophic lateral sclerosis genetic risk head trauma cancer sumoylation stress granules mrna dynamics significantly carrier protein patients variant stress Read moreObjective Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder associated with progressive loss of motor neurons. It is a growing and underestimated disease, prompting this epidem...
amyotrophic lateral sclerosis epidemiology registry clinical disease progression egypt median egyptian alsfrs-r iqr als Read moreThe stimulator of interferon genes (STING) pathway has been implicated in neurodegenerative diseases, including Parkinson’s disease and amyotrophic lateral sclerosis (ALS). While prior studies have fo...
motor neuron disease amyotrophic lateral sclerosis dna damage neuroinflammation sting central neurons immune signaling motor cortical activation neurons Read moreBackground and objectives Primary lateral sclerosis (PLS) is a motor neuron disease characterised by loss of the upper motor neurons. Most patients present with slowly progressive spasticity of the le...
primary lateral sclerosis amyotrophic lateral sclerosis hereditary spastic paraplegia genetics resulted pathogenic criteria als c9orf72 sclerosis lateral pls variants patients Read moreBiallelic pathogenic repeat expansions in RFC1 were recently identified as molecular origin of cerebellar ataxia, neuropathy, vestibular areflexia syndrome (CANVAS) as well as of one of the most commo...
repeat analysis oxford nanopore sequencing amyotrophic lateral sclerosis rfc1 mnd motor neuron disease additional clinical repeat mnd expansions rfc1 Read moreAmyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by selective, early degeneration of motor neurons in the brain and spinal cord. Motor neurons have long axo...
cytoskeleton neurofilament mitochondria amyotrophic lateral sclerosis neurodegeneration axonal transport gut microbiome neurons mitochondrial cytoskeletal Read moreA central event in the pathogenesis of motor neuron disease (MND) is the loss of neuromuscular junctions (NMJs), yet the mechanisms that lead to this event in MND remain to be fully elucidated. Mainte...
amyotrophic lateral sclerosis als neuromuscular junction musk agrin motor neurons acetylcholine receptors patients muscle mnd Read moreLipids, defined by low solubility in water and high solubility in nonpolar solvents, can be classified into fatty acids, glycerolipids, glycerophospholipids, sphingolipids, and sterols. Lipids not onl...
amyotrophic lateral sclerosis sphingolipids triglycerides phospholipids cholesterol esters fatty acids ceramides arachidonic acid lysophosphatidylcholine eicosanoids als lipids Read moreObjectives The aim of this study was to assess and compare the diagnostic utility of a new diagnostic criteria for amyotrophic lateral sclerosis (ALS), abbreviated as the ‘Gold Coast Criteria’, with t...
amyotrophic lateral sclerosis diagnostic criteria gold coast sensitivity reec diagnostic patients gold sensitivity Read moreBackground A single cycle (two repeated treatments) with intrathecal autologous bone marrow-derived mesenchymal stem cells (BM-MSCs, 26-day interval) showed safety and provided therapeutic benefit las...
lenzumestrocel amyotrophic lateral sclerosis bone marrow-derived mesenchymal st... phase iii patients iii randomized phase control single-cycle injections trial protocol efficacy alsummit study safety months Read more[Objective] Few studies have comprehensively investigated the non-motor symptoms of amyotrophic lateral sclerosis (ALS). We aimed to investigate this aspect of ALS. [Methods] We held a nationwide webi...
amyotrophic lateral sclerosis non-motor symptoms quality of life fatigue pain amyotrophic sclerosis lateral common score respondents patients als pain fatigue Read moreThe most common genetic cause of familial and sporadic amyotrophic lateral sclerosis (ALS) is a GGGGCC hexanucleotide repeat expansion (HRE) in the C9orf72 gene. While direct molecular hallmarks of th...
c9orf72 nuclear morphology nucleocytoplasmic transport nuclear pore complex lamin b1 nuclear envelope amyotrophic lateral sclerosis frontotemporal dementia invaginations morphology repeat nuclear lamina hre Read moreAmyotrophic lateral sclerosis (ALS) is the most common subtype of motor neuron disease (MND). The current gold-standard measure of progression is the ALS Functional Rating Scale—Revised (ALS-FRS(R)), ...
amyotrophic lateral sclerosis motor neuron disease devices sensors clinical trials technology function evaluate mnd included motor progression studies Read moreBackground People with amyotrophic lateral sclerosis (ALS) are at high risk for severe outcomes from Covid-19 infection. Researchers exploring ALS and Covid-19 have focused primarily on system respons...
amyotrophic lateral sclerosis covid 19 pandemics emergency planning protective motivation theory patients family caregivers information als participants coping people costs health covid-19 pandemic care Read moreAmyotrophic lateral sclerosis (ALS) is a rapidly progressive and fatal neurodegenerative disorder, characterized by selective loss of motor neurons (MNs). A number of causative genetic mutations under...
amyotrophic lateral sclerosis fus lipid defects mam disruption er stress mitochondrial dysfunction ca^2+ er cells mam opcs mutant als Read moreDiabesity is a condition where an individual has both diabetes and obesity, which can lead to severe complications including cardiovascular disease, a leading cause of mortality. Recently, cancer has ...
stress diabetes mellitus obesity cancer non-communicable chronic disease stress diabetes obesity patients cause cancer Read moreThe accurate diagnosis of pathological subtypes of lung cancer is of paramount importance for follow-up treatments and prognosis managements. Assessment methods utilizing deep learning technologies ...
pathological multi-modality learning model cancer lung ct Read moreHuman papillomaviruses (HPV) are a major cause of malignancy, contributing to ~5% of all human cancers worldwide, including most cervical cancer cases and a growing number of anogenital and oral cance...
proliferation survival expression lasp1 cancers demonstrate cervical cancer Read moreBACKGROUND: Nowadays, due to various inherent properties, graphene-based nanoparticles are widely used in drug delivery research. On the other hand, folate receptors are highly expressed on the surfac...
ht-29 cancer nanoparticles cells carrier go-alb-cur-fa-5fu Read moreBackground Chromobox protein homolog 7 (CBX7), a member of the Polycomb repressor complex, is a potent epigenetic regulator and gene silencer. Our group has previously reported that CBX7 functions as ...
progression adipose-derived exosomal cells mir-421 cancer cbx7 Read moreThe tumor microenvironment includes a complex network of immune T-cell subsets that play important roles in colorectal cancer (CRC) progression and are key elements of CRC immunotherapy. T cells devel...
colorectal cancer tumor immune microenvironment t cell monoclonal antibody car-t tumor cancer colorectal Read moreAccurate prediction of the likelihood of recurrence is important in the selection of postoperative treatment for patients with early-stage breast cancer. In this study, we investigated whether deep ...
breast images recurrence predicting cancer 0 Read moreBACKGROUND: The immunity of patients with lung cancer decreases after treatment; thus, they are easily infected with pathogenic bacteria that causes pulmonary infections. Understanding the distributio...
using meta-analysis gram-negative treatment prevalence distribution pulmonary infections lung cancer infection patients chinese bacteria Read moreAim The present study aimed to investigate healthcare professionals’ perceptions and experiences in caring for cervical cancer patients. The present study was also designed to assess the healthcare pr...
cervical cancer patient’s care nursing care qualitative study healthcare professionals hpv vaccination treatment modalities healthcare knowledge patients treatment participants 0001 p < 0 cancer age cervical study nurses Read moreBACKGROUND: Patient navigation is an evidence-based intervention that reduces cancer health disparities by directly addressing the barriers to care for underserved patients with cancer. Variability in...
framework center 205 programs settings cancer navigation patient implementation 001 p < care re-aim analyses community-focused intervention Read moreBackground Dysregulation in histone acetylation, a significant epigenetic alteration closely associated with major pathologies including cancer, promotes tumorigenesis, inactivating tumor-suppressor g...
amp-activated protein kinase (ampk... h3k9ac cervical cancer pcaf histone acetylation pcaf growth acetylation ampk activation cervical h3k9 cancer Read moreA combined treatment approach that targets both skin tumor cells and macrophages prevents tumor growth in malignant melanoma and squamous cell carcinoma. Malignant melanoma is the most aggressive and ...
tumour scc cancer skin melanoma atx rhoa tumours Read moreBackground Long-non-coding RNA PVT1 (lncRNA PVT1) can be used as an oncogenic regulatory non-coding RNA (ncRNA) for many cancers. However, its function and mechanism in breast cancer (BRCA) are still ...
breast cancer lncrna pvt1 mir-145-5p glycolysis rna genes proliferation expression related overexpression pvt1 cancer breast cells cell mir-145-5p Read moreMachine learning (ML) approaches have been used to develop highly accurate and efficient applications in many fields including bio-medical science. However, even with advanced ML techniques, cancer ...
model learning 2% expression fuzzy selection gene cancer Read moreProstate cancer is a major disease that threatens men’s health. Its rapid progression, easy metastasis, and late castration resistance have brought obstacles to treatment. It is necessary to find new ...
cancer ferroptosis Read moreThe female pelvis has a complex anatomy, and benign adnexal diseases can present as malignant ovarian masses clinically and radiologically. Between 1 June 2011 and 28 September 2022, we included in th...
ovarian cancer pelvic inflammatory disease adnexal masses tumor markers surgical cancer months masses pelvic disease inflammatory adnexal Read moreBackground Whether cytochrome P450 24A1 (CYP24A1) polymorphism is associated with cancer susceptibility, the individual study results are still controversial. Therefore, we performed a comprehensive s...
cyp24a1 polymorphism cancer meta-analysis rs6068816 rs4809957 breast rs4809960 tc+cc gg aa cyp24a1 polymorphisms vs =0 tt risk cancer results 0 cc susceptibility polymorphism Read moreBackground This study aimed to investigate the trends of aggressive care at the end-of-life (EoL) for patients with advanced cancer in Korea and to identify factors affecting such care analyzing natio...
aggressiveness end-of-life care advanced cancer hospice nationwide < 0 patients 05 cancer korea aggressive 2018 2012 care eol Read moreBACKGROUND: Activation and regulation of androgen receptor (AR) signaling and the DNA damage response impact the prostate cancer (PCa) treatment modalities of androgen deprivation therapy (ADT) and ra...
prostate genomic ar hssb1 response cancer androgen dna Read morePurpose Pegylated liposomal doxorubicin (PLD)-induced hand-foot syndrome (HFS) frequently lowers the quality of life of ovarian cancer patients. Wrist and ankle cooling, having a limited preventive ef...
pegylated liposomal doxorubicin hand-foot syndrome oral dexamethasone regional cooling primary prophylaxis dose cancer ovarian regional study Read more[Image: see text] Extremely short half-life therapeutic molecule nitric oxide (NO) plays significant roles in the functioning of various physiological and pathological processes in the human body, whe...
cells nanoparticles cancer dox Read moreObjective: To investigate the effects of electroacupuncture pre-stimulation on perioperative neurocognitive disorders (PNDs) in patients undergoing colon cancer surgery. Methods: A total of 80 elderly...
surgery pnds undergoing significantly compared protein s100β effects dazhui baihui treatment patients pre-stimulation scores adl sas colon mmse cancer electroacupuncture Read moreObjective To investigate the effect of interferon-γ (IFN-γ) on the immune microenvironment and the polarity of tumor-associated macrophages (TAMs) in stage IA non-small cell lung cancer (NSCLC) and it...
non-small cell lung cancer ifn-γ ido1 immune microenvironment macrophage immune ki-67 lung effect downregulated upregulated proliferation reduced bax bcl-2 c-caspase non-small ifn-γ nsclc stage il-6 microenvironment viability il-13 cancer tnf-α ia il-10 ido1 expression cells increased tams cell tumor decreased Read morePurpose [^18F]-FDG PET/CT and brain MRI are common approaches to detect metastasis in patients of lung cancer. Current guidelines for the use of PET/CT and MRI in clinical T1-category lung cancer lack...
clinical t1-category lung cancer pet/ct brain mri metastasis cancer lung os cut-off pet/ct metastasis 0 hr 001 patients solid Read moreBACKGROUND: Acute tumour embolism to the popliteal artery resulting in limb-threatening ischemia is a rare complication of neoplastic disease. Generally, tumors embolize to the pulmonary circulation v...
limb resulting lung cancer embolization left Read moreRecent studies construct deblurred neural radiance fields (DeRF) using dozens of blurry images, which are not practical scenarios if only a limited number of blurry images are available. This paper ...
sparse images blurry derf Read moreGiven a graph $G=(V,E)$, a function $f:V\to \{0,1,2\}$ is said to be a \emph{Roman Dominating function} if for every $v\in V$ with $f(v)=0$, there exists a vertex $u\in N(v)$ such that $f(u)=2$. A R...
dominating $f domination $ graphs Read moreLarge language models (LLMs) have greatly impacted the natural language processing (NLP) field, particularly for the English language. These models have demonstrated capabilities in understanding an...
english model arabic dataset nlp models language Read moreIn the online knapsack problem, the goal is to pack items arriving online with different values and weights into a capacity-limited knapsack to maximize the total value of the accepted items. We stu...
items computer science prediction value knapsack predictions Read moreGraph contrastive learning (GCL) has recently emerged as a new concept which allows for capitalizing on the strengths of graph neural networks (GNNs) to learn rich representations in a wide variety ...
gcl persistence learning topological extended Read moreMulti-task dense scene understanding, which learns a model for multiple dense prediction tasks, has a wide range of application scenarios. Modeling long-range dependency and enhancing cross-task int...
scene understanding computer mamba multi-task dense Read moreReinforcement Learning from Human Feedback (RLHF) facilitates the alignment of large language models (LLMs) with human preferences, thereby enhancing the quality of responses generated. A critical c...
reward collected comprehensive human collection data Read moreSocial media plays a central role in shaping public opinion and behavior, yet performing experiments on these platforms and, in particular, on feed algorithms is becoming increasingly challenging. T...
field re-ranking experiments social Read moreHyper-spectral imaging has recently gained increasing attention for use in different applications, including agricultural investigation, ground tracking, remote sensing and many other. However, the ...
data computer camera Read moreTask-specific functional MRI (fMRI) images provide excellent modalities for studying the neuronal basis of cognitive processes. We use fMRI data to formulate and solve the problem of deconvolving ta...
neuronal basis task-specific canonical networks Read moreThe conditional diffusion model has been demonstrated as an efficient tool for learning robot policies, owing to its advancement to accurately model the conditional distribution of policies. The int...
model distribution ldp diverse navigation data conditional robot local Read moreWe introduce MelodyFlow, an efficient text-controllable high-fidelity music generation and editing model. It operates on continuous latent representations from a low frame rate 48 kHz stereo variati...
inversion latent music Read moreDeep learning has been impressively successful in the last decade in predicting human head poses from monocular images. However, for in-the-wild inputs the research community relies predominantly on...
estimation Read moreContinuum and soft robots can positively impact diverse sectors, from biomedical applications to marine and space exploration, thanks to their potential to adaptively interact with unstructured envi...
soft rod models control continuum Read moreMulti-variate time series forecasting is an important problem with a wide range of applications. Recent works model the relations between time-series as graphs and have shown that propagating inform...
forecasts accurate forecasting structure stoic Read moreIn the evolving application of medical artificial intelligence, federated learning is notable for its ability to protect training data privacy. Federated learning facilitates collaborative model dev...
medical data mh-pflgb learning federated Read moreThe rapid development of Multimodal Large Language Models (MLLMs) is making AI-driven scientific assistants increasingly feasible, with interpreting scientific figures being a crucial task. However,...
data benchmarks captioning models computer science Read moreService liquidity across edge-to-cloud or multi-cloud will serve as the cornerstone of the next generation of cloud computing systems (Cloud 2.0). Provided that cloud-based services are predominantl...
liquidity live platform migration service cloud services robust containerized Read moreWe conducted a thorough SLR to better grasp the challenges and possible solutions associated with existing npm security tools. Our goal was to delve into documented experiences and findings. Specifi...
Read moreIn the context of goal-oriented communications, this paper addresses the achievable rate versus generalization error region of a learning task applied on compressed data. The study focuses on the di...
polynomial regression generalization error Read moreParticipatory design initiatives, especially within the realm of digital civics, are often integrated and co-developed with the very citizens and communities they intend to assist. Digital civics re...
practices embedded civics digital Read moreThe development of data-driven approaches for solving differential equations has been followed by a plethora of applications in science and engineering across a multitude of disciplines and remains ...
engineering learning machine fides fractional Read moreAttracting and retaining a steady stream of new contributors is crucial to ensuring the long-term survival of open-source software (OSS) projects. However, there are two key research gaps regarding ...
contributors oss onboarding newcomers projects Read moreIn the last twenty years, Structure from Motion (SfM) has been a constant research hotspot in the fields of photogrammetry, computer vision, robotics etc., whereas real-time performance is just a re...
on-the-fly computer sfm Read moreEquations system constructors of hierarchical circuits play a central role in device modeling, nonlinear equations solving, and circuit design automation. However, existing constructors present limi...
device constructors system circuit equations parameters Read moreBACKGROUND: It is unknown if early COVID-19 monoclonal antibody (mAb) therapy can reduce risk of Long COVID. The mAbs amubarvimab/romlusevimab were previously demonstrated to reduce risk of hospitaliz...
36 reduce week covid covid-19 outcome placebo amubarvimab/romlusevimab Read morePurpose This longitudinal study investigated distress rates in patients with advanced ovarian cancer during the COVID-19 pandemic and examined whether time, illness representations, and coping strateg...
ovarian cancer distress fear of progression coping perceptions covid advanced levels patients cancer ovarian coping Read moreIntroduction The COVID-19 pandemic period (2020 to 2022) challenged and overstretched the capacity of primary health care services to deliver health care globally. The sector faced a highly uncertain ...
healthcare access covid first nations people aboriginal people clinic use policies pandemic delivery information community health primary staff regional remote care communities Read moreBackground Since the declaration of COVID-19 as a pandemic in 2020, its main symptoms have primarily affected the respiratory system. However, it also presents other systemic manifestations, including...
covid delta & omicron variant laryngopharyngeal manifestations patients study primarily paralysis fold exhibited laryngo pharyngeal covid-19 vocal related affection Read moreAim Long-haul COVID-19 poses a profound burden to public health. According to the CDC, approximately one in five people who contract COVID-19 have lingering COVID-related symptoms 3 months after testi...
long covid disease severity veterans’ health covid-19 epidemiology covid positive veterans symptom risk acute developing covid-19 Read moreAs a novel virus, COVID introduced considerable uncertainty into the daily lives of people all over the globe since late 2019. Relying on twenty-three semi-structured interviews with parents whose c...
covid Read moreThe global pandemic due to emergence of COVID 19 has created the unrivaled public health crisis. It has huge morbidity rate never comprehended in the recent decades. Researchers have made many effor...
covid 19 potential inhibitors Read moreSince the outbreak of COVID-19 pandemic in 2020, numerous researches and studies have focused on the long-term effects of COVID infection. The Centers for Disease Control (CDC) implemented an addition...
patients covid Read moreAim Long-haul COVID-19 poses a profound burden to public health. According to the CDC, approximately one in five people who contract COVID-19 have lingering COVID-related symptoms 3 months after testi...
long covid disease severity veterans’ health covid-19 epidemiology covid positive veterans symptom risk acute developing covid-19 Read moreAim Long-haul COVID-19 poses a profound burden to public health. According to the CDC, approximately one in five people who contract COVID-19 have lingering COVID-related symptoms 3 months after testi...
long covid disease severity veterans’ health covid-19 epidemiology covid positive veterans symptom risk acute developing covid-19 Read moreMore than three years after the start of the COVID-19 pandemic, individuals are frequently reporting multiple COVID-19 infections. However, these reinfections remain poorly understood. Here, we invest...
findings electronic patients characterize following epoch million record study health initial individuals infection reinfection severe reinfections covid-19 covid Read morePurpose This longitudinal study investigated distress rates in patients with advanced ovarian cancer during the COVID-19 pandemic and examined whether time, illness representations, and coping strateg...
ovarian cancer distress fear of progression coping perceptions covid advanced levels patients cancer ovarian coping Read moreZang et al. use RECOVER EHR data to study Long COVID risk factors and apply mathematical modeling to predict the development of long COVID conditions. They find that severe acute SARS-CoV-2 infection,...
modeling pulmonary covid conditions factors predict develop associated risk acute Read moreBackground Since the declaration of COVID-19 as a pandemic in 2020, its main symptoms have primarily affected the respiratory system. However, it also presents other systemic manifestations, including...
covid delta & omicron variant laryngopharyngeal manifestations patients study primarily paralysis fold exhibited laryngo pharyngeal covid-19 vocal related affection Read moreObjective To examine the relationship between physical rehabilitation parameters including an approach to quantifying dosage with hospital outcomes for patients with critical COVID-19. Design Retrospe...
physical rehabilitation early mobilization critical illness occupational therapy physical therapy covid outcomes care < 0 am-pac covid-19 physical hospital 001 Read moreMore than three years after the start of the COVID-19 pandemic, individuals are frequently reporting multiple COVID-19 infections. However, these reinfections remain poorly understood. Here, we invest...
findings electronic patients characterize following epoch million record study health initial individuals infection reinfection severe reinfections covid-19 covid Read moreObjective To examine the relationship between physical rehabilitation parameters including an approach to quantifying dosage with hospital outcomes for patients with critical COVID-19. Design Retrospe...
physical rehabilitation early mobilization critical illness occupational therapy physical therapy covid outcomes care < 0 am-pac covid-19 physical hospital 001 Read moreBackground The emergence of COVID-19 precipitated containment policies (e.g., lockdowns, school closures, etc.). These policies disrupted healthcare, potentially eroding gains for Sustainable Developm...
newborn low- and middle-income countries inpatient care covid interrupted time series neonatal mortality policies 2021 december malawi kenya containment nigeria significant overall effects inpatient decline april interruption neonatal march covid-19 2020 tanzania mortality admissions analysis Read moreBACKGROUND: It is unknown if early COVID-19 monoclonal antibody (mAb) therapy can reduce risk of Long COVID. The mAbs amubarvimab/romlusevimab were previously demonstrated to reduce risk of hospitaliz...
36 reduce week covid covid-19 outcome placebo amubarvimab/romlusevimab Read moreBACKGROUND: It is unknown if early COVID-19 monoclonal antibody (mAb) therapy can reduce risk of Long COVID. The mAbs amubarvimab/romlusevimab were previously demonstrated to reduce risk of hospitaliz...
36 reduce week covid covid-19 outcome placebo amubarvimab/romlusevimab Read moreBackground The emergence of COVID-19 precipitated containment policies (e.g., lockdowns, school closures, etc.). These policies disrupted healthcare, potentially eroding gains for Sustainable Developm...
newborn low- and middle-income countries inpatient care covid interrupted time series neonatal mortality policies 2021 december malawi kenya containment nigeria significant overall effects inpatient decline april interruption neonatal march covid-19 2020 tanzania mortality admissions analysis Read moreZang et al. use RECOVER EHR data to study Long COVID risk factors and apply mathematical modeling to predict the development of long COVID conditions. They find that severe acute SARS-CoV-2 infection,...
modeling pulmonary covid conditions factors predict develop associated risk acute Read moreThe global pandemic due to emergence of COVID 19 has created the unrivaled public health crisis. It has huge morbidity rate never comprehended in the recent decades. Researchers have made many effor...
covid 19 potential inhibitors Read moreSince the outbreak of COVID-19 pandemic in 2020, numerous researches and studies have focused on the long-term effects of COVID infection. The Centers for Disease Control (CDC) implemented an addition...
patients covid Read moreAs a novel virus, COVID introduced considerable uncertainty into the daily lives of people all over the globe since late 2019. Relying on twenty-three semi-structured interviews with parents whose c...
covid Read moreVersion 2, November 29, 2022.; Abstract Evolutionary convergences are observed at all levels, from phenotype to DNA and protein sequences, and changes at these different levels tend to b...
changes protein expected condor convergent phenotype Read morePurpose of Review Antimicrobial resistance continues to increase throughout the world, with the impact on critically ill children in low- and middle-income paediatric intensive care units largely unkn...
multidrug-resistant organisms antimicrobial resistance colistin hiv infection prevention and control antimicrobial stewardship resistance review antimicrobial Read moreBackground The community-based antiretroviral therapy delivery (CBART) model was implemented in Benue State in Nigeria to increase access of key populations living with HIV (KPLHIV) to antiretroviral ...
key populations hiv community-based antiretroviral the... art realist evaluation programme theory improve nigeria outcomes using model study ipt safe key delivery populations kplhiv benue programme hiv kp-cbart Read moreBackground There is an urgent need to understand the interplay between SARS-CoV-2 and HIV to inform risk-mitigation approaches for HIV-infected individuals. Objectives We conclude that people living w...
hiv sars-cov-2 covid-19 co-infection art-naive effector cd8^+ art molecules hiv plwh sars-cov-2 co-infected Read moreObjectives In 2014, Ontario’s Point-of-Care (POC) test providers were advised to focus efforts on provincially defined priority populations who experience a greater risk of HIV. Our objective was to d...
hiv point-of-care testing test performance positive confirmatory characteristics positivity – poc 52 testing test hiv percent tests 7% 0 populations overall risk results compared ppv Read moreBackground Highly effective, short-course, bedaquiline-containing treatment regimens for multidrug-resistant tuberculosis (MDR-TB) and integrase strand transfer inhibitor (INSTI)-containing fixed dose...
tuberculosis mdr-tb hiv/aids bedaquiline antiretrovirals mhealth south africa adherence support include randomized using outcome outcomes trial mdr-tb hiv Read moreObjectives. To assess changes in minor consent laws for sexually transmitted infection (STI) and HIV testing, treatment, and prevention services in all 50 US states and the District of Columbia from 1...
confidentiality minor testing minors treatment sti hiv laws services prevention Read moreBACKGROUND: People living with HIV (PLWH) have a higher risk of developing hypertension compared to HIV uninfected individuals. HIV assisted partner services (aPS), where PLWH are assisted by a health...
< 0 0001 female index uptake partner assisted increase services hiv male aps relatives integrated pre p-value medication post antihypertensive screening hypertension Read moreBackground Little is known about the etiology, clinical presentation, management, and outcome of central nervous system (CNS) infections in Indonesia, a country with a high burden of infectious diseas...
cns infection indonesia adult diagnosis management outcome disease indonesia severe mortality patients infections hiv clinical presentation cns Read moreBackground In the first reported cases of human immunodeficiency virus (HIV) infection, people living with HIV (PLHIV) suffered weight loss, which was an independent predictor of mortality. Highly act...
hiv highly active antiretroviral thera... weight loss hospitalization malnutrition hiv wasting syndrome mortality mortality systematic hiv weight haart plhiv loss Read moreBackground Significant heterogeneity exists among people who use drugs (PWUD). We identify distinct profiles of syringe service program (SSP) clients to (a) evaluate differential risk factors across s...
lca harm reduction needle and syringe exchange overdose hiv hepatitis c drug use substance misuse opioids stimulants ssp factors housing lca pwud identify risk treatment individuals substance treatment/support resources classes differential syringe program class report latent using hcv history mixing sharing supplies drugs overdose Read moreBackground The sensitivity of HIV screening assays often leads to a high rate of false-positive results, requiring retests and confirmatory tests. This study aimed to analyze the capability of signal-...
hiv infection signal-to-cutoff ratio sensitivity and specificity curve infection ratios roc hiv assay ratio Read moreIntroduction Mississippi has one of the highest rates of HIV in the United States but low PrEP uptake. Understanding patterns of PrEP use can improve PrEP initiation and persistence. Methods This is a...
pre-exposure prophylaxis hiv retention barriers mississippi clinical mississippi hiv same-day care linked filled persistence Read moreIntroduction In 2022, the WHO reported that 29.8 million people around the world were living with HIV (PLHIV) and receiving antiretroviral treatment (ART), including 25 375 people in Gabon (54% of al...
hiv protease resistance mutations antiretroviral gabon arvs receiving plhiv therapeutic 5% m41l gabon mutations protease 1% 7% inhibitors hiv associated pis 6% Read moreIntravenous administration of the BCG vaccine protects non-human primates with pre-existing SIV infection from tuberculosis. Tuberculosis, caused by Mycobacterium tuberculosis (Mtb), is the most commo...
hiv immunodeficiency vaccinated siv-infected tuberculosis animals bcg intravenous Read moreBackground Input from end-users during preclinical phases can support market fit for new HIV prevention technologies. With several long-acting pre-exposure prophylaxis (PrEP) implants in development, ...
pre-exposure prophylaxis women discrete choice experiment implant sub-saharan africa hiv prevention hiv south africa preference prep women’s duration implant Read moreINTRODUCTION: Human cathelicidin LL-37 is a salivary antimicrobial peptide (AMP) with broad-spectrum activity against oral diseases, but few studies have assessed its role in children and adolescents ...
mean studies hiv calhiv ll-37 Read moreIn this cohort study, we determined time to blood pressure (BP) control and its predictors among hypertensive PLHIV enrolled in integrated hypertension-HIV care based on the World Health Organization ...
treatment enrolled hearts hiv strategy ci duo-therapy 95% ahr patients predictors bp time 0 Read moreBackground Human immunodeficiency virus (HIV) drug prophylaxis, including post-exposure prophylaxis (PEP) and pre-exposure prophylaxis (PrEP), has not yet been generally recognized and accepted by the...
healthcare workers hiv drug prophylaxis cascade cross-sectional study study analyse china = 0 prep pep prophylaxis drug knowledge cascade services hcws hiv Read moreIntroduction Globally, the incidence of HIV and syphilis can be reduced by the use of validated point of care tests (POCTs). As part of the WHO PRoSPeRo Network, we aimed to evaluate the performance, ...
hiv syphilis public health point-of-care-tests men who have sex with men clinic-based evaluation msm bioline positive reactive chembio rpr acceptability pocts syphilis dual characteristics operational hiv Read moreThe capture-recapture method is a common tool used in epidemiology to estimate the size of “hidden” populations and correct the underascertainment of cases, based on incomplete and overlapping lists o...
estimate hiv sizes model Read moreIn this cohort study, we determined time to blood pressure (BP) control and its predictors among hypertensive PLHIV enrolled in integrated hypertension-HIV care based on the World Health Organization ...
treatment enrolled hearts hiv strategy ci duo-therapy 95% ahr patients predictors bp time 0 Read morePurpose of Review To explore the intersection of chatbots and HIV prevention and care. Current applications of chatbots in HIV services, the challenges faced, recent advancements, and future research ...
hiv prevention chatbots conversational agents large language models generative ai chatbots hiv Read moreBackground and aims Liver-associated complications still frequently lead to mortality in people with HIV (PWH), even though combined antiretroviral treatment (cART) has significantly improved overall ...
pc3x pro-c5 pro-c6 hiv liver fibrosis hepatic steatosis endotrophin steatosis hiv significantly pro-c6 p = 0 fibrosis liver Read moreNitrite inhalants (poppers) are associated with HIV transmission and commonly used among young men who have sex with men (YMSM), a group at increased risk for HIV. Significant research gaps exist in u...
hiv ymsm poppers nitrite inhalants substance use chemsex ymsm hiv Read moreInternational audience; Three epidemic waves of coronavirus disease-19 (COVID-19) occurred in Madagascar from March 2020 to May 2022, with a positivity rate of severe acute respiratory s...
rvs 2020 waves viruses influenza march tested covid-19 2022 sars-cov-2 madagascar Read moreInternational audience; Annual administration and reformulation of influenza vaccines is required for protection against seasonal infections. However, the induction of strong and long-la...
cells influenza il-1β Read moreBACKGROUND: Accurate population estimates of disease incidence and burden are needed to set appropriate public health policy. The capture-recapture (C-R) method combines data from multiple sources to ...
rates estimate c-r capture-recapture hospitalization burden incidence data research influenza method Read moreBackground The elderly bear the highest burden of South Africa’s estimated annual > 10 million influenza cases and > 11,000 influenza-related deaths. Unvaccinated healthcare workers (HCWs) are at high...
influenza healthcare workers elderly vaccine vaccination south africa healthcare care health study uptake vaccine influenza south elderly participants hcws Read moreBackground: Prophylactic strategies are urgently needed for prevention of severe inflammatory responses to respiratory viral infections. Bacterial-host interactions may modify the immune response to v...
wall influenza research levels load intranasal cell reduced viral Read moreSTUDY DESIGN Cross-sectional survey. OBJECTIVES To evaluate the annual influenza vaccination coverage rate (IVCR) among community-dwelling individuals with spinal cord injury (SCI). SETTIN...
influenza switzerland vaccination injury cord ci population spinal survey sci Read morePurpose Given reduced immunity levels for seasonally occurring respiratory infections and the experience of an unusually early, severe wave of RSV infections during 2021, a preexisting clinician-led r...
acute respiratory infection rsv influenza sars-cov-2 children hospitalization fall/winter pediatric clrs 2022–2023 respiratory german patients infections admissions Read moreWithin poultry breeding sites, wild birds are often suspected to transmit pathogens, especially peridomestic species which can act as bridge hosts. In this study, we explored the role o...
birds sanitaire captive afin wild sein au described décrit influenza poultry peridomestic captives sites species avons dominantes bustards dominant breeding espèces houbara viruses virus outardes sanitary d’élevage risks risque Read moreBACKGROUND: Influenza is a global health threat to older adults, and the influenza vaccine is the most effective approach to prevent influenza infection. However, influenza vaccination coverage among ...
kap conducted medical study educational video-led students vaccine vaccination influenza adults Read moreBackground/Aims To quantify the risk of death among people with vasculitis during the UK 2020 COVID-19 epidemic compared with baseline risk, risk during annual influenza seasons and risk of death in ...
grants/research person-years research vifor pharma support age received epidemic annual funding asmr 2020 covid-19 mortality influenza march-april population risk people vasculitis none Read moreBackground Respiratory viral illnesses among children are a prominent cause of morbidity and mortality in the developing world. The aim of this study is to understand the seasonal pattern and surge of...
influenza rsv island respiratory virus ili nicobarese island nicobar car virus viral infections viruses Read moreBackground The cytokines play an essential role in acute inflammatory processes, and the IL-17 may be responsible for ambiguous aspects, and the correlation with genetic polymorphisms could improve th...
influenza a virus h1n1 subtype influenza immunohistochemistry polymorphism influenza il-17a Read moreOBJECTIVE: To study the efficacy and safety of arbidol hydrochloride tablets as a treatment for influenza-like diseases. METHODS: In this multicenter, randomized, controlled, open label study, a total...
treated patients remission incidence adverse influenza time influenza-like tablets significant difference Read moreBackground Previous studies provided some evidence of meteorological factors influence seasonal influenza transmission patterns varying across regions and latitudes. However, research on seasonal infl...
seasonal influenza köppen geiger climate zones classi... chinese mainland seasonality decomposition local indicators of spatial associ... summer patterns moran’s average season influenza seasonal cfa cwa system ir zones spatial climate < 0 001 Read moreBACKGROUND: The potential benefits of using rapid influenza diagnostic tests (RIDTs) in urgent care facilities for clinical care and prescribing practices are understudied. We compared antiviral and a...
antibiotic urgent participants using influenza diagnostic ci 95% analysis care compared patients prescribing ridt odds Read moreForecasting influenza in a timely manner aids health organizations and policymakers in adequate preparation and decision making. However, effective influenza forecasting still remains a challenge de...
influenza model pandemic historical forecasting Read moreAim The aim of this study was to complete a descriptive qualitative investigation of parents’ perceptions of the barriers and facilitators to flu vaccination for pre-school children. Subject and metho...
influenza vaccine pre-school children vaccine hesitancy parental qualitative participants vaccinated vaccination flu children Read moreForecasting influenza in a timely manner aids health organizations and policymakers in adequate preparation and decision making. However, effective influenza forecasting still remains a challenge de...
influenza model pandemic historical forecasting Read moreBACKGROUND AND AIMS: Patients with glomerulonephritis may have an increased risk of influenza infection and morbidity, but vaccine coverage remained low with little data on acceptance in glomeruloneph...
survey glomerulonephritis acceptance healthcare patients influenza vaccine awareness Read moreForecasting the hospitalizations caused by the Influenza virus is vital for public health planning so that hospitals can be better prepared for an influx of patients. Many forecasting methods have b...
learning machine mean predictors individual random influenza forecasting Read moreOBJECTIVES: To examine inpatient vaccine delivery across a national sample of children’s hospitals. METHODS: We conducted a retrospective cohort study examining vaccine administration at 49 children’s...
children’s vaccines hepatitis influenza children administered hospitalizations hospitals Read moreInternational audience; Studies comparing outcomes of ICU patients admitted for either COVID-19 or seasonal influenza are limited. Our objective was to describe baseline clinical profile...
paris outcomes status failure hospitals mechanical invasive survival icu covid-19 ventilation patients influenza chronic Read moreBACKGROUND: Immunosuppressive therapy (IS) has altered the course of Inflammatory Bowel Disease (IBD). IBD patients are at considerable risk of developing vaccine-preventable illness and are even more...
pneumonia immunosuppressive therapy ibd covid-19 appropriate influenza patients vaccinations received pneumococcal shingles intervention hepatitis vaccine Read moreOBJECTIVE: Influenza virus, which is associated with high level of morbidity and mortality, has been recently considered a public health concern; however, the methods of choice to control and treat it...
assay inhibition rna pomegranate extract peel virus replication ppe study influenza viral Read moreBACKGROUND: In recent years, accumulating evidences have revealed that influenza A virus (IAV) infections induce significant differential expression of host long noncoding RNAs (lncRNAs), some of whic...
differentially h1n1 a549 influenza host virus iav lncrnas Read moreBackground To achieve climate neutrality, fundamentally new concepts of circularity need to be implemented by the building sector as it contributes to 40% of anthropogenic CO_2 emission. Fungal biotec...
fungal-based composite material circular economy bioeconomy hemp composite material mycelium-based material compressive strength flexural strength tensile strength flammability insulation insulation strength fossil particleboards replace water composite composites fomentarius Read moreMycelium-bound composites are potential alternatives to conventional materials for a variety of applications, including thermal and acoustic building panels and product packaging. If the reactions of ...
mycelium network fungal materials environmental sensors oscillations biosensor electrical mycelium-bound Read moreBackground The impact of probiotic strains on host health is widely known. The available studies on the interaction between bacteria and the host are focused on the changes induced by bacteria in the ...
probiotic redox activity membrane potential viability enzymatic activity viability membrane tnf-α host potential < 0 strains cells probiotic medium culture eukaryotic • presence environment significantly 001 bacteria ssp changes adolescentis cell 01 Read moreBackground Infection with Helicobacter pylori as the cause of gastric cancer is a global public health concern. In addition to protecting germs from antibiotics, biofilms reduce the efficacy of H. pyl...
whole-genome sequences snp variants biofilm formation antibiotic resistance infectious disease formation helicobacter pylori snps biofilm Read moreBackground Enterocytozoon bieneusi, Encephalitozoon spp., Cryptosporidium spp., and Giardia duodenalis (G. intestinalis) are enteric pathogens that cause diarrhea in pigs. This study aimed to determin...
spp. internal transcribed spacer (its) spp. diarrheic pigs coinfection prevalence chongqing parasites sichuan detected pigs duodenalis bieneusi hellem diarrheic cuniculi encephalitozoon Read moreResistance mechanisms are a shelter for Acinetobacter baumannii to adapt to our environment which causes difficulty for the infections to be treated and WHO declares this organism on the top of pathog...
efflux pump adejkl efflux pump inhibitors cinnamomum oil efflux pump clinical imipenem strains resistance baumannii Read moreBackground Allergic rhinitis (AR) is characterized by airway inflammation in nasal mucosa from inhaled allergens and interleukin (IL)-33 is the potent inducer of Th2 inflammation in allergic nasal epi...
allergic rhinitis interleukin-33 necroptosis nasal epithelium arne cellular nasal il-33 epithelium inflammation necroptosis cells th2 ar epidermidis production allergic Read moreBackground The ascomycetous heterothallic yeast Wickerhamomyces anomalus (WA) has received considerable attention and has been widely reported in the winemaking industry for its distinctive physiologi...
ethanol stress trehalose transcriptomics antioxidant es ethanol stress trehalose Read moreSince the emergence of SARS-CoV-2 in December 2019, more than 12,000 mutations in the virus have been identified. These could cause changes in viral characteristics and directly impact global public h...
sanger sars-cov-2 monitoring variants sequencing recombinants samples sanger Read moreBackground Candidatus Ornithobacterium hominis ( O. hominis ), which was identified in nasopharyngeal swabs from Egypt, has been associated with respiratory disorders in humans. O. hominis , a recentl...
nasopharyngeal microbiome antimicrobial resistance genes gliding virulence using identified encoding hominis genes resistance genome Read moreBackground The gut microbiota plays a crucial role in regulating the host’s immune responses during aging, which was characterized by a different abundance of bacteria in several age groups. Main body...
gut microbiota aging inflammatory disease metabolism probiotic gut microbiota Read morePlant growth promoting microbe assisted phytoremediation is considered a more effective approach to rehabilitation than the single use of plants, but underlying mechanism is still unclear. In this stu...
phytoremediation plant growth promoting microbe plant–microbe association cd contaminant mechanism plant increased microbe strain promoting phytoremediation growth assisted Read moreBackground Co-infection with other pathogens in coronavirus disease 2019 (COVID-19) patients exacerbates disease severity and impacts patient prognosis. Clarifying the exact pathogens co-infected with...
covid-19 co-infection upper respiratory tract microbiota tract negative samples candida albicans upper covid-19 patients positive Read moreBackground The microbiota in fish external mucus is mainly known for having a role in homeostasis and protection against pathogens, but recent evidence suggests it is also involved in the host-specifi...
teleost fish parasitism abiotic factor immunity metabarcoding seasonal fluctuation study bacterial diversity ectoparasites monogenean external lamellodiscus microbiota fish Read moreIn this study fungal strains were investigated, which had been isolated from eggs of the cereal cyst nematode Heterodera filipjevi , and roots of Microthlaspi perfoliatum ( Brassicaceae ). The morphol...
endophytes nematophagous fungi new species phylogeny plant parasitic nematodes taxonomy phylogenetic fungus nematodes hyphae strains nematode Read moreBackground Brucellosis is an economically devastating animal disease and has public health concern. Serological methods such as Rose Bengal Plate Test (RBPT), Complement Fixation Test (CFT), and Indir...
brucella species diagnosis cft i-elisa rbpt pcr brucellosis sensitivity test using serological brucella specificity 100% 95% detected abortus comparative cattle sheep cft goats Read moreChrysomyxa rusts cause significant damage to spruce in both natural forests and plantations. Particularly, Three Chrysomyxa species, Chrysomyxa deformans , Chrysomyxa qilianensis , and Chrysomyxa rhod...
dna-based diagnostics lamp spruce needle rust bud rust china lamp assay detection rust spruce Read moreBackground Circadian rhythms, observed across all domains of life, enable organisms to anticipate and prepare for diel changes in environmental conditions. In bacteria, a circadian clock mechanism has...
circadian rhythm circadian clock diurnal cycle diel cycle oscillations symbiosis gut microbiota microbiota diel gut bacteria rhythms mechanisms host circadian Read moreVarious eco-friendly techniques are being researched for synthesizing ZnO-NPs, known for their bioactivity. This study aimed at biosynthesizing ZnO-NPs using Streptomyces baarnensis MH-133, characteri...
zno-nps biosynthesis nanoemulsion characterization antibacterial activity cytotoxicity treatments activity mh-133 analysis cytotoxicity concentration bacteria /ml compound nanoemulsion combinations zno-nps ka 0 fici mic streptomyces baarnensis ka-zno-nps mrsa pneumonia combination form Read morePurpose Microbial resources are abundant in fermented grains of the Chinese Fen-flavor Baijiu , which is closely related to the quality of Baijiu . The purpose of this study was to investigate the mic...
metagenomics amplicon sequencing microbial community spearman correlation stage species fermentation microbial dominant baijiu Read moreBackground COVID-19 emerged in late 2019 and has occasioned more than 765 millions cumulative cases and 6.9 millions of deaths globally. Notably, around 70% of patients with severe COVID-19 are men. T...
covid-19 microbiome cytokines inflammation women-s health prevotella = 1 status load = 0 covid-19 ace2 microbiome expression health Read moreBackground Infection with Helicobacter pylori as the cause of gastric cancer is a global public health concern. In addition to protecting germs from antibiotics, biofilms reduce the efficacy of H. pyl...
whole-genome sequences snp variants biofilm formation antibiotic resistance infectious disease formation helicobacter pylori snps biofilm Read moreBackground Drought stress is currently the primary abiotic stress factor for crop loss worldwide. Although drought stress reduces the crop yield significantly, species and genotypes differ in their st...
am fungi dual inoculation conditions effect yield plants condition drought stress Read moreBackground Uterine infections, primarily caused by bacterial pathogens, pose a significant problem for dairy farmers worldwide, leading to poor reproductive performance and economic losses. However, t...
antimicrobial resistance bacterial isolation dairy cows uterine infection samples antimicrobials susceptibility cumulative uterine spp dairy resistance postpartum infections 5% antimicrobial cows bacteria Read moreBackground Hyaluronic acid (HA) has gained significant attention due to its unique physical, chemical, and biological properties, making it widely used in various industries. This study aimed to scree...
cytotoxicity fermentation parameters hyaluronic acid (ha) cancer pneumoniae effect h15 inhibitory isolates cell lines ha bacterial Read morePrognosticating the clinical outcome of neurological diseases is essential to guide treatment and facilitate decision-making. It usually depends on clinical and radiological findings. Biomarkers have ...
protein s100b Read moreThis case describes a 30-year-old Hispanic male who presented with a significant headache that started after a period of weightlifting and squatting. The patient was diagnosed with a basilar artery di...
dissection Read moreBACKGROUND AND PURPOSE: Both dual-energy CT and quantitative susceptibility mapping can evaluate iron depositions in the brain. The purpose of this study was to compare these 2 techniques in evaluatin...
nigra substantia healthy depositions p < 05 nucleus brain susceptibility ct bilateral dual-energy iron quantitative mapping values magnetic globus pallidus Read moreINTRODUCTION: Functional neurological disorder (FND) is a common cause of referral to neurology services. FND has been shown to lead to significant healthcare resource use and is associated with signi...
indirect resource patients fnd Read moreBACKGROUND AND AIMS: Guillain-Barré syndrome (GBS) is usually triggered by an infection. Vaccination is mentioned as a possible trigger in a small number of GBS cases. The aim of this study was to not...
precipitating pandemic significantly characteristics syndrome patients gbs clinical vaccination covid-19 infection Read moreBACKGROUND: Myelin oligodendrocyte glycoprotein-associated disorders (MOGAD) is an autoimmune central nervous system disease. Antigen-specific immune tolerance using nanoparticles such as Polylactic-c...
conjugated using affiliation score autoimmune tolerance immune administration eae Read moreBACKGROUND: Idiopathic intracranial hypertension (IIH) is a neurometabolic condition severely impacting the quality of life of people living with IIH (PwIIH). Most PwIIH are overweight or live with ob...
perspective research hcps weight iih management Read moreParental input is considered a key predictor of language achievement during the first years of life, yet relatively few studies have assessed the effects of parental language input and parent–infant i...
parental long-term brain effects interactions input effect ct uniquely ability af slf language development myelination matter white Read moreBACKGROUND AND PURPOSE: Surgical clipping and endovascular treatment are commonly used in patients with unruptured intracranial aneurysms. We compared the safety and efficacy of the 2 treatments in a ...
surgical failure surgery risk primary outcome relative 95% ci treatment patients clipping aneurysms intracranial unruptured endovascular Read moreINTRODUCTION: It is widely demonstrated that high frequency (HF) repetitive transcranial magnetic stimulation (rTMS) has facilitative effects and is therefore capable to inducing changes in motor resp...
players study mep hf stimulation volleyball coordination Read moreBACKGROUND: The UK Medicines Health products Regulation Agency instructs that valproate prescriptions should be restricted in women of childbearing age to those consenting to the Pregnancy Prevention ...
meet care ppp valproate Read moreINTRODUCTION: It is widely demonstrated that high frequency (HF) repetitive transcranial magnetic stimulation (rTMS) has facilitative effects and is therefore capable to inducing changes in motor resp...
players study mep hf stimulation volleyball coordination Read moreBACKGROUND: Middle meningeal artery embolization is an emerging treatment option for chronic subdural hematomas. PURPOSE: Our aim was to assess outcomes following middle meningeal artery embolization ...
radiologic rates reoperation primary chronic data complications clinical patients treatment hematoma outcomes recurrence subdural embolization Read moreOBJECTIVE: This study was to investigate the therapeutic effect of high-frequency repetitive magnetic stimulation (HF-rMS) at the sacrum for chronic constipation in Parkinson’s patients (PD). MATERIAL...
magnetic stimulation parkinson’s significant patients scale sacrum pd hf-rms chronic constipation scores Read moreBACKGROUND: The habenula is a major regulator of serotonergic neurons in the dorsal raphe, and thus of brain state. The functional connectivity between these regions is incompletely characterized. Her...
vhb displayed simple excitatory modeling response dorsal habenula neurons raphe Read moreAcute cerebellar ataxia (ACA) is a self-limited syndrome that is frequently post-infectious, most commonly following Varicella infection having an autoimmune mechanism. ACA is the commonest cause of c...
infection aca acute ataxia Read moreBACKGROUND: Nationally representative studies evaluating the impact of the COVID-19 pandemic on haemorrhagic stroke outcomes are lacking. METHODS: In this pooled cross-sectional analysis, we identifie...
00 month p<0 0 patients outcomes ich Read moreThe macaque middle temporal (MT) area is well known for its visual motion selectivity and relevance to motion perception, but the possibility of it also reflecting higher-level cognitive functions has...
analyses manipulation signals multiple responses temporal motion mt distinct strategy Read moreDespite the indispensable role that astrocytes play in the neurovascular unit, few studies have investigated the functional impact of astrocyte signaling in cognitive decline and dementia related to v...
vessel cerebral dementia cognitive targeting cerebrovascular mice ca 2+ hhcy diet astrocytes signaling astrocyte Read moreBACKGROUND: Both Impulse-control disorders and related behaviours (ICD-RB) and restless leg syndrome (RLS) are relatively common in patients with Parkinson’s disease, but little is known are they rela...
18 study pd disorders icd icd-rbs patients compulsive Read moreIn this narrative review, we examine biological processes linking psychological stress and cognition, with a focus on how psychological stress can activate multiple neurobiological mechanisms that dri...
review neurocognitive cognitive Read moreBackground There are increasing reports of cases of Guillain-Barré syndrome (GBS), as an adverse event of an immune checkpoint inhibitor (ICI) but postmarket data on the incidence of this remains scar...
data event reports reporting study avelumab faers checkpoint associated adverse ror Read moreThe Slack channel (KCNT1, Slo2.2) is a sodium-activated and chloride-activated potassium channel that regulates heart rate and maintains the normal excitability of the nervous system. Despite intense ...
charged site residues e373 slack chloride interaction sites channel sodium Read moreOBJECTIVE: The goal of this study was to determine the base rates of failing proposed embedded validity indicators (EVIs) for the National Institutes of Health Toolbox Cognition Battery (NIHTB-CB) in ...
crystallized data false-positive failure tests scores age-adjusted validity standard using evi failures multivariable nihtb-cb cognition rates sd Read moreBACKGROUND AND PURPOSE: The detection rate of premortem MR imaging endolymphatic hydrops is lower than that of postmortem endolymphatic hydrops in Ménière disease, indicating that current MR imaging t...
ménière disease p < detection imaging sequences 3d-zoomit 3d endolymphatic real tse reconstruction ir inversion-recovery hydrops ratio Read moreParkinson's disease (PD) is a neurodegenerative disease that includes motor impairments, such as tremor, bradykinesia, and postural instability. Although eye movement deficits are commonly found in sa...
demonstrate hand tasks task parkinson patients controls eye movement pd targets oculomotor movements disease Read moreBACKGROUND: Positron emission tomography (PET) imaging in early Parkinson's disease (PD) subjects reveals that increased dopamine (DA) turnover and reduced dopamine transporter (DAT) density precede d...
density control parkinson pd compared striatum decreased rats ipsilateral dopaminergic model pff da imaging Read moreInternational audience; α-synucleinopathies, encompassing Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy, are devastating neurodegenerative diseases for whic...
lewy disease dementia α-synuclein atrophy bodies multiple parkinson infectious agents system potential Read moreDeep Brain Stimulation (DBS) is a successful and encouraging way of treating abnormal movement diseases, such as Parkinson’s Disease (PD). The success of the surgical procedure depends ...
decision procedure sciences proposons deep disease apprentissage learning brain parkinson stimulation mesh Read moreBACKGROUND: Continuous, subcutaneous (SC) levodopa/carbidopa infusion with ND0612 is under development as a treatment for patients with Parkinson's disease (PD) and motor fluctuations. OBJECTIVE: Eval...
levodopa/carbidopa study discontinuation safety nd0612 subcutaneous parkinson Read moreInternational audience; Objective: Survival of patients with monogenic Parkinson's disease may depend on the causative genes associated with the disease. In this study, we compare surviv...
monogenic forms p = 0 disease lrrk2 mutations survival patients parkinson Read moreInternational audience; Parkinson's disease is a neurodegenerative disease that affects more than 6.1 million people worldwide. In the clinical routine, the main tool to diagnose and mon...
eye descriptor based gait parkinson disease motion Read moreOne of the most catastrophic neurological disorders worldwide is Parkinson's Disease. Along with it, the treatment is complicated and abundantly expensive. The only effective action to control the p...
patients whom study disease parkinson machine learning Read moreInternational audience; Background: Parkinson's disease (PD) is characterized by a severe loss of the dopaminergic (DA) neurons in the substantia nigra pars compacta (SNpc). Perturbation...
parkinson glutaredoxin downregulation dopaminergic da pd grx1 snpc Read moreBACKGROUND: Dystonia is an understudied motor feature of Parkinson's disease (PD). Although considerable efforts have focused on brain oscillations related to the cardinal symptoms of PD, whether dyst...
parkinson spectral hand beta stn power foot rest pd Read morePURPOSE: To report convergence insufficiency in a patient with Parkinson's’ disease stimulated by turning on the deep brain stimulator. OBSERVATIONS: 72-year-old male with Parkinson's disease and hype...
evaluation brain deep stimulation disease near parkinson stimulator insufficiency convergence Read moreFlexible Endoscopic Evaluation of Swallowing (FEES) is one of two diagnostic gold standards for pharyngeal dysphagia in Parkinson's disease (PD), however, validated global outcome measures at the pati...
digest oropharyngeal dysphagia parkinson aspiration pneumonia malnutrition validity dysphagia pharyngeal swallowing overall outcome digest-fees = 0 pd < 0 001 Read moreBackground Traditionally, functional neurosurgery relied in stereotactic atlases and intraoperative micro-registration in awake patients for electrode placement in Parkinson’s disease. Cumulative expe...
dbs parkinson subthalamic nucleus asleep oarm Read moreLimited accessibility to neurological care leads to underdiagnosed Parkinson's Disease (PD), preventing early intervention. Existing AI-based PD detection methods primarily focus on unimodal analysi...
disease analysis science ufnet accuracy pd computer Read moreBackground and objectives: Dynamic handwriting analysis, due to its non-invasive and readily accessible nature, has recently emerged as a vital adjunctive method for the early diagnosis of Parkinson...
dynamic architecture analysis diagnosis handwriting $0 parkinson disease network Read moreIntraneuronal accumulation of aggregated α-synuclein is a pathological hallmark of Parkinson’s disease. Therefore, mechanisms capable of promoting α-synuclein deposition bear important pathogenetic im...
fibrils l444p significantly extracts disease control parkinson’s gba parkinson α-synuclein fibroblasts Read moreINTRODUCTION: Given the rapidly aging population in both the United States and Mexico, rates of Parkinson's disease (PD) are likely to rise in both countries, suggesting that the number of individuals...
parkinson mexico united pd Read moreBursts of beta frequency band activity in the basal ganglia of patients with Parkinson's disease (PD) are associated with impaired motor performance. Here we test in human adults whether small variati...
parkinson patients activity disease recent networks velocity locally stn ganglia basal cumulative motor performance Read moreBackground Clinical trials have provided evidence that transplants of dopaminergic precursors, which may be replaced by new in vitro stem cell sources, can integrate into the host tissue, and alleviat...
angiotensin at1 autoimmunity cell grafts cell transplantation microglia neurodegeneration parkinson rejection renin-angiotensin system rejection patients grafting at1 antibodies non-hla receptor dopaminergic effects rats candesartan grafted neurons at1-aa graft Read moreInternational audience; Parkinson's disease (PD) and the parkinsonian variant of Multiple System Atrophy (MSA-P) are two neurodegenerative diseases which share similar clinical features,...
parkinson multiple atrophy system voiced disease differential diagnosis Read moreIn this paper, we evaluate the contribution of different handwriting modalities to the diagnosis of Parkinson's disease. We analyse on-surface movement, in-air movement and pressure exerted on the t...
disease parkinson in-air pd features diagnosis movement handwriting Read moreWCNR, 11th World Congress for Neurorehabilitation, Lyon, FRANCE, 07-/10/2020 - 11/10/2020; 1.Question: Patients with Parkinson disease (PD) report difficulties walking while performing a...
study disease cadence score dlpfc dorsolateral prefrontal patients hbo2 controls parkinson dt pd activity ± conditions st Read moreBACKGROUND: Parkinson's disease (PD) is a neurodegenerative disorder with a significant immune component, as demonstrated by changes in immune biomarkers in patients' biofluids. However, which specifi...
changes patients parkinson cd163 biomarkers correlated alpha‐synuclein pd Read moreParkinson's disease (PD) is a neurodegenerative disorder anatomically characterized by a progressive loss of dopaminergic neurons in the substantia nigra compacta (SNpc). Much less known, yet clinical...
prebötc decreased parkinson disease pd neurons model Read moreBACKGROUND: The most common genetic risk factor for Parkinson's disease known is a damaging variant in the GBA1 gene. The entire GBA1 gene has rarely been studied in a large cohort from a single popul...
d140h + p compared e326k gene controls 0 parkinson gba1 patients Read moreWe analyze $\textit{JWST}$ CEERS NIRCam images to present {the first estimate} of the observed fraction and properties of bars out to $z \sim 4$. We analyze a sample of 1770 galaxies with stellar ma...
5$ images bars $z bar results barred galaxies Read moreMillisecond pulsars are subject to accelerations in globular clusters (GCs) that manifest themselves in both the first and second spin period time derivatives, and can be used to explore the mass di...
millisecond 6752 pulsars Read moreThe SDSS-IV/MaNGA Survey data provide an unprecedented opportunity to study the internal motions of galaxies and, in particular, represent the largest sample of barred galaxy kinematic maps obtained...
modeling nirvana Read moreBinary neutron star (BNS) mergers can be sources of ultrahigh-energy (UHE) cosmic rays and potential emitters of UHE neutrinos. The upcoming and current radio neutrino detectors like the Giant Radio...
neutrinos detectors uhe radio Read moreWe report on high-sensitivity neutral hydrogen observations toward the gas-rich interacting galaxies NGC 3395/3396 with the Five-hundred-meter Aperture Spherical radio Telescope (FAST). Compared to ...
interacting plume tail galaxies hi observations Read moreSelf-Interacting Dark Matter models can successfully explain dark matter (DM) production through interactions confined within the dark sector. However, they often lack measurable experimental signal...
dark scalar Read moreA new model for dark matter is put forward which consists of uniform droplets of Bose Einstein condensate. In this model, structure forms rapidly, shortly after the hot big bang plasma de-ionises. T...
matter model Read morePrecise and accurate mass and radius measurements of evolved stars are crucial to calibrating stellar models. Stars in detached eclipsing binaries (EBs) are excellent potential calibrators because t...
asas-sn measurements eclipsing ebs systems mass astrophysics stars binaries radius stellar Read moreWe use the high-resolution HR-DEMNUni simulations to compute cross-correlations of the Cosmic Neutrino Background C$_{\nu}$B with other observables, namely: cold dark matter density, effective weak ...
neutrino Read moreWe combined a principal component analysis (PCA) and spectroscopy to investigate the origin of the soft excess in narrow-line Seyfert 1 galaxy Ark 564 with XMM-Newton observations over a period of t...
reflection analysis components principal Read moreWe summarize our exploratory investigation into whether Machine Learning (ML) techniques applied to publicly available professional text can substantially augment strategic planning for astronomy. W...
using astronomy results corpus models Read moreWhite dwarf atmospheres are frequently polluted by material from their own planetary systems. Absorption features from Ca, Mg, Fe and other elements can provide unique insights into the provenance o...
accretion material elements noise consider distribution white astrophysics Read moreWe investigate the impact of using multipoint p-T profiles of varying complexity on the retrieval of synthetically generated hot Jupiter transmission spectra modelled after state-of-the-art observat...
using jwst underlying isothermal parameters prescription profile atmospheric retrievals astrophysics Read moreGravitational lensing offers a powerful tool for exploring the matter distribution in the Universe. Thanks to their low frequencies and phase coherence, gravitational waves (GWs) allow for the obser...
\sim lensing lensed lisa $m_{\rm gws wofs gravitational Read moreIn the host galaxies of radio AGN, kinematically disturbed gas due to jet-driven feedback is a widely observed phenomenon. Simulations predict that the impact of jets on the surrounding gas changes ...
determine kinematics [oiii] sources impact agn spectrum gas radio Read moreThe cores of pulsars are expected to become superconducting soon after birth. The transition to type-II superconductivity is associated with the bunching of magnetic field lines into discrete superc...
field tubes core transition crust magnetic superconducting flux waves hall Read moreWithin the RoadMap project we investigated the microphysical aspects of particle collisions during saltation on the Martian surface in laboratory experiments. Following the size distribution of ejec...
charges astrophysics Read moreThis study presents a systematic approach to optimize the scheduling of exoplanet observations using the James Webb Space Telescope (JWST), focusing on targets discovered by the Transiting Exoplanet...
exoplanet approach transit jwst astrophysics Read moreA key scientific goal of exoplanet surveys is to characterize the underlying population of planets in the local galaxy. In particular, the properties of accreting protoplanets can inform the rates a...
compute method models surveys h-alpha accreting formation astrophysics rates Read moreThe Dark Energy Spectroscopic Instrument (DESI) Peculiar Velocity Survey aims to measure the peculiar velocities of early and late type galaxies within the DESI footprint using both the Fundamental ...
velocities spectroscopic dispersion survey galaxies peculiar velocity desi astrophysics Read moreWith recent missions such as advanced space-based observatories like the Solar Dynamics Observatory (SDO) and Parker Solar Probe, and ground-based telescopes like the Daniel K. Inouye Solar Telescop...
computer vision data opportunities challenges physics solar deep spbd Read morePrimordial gravitational waves from the very early stages of the universe, such as inflation or bounce processes, are an irreducible cosmological source of the stochastic gravitational wave backgrou...
evolution astrophysics generic waves primordial cosmology bounce Read moreWe perform $3+1$ relativistic numerical simulations to study primordial black hole (PBH) formation from the collapse of adiabatic super-horizon non-spherical perturbations generated from curvature f...
hole $p$ ellipticity critical threshold black non-spherical Read moreGrowing observational evidence suggests that enhanced mass loss from the progenitors of core-collapse supernovae (SNe) is common during $\sim1$ yr preceding the explosion, creating an optically thic...
csm loss sn breakout mass sne Read moreThe galaxy cluster Abell 496 has been extensively studied in the past for the clear sloshing motion of the hot gas on large scales, but the interplay between the central radio galaxy and the surroun...
abell kpc 496 episode galaxy cluster 0 astrophysics radio Read moreBackground A new population of older people is growing: the oldest-old. The care of the oldest-old (individuals aged 90 and over) is a new challenge in primary care. This study aimed to analyze the pe...
age 80 and over aging general practice independent living longevity qualitative research gps study disengagement shift practitioners individual care Read moreStudying human values is instrumental for cross-cultural research, enabling a better understanding of preferences and behaviour of society at large and communities therein. To study the dynamics of ...
subreddits study Read moreBACKGROUND: Kawasaki disease (kDa) is a multisystemic vasculitis affecting medium and small vessels with a predilection for the coronary arteries. It appears to be very similar to the pediatric multis...
whereas coronary entities study kda vs pims patients Read moreBackground Uroliths are stones formed in the urinary tract. Analysis of stones helps to identify risk factors for their development and prevention of recurrence. Standard stone analysis using modern t...
uroliths analysis composition common nigeria 155 analysis oxalate study uroliths stones tract calcium urinary Read moreBACKGROUND: Under the restriction of social activities during the coronavirus disease 2019 (COVID-19) pandemic, there was concern about the loss of muscle mass due to a decrease in physical activity f...
osteoporosis covid-19 mm living postmenopausal pandemic loss ml study Read moreBACKGROUND: Acarbose slows down the intestinal absorption of carbohydrates, but its effects on the secretion of incretins are still poorly known. This study aimed to examine the effects of single-dose...
study glucose newly secretion registration auc underwent receiving single-dose levels mmt ogtt mixed meal patients diagnosed acarbose p < 0 glucagon 05 Read moreBackground This study aimed to compare patient experiences during bronchoscopy procedures using either topical anesthesia (TA) or monitored anesthesia care (MA). The goal was to identify circumstances...
anesthesia bronchoscopy complication satisfaction visual analogue scale levels study anesthesia time included tolerance procedure procedures Read moreINTRODUCTION: Pre-eclampsia (PE) affects about 5% of Chinese pregnant women and is a major cause of maternal and perinatal morbidity and mortality. The first trimester screening model developed by the...
pregnant ethics daily study pe women screening trial metformin risk preterm-pe Read moreBackground COVID-19 increases the risk of acute ischemic stroke. The objective of this study is to identify the risk factors, comorbidities, and outcomes in COVID-19 patients with acute ischemic strok...
covid-19 ischemic stroke stroke stroke study clinical ischemic patients Read moreINTRODUCTION: Uncontrolled blood pressure is one of the main risk factors for cardiovascular disease and death in Low-income and middle-income countries. Improvements to medication adherence and lifes...
hypertensive 3 months text4bp measures trial patients acceptability messaging ethics text nepal study Read morePurpose: Suicidal ideation and attempts in youth are a growing health concern, and more data are needed regarding their biological underpinnings. Asthma is a common chronic inflammatory disorder in yo...
study data controlling suicidality 0 sa association asthma factors Read moreBACKGROUND: Delirium is an underdiagnosed condition and this may be related, among other causes, to the incorrect use of assessment tools due to lack of knowledge about cognitive assessment and lack o...
training unit study intensive assessment delirium care cam-icu lack Read moreThe motor impairments of cerebral palsy (CP) are typically accompanied by subsequent musculoskeletal issues, seizures, and abnormalities of sensation, intelligence, communication, and behaviour. These...
category caries dental kids poor health study participants control cp Read moreHigh temperature geothermal projects for electricity production are in France mostly localized in the basement of basins linked to the West European Rifting event. The basement of these...
basins interface fossés zone study basement failles fault Read moreBackground The incidence of Total Shoulder Arthroplasty (TSA) and Reverse Total Shoulder Arthroplasty (RTSA) is constantly increasing. As a result, the interest in post-surgical rehabilitation has gro...
shoulder prosthesis physical therapy modalities total shoulder replacement shoulder joints physical therapy specialty arthroplasty abduction stated total study tsa survey participants italian strengthening shoulder rotation practice clinical rtsa rehabilitation Read moreInternational audience; The direction of the association between mental health and adiposity is poorly understood. Our objective was to empirically examine this link in a UK study. This ...
uk women risk study adiposity baseline disorder mental common Read moreOBJECTIVE: Left ventricular (LV) systolic synchrony is defined as simultaneous activation of corresponding cardiac segments. Impaired synchrony has some adverse cardiovascular effects, such as LV dysf...
associated study ts-sd-6 ts-6 relationship fat systolic eft Read moreBackground: Insomnia is associated with several adverse health outcomes. Small clinical studies have suggested that an inferior nutrition status is a potential explanation, but to our knowledge, this ...
fat vegetables health study trans p-trend difficulty sodium associated 0 sleep lower probable Read moreBACKGROUND: The Shock Index Creatinine (SIC) scoring is a recently developed tool for risk stratification patients. These updated scoring was already used in ST-Elevation Myocardial Infarction (STEMI)...
analysis predictive patients study sic score acs Read moreOBJECTIVES: This study aimed to assess the coverage and explore enablers and challenges in implementation of direct benefit transfer (DBT) cash incentive scheme for patients with tuberculosis (TB). DE...
time received transfer instalment treatment implementation receipt sector private tb dbt coverage study patients Read moreBACKGROUND: The clinical endoscopic phenotypes of gastroesophageal reflux disease (GERD) are classified as Barrett's esophagus (BE), erosive esophagitis (EE) and non-erosive gastroesophageal reflux di...
reflux phenotypes gastroesophageal tnf-α gerd control endoscopic genes esophageal biopsies expression study 05 il-1b p < 0 patients increased exhibited Read moreBackground Smoking is a significant public health problem, and there is a scarcity of documents regarding its severity, particularly in developing countries. This study aimed to determine factors rela...
smoking smoking intensity cigarette adults tlgs tehran daily factors 95%ci 0 vs smokers unemployed adult study Read moreBackground Over the past years, Mozambique has implemented several initiatives to ensure equitable coverage to health care services. While there have been some achievements in health care coverage at ...
health care coverage health inequality national surveys socioeconomic inequalities mozambique children net study variables period fansidar prophylaxis treatment inequalities significant observed reductions fever survey insecticide-treated mozambique coverage care health inequality Read moreDeveloping a system to detect online offensive language is very important to the health and the security of online users. Studies have shown that cyberhate, online harassment and other misuses of te...
multiple performance computer bert online model datasets effects study transfer Read moreBackground Liver is a complex, highly vascular organ, where anatomical variations are the norm. This study aimed to analyze all the three hepatic vascular anatomical variations in a single study which...
hepatic artery portal vein hepatic vein anatomical variations anatomical anomalies anomalies contrast-enhanced single variant study common rhv artery variations Read moreObjectives To study the relationship between the ablation range and applied energy of laser ablation (LA) and microwave ablation (MWA) in papillary thyroid microcarcinoma (PTMC). Methods A total of 20...
papillary thyroid microcarcinoma ultrasonography microwaves laser therapy ablation techniques ht laser microwave diameter • ablation 0 r_av/e ptmc papillary thyroid microcarcinoma mwa Read moreBackground Subclinical hyperthyroidism (SCH) is found to be associated with renal dysfunction. Hyperthyroidism is a well-known cause of secondary systolic hypertension. However, the effect of SCH on t...
hyperthyroidism renal function hypertension renal arterial distensibility compared significantly thyroid function mean patients = 0 sch renal vs Read moreBACKGROUND: Selenium-dependent deiodinases play a central role in thyroid hormone regulation and metabolism. In many European countries, insufficient selenium intake may consequently lead to adverse e...
hormone compared placebo function associated levels study tsh thyroid mortality selenium ft4 Read moreThe present study investigated the impact of dietary inclusion of olive cakes (OC) with or without Saccharomyces cerevisiae (SC) and citric acid (CA) on growth, digestive function, thyroid activity, a...
performance digestive function antioxidant status immunity rabbits dietary ca sc cerevisiae citric acid digestibility increased 05 < 0 diets 20 25% growth thyroid activity growing compared rabbits os20 fed oc Read moreBackground Anaplastic thyroid carcinoma(ATC) is a rare pathological type of thyroid malignancy. Primary squamous cell carcinoma of thyroid(PSCCT) is now considered as a subtype of ATC, hereinafter ref...
primary squamous cell carcinoma of... anaplastic thyroid carcinoma follicular thyroid carcinoma lymph node metastasis follicular patient cervical lymph subtype thyroid metastasis carcinoma Read moreObjectives To study the relationship between the ablation range and applied energy of laser ablation (LA) and microwave ablation (MWA) in papillary thyroid microcarcinoma (PTMC). Methods A total of 20...
papillary thyroid microcarcinoma ultrasonography microwaves laser therapy ablation techniques ht laser microwave diameter • ablation 0 r_av/e ptmc papillary thyroid microcarcinoma mwa Read moreIntroduction Atezolizumab, carboplatin, and etoposide (ACE) therapy is a standard of care for extensive-disease small cell lung cancer (SCLC); however, its safety data are scarce, limiting generalizat...
atezolizumab database study diagnosis procedure combination (d... immune-related adverse events immune checkpoint inhibitors small cell lung cancer skin disorder adjusted patients dysfunction thyroid incidence japanese aes safety cohort Read moreBackground Thyroid cancer is the most common endocrine malignancy. Current therapies are successful, however some patients progress to therapeutically refractive disease. The immunotherapeutic potenti...
azd5069 thyroid cancer cxcl8 cxcr2 receptor cxcl8 pro-tumorigenic reduced cancer thyroid human cell cells cxcr2 Read moreThe diagnosis of goiter is based on the thyroid volume measured by ultrasound in which iodine plays an important role. The purpose of this study was to evaluate the factors that affect thyroid volume ...
thyroid volume reference interval iodine bsa tsh goiter goiter china sex study bsa thyroid reference volume factors Read moreMedullary thyroid carcinoma (MTC) is a rare cancer derived from neuroendocrine C-cells of the thyroid. In contrast to other neuroendocrine tumors, a histological grading system was lacking until recen...
thyroid medullary thyroid carcinoma neuroendocrine neoplasia endocrine pathology transcriptomic dll3 signaling thyroid carcinoma high-grade dll3 mtcs Read moreBackground The risk of premature ovarian insufficiency (POI) is increased in adolescent and young adult (AYA) cancer survivors, with the prevalence depending on cancer diagnosis, treatment, and patien...
premature ovarian insufficiency hematologic cancer breast cancer thyroid cancer young adults adult adolescent leukemia breast individuals results thyroid reproductive times risk survivors ovarian unexposed premature increased insufficiency cancer Read moreInternational audience; Most marine organisms have a biphasic life cycle during which a pelagic larva is transformed into a radically different juvenile. In vertebrates the role of thyro...
thyroid hormones Read moreBackground Radioactive iodine 131 (I-131) is used in the treatment of differentiated thyroid cancer after thyroidectomy; however, its accumulation in non-thyroidal regions may give false positive resu...
epiphora dacryoscintigraphy nasolacrimal duct obstruction papillary thyroid carcinoma thyroglobulin duct uptake cancer obstruction body left nasolacrimal scan thyroid Read moreBACKGROUND: The higher prevalence of thyroid dysfunction in type 1 diabetes patients has been well established, whereas it is a matter of debate whether that is also observed in type 2 diabetes patien...
ft4 prevalence tsh basal ft3/ft4 diabetes patients thyroid levels function Read moreBackground Transient hypothyroxinemia of prematurity (THOP) is defined as a low level of circulating thyroxine (T4), despite low or normal thyroid-stimulating hormone (TSH) levels. Aims: We aimed to e...
preterm treatment thyroid systematic review severity incidence laboratory incidence decreased < 0 increased l-t4 clinical patients Read moreBACKGROUND: Kruppel-like factor 13 (KLF13) is a transcription factor and plays an important role in carcinogenesis. However, the significance of KLF13 in thyroid carcinoma (THCA) is underdetermined. I...
factor knockdown assay migration thca ifit1 carcinoma thyroid Read moreBACKGROUND: Cases of subacute thyroiditis (SAT) after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination have been reported. A human leukocyte antigen (HLA) allele, HLA-B*35, app...
fever blood pain involved pathogenesis gd hla-b*35 serum typing thyrotoxicosis revealed thyroid 01 alleles hla developed vaccination sars-cov-2 sat Read moreInternational audience; Thyroid hormones are known to trigger metamorphosis in an amphibian. This review discusses the hypothesis according to which they act in a similar manner to synch...
development thyroid Read moreBACKGROUND: Papillary thyroid carcinoma PTC is the most prevalent of all thyroid carcinomas. On the other hand, Hashimoto’s thyroiditis (HT), as part of the spectrum of autoimmune thyroid diseases, is...
pathology hashimoto compared study based thyroiditis ht ptc invasion patients tumor thyroid Read moreImmune checkpoint inhibitors (ICIs) are a revolutionary class of drugs that powerfully contribute to cancer therapy by harnessing the immune system to fight malignancies. However, their successful use...
immune checkpoint inhibitors immune-related adverse events thyroid dysfunction pathogenesis diagnosis management immune thyroid Read moreBackground Inhibitor of DNA Binding 2 (ID2) plays a crucial role in tumor cell proliferation, invasion, metastasis, and stemness. Aberrant ID2 expression is associated with poor prognosis in various c...
id2 pi3k/akt pathway emt stemness thyroid cancer cell thyroid promotes proliferation cancer id2 Read moreThyroid carcinoma, a significant yet often controllable cancer, has seen a rise in cases, largely due to advancements in diagnostic methods. Differentiated thyroid cancer (DTC), which includes papil...
cancer thyroid Read more• This study used MRI morphological features to improve College of Radiology Thyroid Imaging Reporting and Data System (ACR-TIRADS). • The performance of the improved ACR-TIRADS is superior to that of...
magnetic resonance imaging (mri) thyroid nodule diagnostic performance risk stratification american college of radiology thyr... independent 8% • missed 1% reporting imaging system data features unnecessary rate diagnosis biopsy thyroid 0 performance mri nodules malignant morphological acr-tirads 95% Read moreOBJECTIVES: This study aims to evaluate whether the use of thyroid ultrasound (US) early in the work-up of suspected thyroid disorders triggers cascade effects of medical procedures and to analyse eff...
costs analysis care test effects thyroid cluster tsh morbidity patients tests Read moreThe human voice is commonly affected by hormonal changes, both in physiological and pathological conditions. Voice changes were reported in a number of endocrine disorders, and dysphonia may be the in...
voice vocal fold endocrine disorders thyroid pituitary hormonal Read morePeople with mild to borderline intellectual disabilities face many barriers toward their sexual health. To promote sexual health and overcome these barriers, they need individualized forms of sexualit...
intellectual disabilities support staff relatives sexual health concept mapping the netherlands clusters disabilities sexuality education support health Read moreBackground To demonstrate the technical feasibility of percutaneous nephrolithotomy (PCNL) guided by 5G-powered robot-assisted teleultrasound diagnosis system (RTDS) in a complex kidney-stone (CKS) co...
intraoperative tele-assistance 5g technology robot-assisted teleultrasound diagnosis system complex kidney stones percutaneous nephrolithotomy tele-assistance Read moreAbstract Vascular endothelial cells are equipped with numerous specialized granules called Weibel-Palade bodies (WPBs). They contain a cocktail of proteins that can be rapidly secreted (3–5 min) into ...
stec-hus weibel-palade bodies von willebrand factor p-selectin ttp endothelial cells endothelial cells phase diarrhea abstract platelets ultralarge vwf Read moreThis chapter illustrates dietary strategies in the treatment of fecal incontinence. Although some foods must be excluded, the proportion of macronutrients should remain unchanged. One important strate...
diet fecal incontinence fodmaps healthy foods carbohydrates lipids foods incontinence fecal Read morePurpose Diagnostic ureteroscopy (dURS) is optional in the assessment of patients with upper tract urothelial carcinoma (UTUC) and provides the possibility of obtaining histology. Methods To evaluate e...
biopsy cytology kss upper tract urothelial cancer ureteroscopy high-grade high-risk low-grade stage 9% utuc patients disease biopsy Read moreIntroduction Abscess of the bladder wall is a rare urological disorder, with a few cases recorded in the literature. The finding of a bladder wall mass via computed tomography (CT) imaging in a visiti...
case report bladder wall abscess bladder abscess benign bladder tumour bladder wall Read moreBackground To summarize the efficacy of combined robot-assisted laparoscopy and ureteroscopy in treating complex ureteral strictures. Methods Eleven patients underwent combined robot-assisted laparosc...
ureteral strictures robot-assisted surgery ureteroscopy surgical technique end-to-end anastomosis complex end-to-end strictures patients ureteral stricture robot-assisted laparoscopy Read morePurpose We aimed to determine the prognostic value of α-hydroxybutyrate dehydrogenase (α-HBDH) in upper tract urothelial carcinoma (UTUC) patients after radical nephroureterectomy (RNU). Materials and...
α-hydroxybutyrate dehydrogenase upper tract urothelial carcinoma radical nephroureterectomy biomarker outcome value survival css utuc α-hbdh Read moreContexte En tant que l’une des protéines les plus critiques de la voie de signalisation JAK/STAT, Janus kinase 2 (JAK2) est impliquée dans de nombreux processus biologiques et maladies. Plusieurs étud...
erectile dysfunction jak2 mendelian randomization dysfonction érectile jak2 randomisation mendélienne dysfonction érectile jak2 randomisation mendélienne relationship causale relation jak2 erectile dysfunction = 0 dysfonction érectile Read moreBackground Kidney involvement frequently occurs in systemic lupus erythematosus (SLE), and its clinical manifestations are complicated. We profiled kidney involvement in SLE patients using deep learni...
systemic lupus erythematosus kidney involvement profiling deep learning national database designated incurable diseases clinical antibody data using patients involvement kidney manifestations Read moreAustralia has seen a significant rise in the use of Robotic-Assisted Surgery (RAS), with general surgery being the fastest-growing field in this technology. The proportion of general surgical RAS has ...
robotic assisted surgery education surgical education and training australia australia Read morePurpose of Review This review explores the literature that currently exists regarding quality of life for patients with spina bifida and assesses screening tools available for practitioners to assess ...
spina bifida quality of life outcomes quality of life surveys neurogenic bladder patients spina bifida domains life Read moreIntroduction and hypothesis Childbirth remains an important risk factor for the development of pelvic floor disorders, regardless of the mode of delivery. To accurately assess these symptoms, accurate...
pelvic floor disorders labor questionnaires epidemiology assessment postpartum 0 disorders online floor pelvic assessed women Read moreBladder cancer stem cells (BCSCs) are considered as the root cause of BC initiation and recurrence, and exosomes derived from BCSCs (CSCs-exo) are the vital tool for establishing a stable tumor microe...
cancer stem cell bladder cancer exosome mir-105-5p gpr12 bladder cancer cell invasion cells bc gpr12 mir-105-5p Read morePurpose To develop and validate a micro-ultrasound risk score that predicts the likelihood of significant prostate cancer in the anterior zone. Methods Patients were enrolled from three expert institu...
micro-ultrasound prostate biopsy prostate cancer transitional zone readers 0 prostate micro-ultrasound score anterior Read moreRobot-assisted thoracic surgery (RATS) for higher stages non-small cell lung carcinoma (NSCLC) remains controversial. This study reports the feasibility of RATS in patients with stages IIB–IVA NSCLC. ...
robot-assisted thoracic surgery non-small lung carcinoma higher stages locally advanced video-assisted thoracic surgery iib–iva lung resection rats study rate conversion stages nsclc Read moreBackground Diabetic nephropathy (DN) is the leading cause of end-stage renal disease, with an increasing prevalence worldwide, but its pathomechanisms remain incompletely understood. Accumulating evid...
immunity diabetic nephropathy bibliometric visual analysis research trends future journal countries dn publications trends analysis immunity bibliometric citations research Read moreBackground Acute kidney injury (AKI) is a globally critical issue. Most studies about AKI have been conducted in limited settings on perioperative or critically ill patients. As a result, there is lit...
acute kidney injury population-based cohort risk factors incidence results 0 study associated incidence Read morePurpose To compare the perioperative outcomes of L-RPLND, R-RPLND and O-RPLND, and determine which one can be the mainstream option. Methods We retrospectively reviewed medical records of 47 patients ...
laparoscopic surgery open surgery robotic surgery testicular cancer retroperitoneal lymph node dissect... 14 cell blood laparoscopic robotic complications rplnd Read morePurpose The solid-state Thulium laser (Tm: YAG) is a novel alternative to the widely used Holmium laser for endoscopic enucleation of the prostate (EEP) due to its relatively high peak power. The aim ...
benign prostate hyperplasia (bph) endoscopic enucleation of the pros... holmium laser enucleation of the p... thulium laser enucleation of the p... endoscopic reported cdc laser patients yag complications tm solid-state pulsed enucleation Read moreBackground Controversy persists regarding the superiority of partial nephrectomy (PN) versus radical nephrectomy (RN) in pT2a renal cell carcinoma (RCC) tumors. In this study we aimed to compare survi...
kidney neoplasms partial nephrectomy radical nephrectomy renal cell carcinoma survival analysis nephrectomy pt2a tumors renal postoperative survival Read moreIt is documented that Hispanic/Latinx kidney stone formers have inferior health-related quality of life (HRQoL) compared to the general population. We hypothesized that socioeconomic factors drive HRQ...
wisconsin quality of life question... quality of life nephrolithiasis urolithiasis health disparities latinx hispanic disparities differences analysis = 0 quality life patients formers insurance Read moreBorna disease (BD), a frequently fatal neurologic disorder caused by Borna disease virus 1 (BoDV-1), has been observed for decades in horses, sheep, and other mammals in certain regions of Europe. The...
veterinary borna virus disease bodv-1 Read moreDue to the frequent use of veterinary drugs in animal husbandry, it is important to know their environmental behavior. In this context, little attention has been paid to the stability of the active in...
days trimethoprim −1 mg stability antibiotics veterinary sulfadiazine amoxicillin Read moreSIMPLE SUMMARY: Biosecurity advice is an important way veterinarians can help farmers to reduce disease burdens on their farms. Many different factors are at play when delivering this advice, one bein...
perceptions veterinary advice biosecurity private veterinarians project 0 Read moreAntibiotic resistance is a global public health concern that could lead to millions of deaths if nothing is done. As a One Health problematic, it needs to be addressed both in human, an...
changes veterinary barrières resistance secteur distribution changement médicament participative chaîne vétérinaire participatory pratiques codévelopper reduce chicken avons antibiotic identifié chain utilisation au identified farms acteur·rices barriers élevages réduire filière stakeholders regulations étude value study farmers production strategies stratégies antibiotiques solutions vietnam Read moreSIMPLE SUMMARY: Antibiotic resistance is a global health crisis faced by humanity. In response to this crisis, in 2018, China released the National Pilot Work Program for Action to Reduce the Use of V...
reduce strains veterinary pilot typing antimicrobial drug drugs reduction broiler types hebei Read moreSIMPLE SUMMARY: Veterinary care of companion animals, particularly dogs and cats, continues to advance, with some companion animals receiving a standard of care equal to or exceeding that of human pat...
veterinary avc review companion ethical improved Read moreSIMPLE SUMMARY: Transferrin receptor one (TFR-1), recognized by ferritin, is overexpressed in many tumor cells. This feature has been exploited to produce a selective overload of drugs within tumor ce...
vitro drug nanocage study tumors animal engineered compared veterinary cells mammary expression tfr-1 Read moreAntimicrobial resistance is an increasingly widespread phenomenon that is of particular concern because of the possible consequences in the years to come. The dynamics leading to the resistance of mic...
veterinary drug resistance Read moreBACKGROUND: Periodontal disease remains one of the dog’s most common health issues, even though it is largely preventable by tooth brushing. Implementation of daily tooth brushing would not only impro...
dogs study results information practices dental home care health nurses veterinarians owners regarding dog veterinary Read moreObjective. To explore the availability of veterinary pharmacy didactic and experiential learning opportunities in US pharmacy programs. Methods. A 23-item questionnaire was sent to subscribers of the ...
offering veterinary programs opportunities experiential Read moreSIMPLE SUMMARY: Chymase is a protease stored in mast cell granules and is released triggered by tissue, especially cardiovascular, damage. Many studies showed the potentials of measuring chymase activ...
veterinary study pda cardiac disease alacepril activity plasma Read moreSIMPLE SUMMARY: Cats are the most popular companion animals in New Zealand. Many owners form close relationships with their cats and these relationships, along with other factors in cat owners’ lives,...
veterinarians veterinary cats cat end-of-life themes decisions owners Read moreSIMPLE SUMMARY: Veterinary care of companion animals, particularly dogs and cats, continues to advance, with some companion animals receiving a standard of care equal to or exceeding that of human pat...
veterinary avc review companion ethical improved Read moreInternational audience; The vital alliance that Pasteur formed with the veterinary profession played a defining role at the time when he became interested in animal diseases. Diseases af...
louis aux schools écoles vétérinaires veterinary time scientific médecine société bouley vétérinaire pasteur Read moreSIMPLE SUMMARY: This report describes how to apply the combination of 3D scanning, computer-aided design (CAD), and 3D printing to make a protective device for rescuing wild animals. In recent years, ...
animals veterinary freshwater report printing turtle technology wild 3d Read moreSIMPLE SUMMARY: Selective dry cow therapy involves giving local antibiotic treatment into the udder only to those cows which are likely to be infected with a mastitis-causing organism, while uninfecte...
dairy udder staff culling study veterinary training application cows dried teat period mastitis Read moreBackground Traumatic brain injury (TBI) is a common condition in veterinary medicine that is difficult to manage.Veterinary regenerative therapy based on adipose mesenchymal stem cells seem to be an e...
traumatic brain injury adipose-derived mesenchymal stem c... therapy microglia attenuating inflammation veterinary cells brain injury traumatic microglia stem mesenchymal ad-mscs tbi canine Read moreThe rise of antibiotic-resistant bacteria is among the biggest challenges in human and veterinary medicine. One of the major factors that contributes to resistance is use of frontline clinical antibio...
bacteria mrsp veterinary penicillin bacteriocins resistance Read moreSIMPLE SUMMARY: Parasitic infections are a significant problem in veterinary medicine, and their management requires an in-depth understanding of the parasite life cycle, host-parasite interactions, a...
methods veterinary medicine diagnosis knowledge control infections resistance antiparasitic diseases animal türkiye veterinarians study survey Read moreBACKGROUND: There is a growing interest in exploring the nature of communication in veterinary medicine and understanding how veterinary practitioners communicate with their clients and other professi...
communicate studies practitioners field clients agendas veterinary skills communication training Read moreThe Staphylococcus pseudintermedius group (SIG) is an emerging threat in veterinary medicine, particularly methicillin-resistant (MRSP) isolates, which are frequently associated with multidrug resista...
maldi-tof mrsp veterinary isolates antimicrobial Read moreBACKGROUND: The aim of our study was to analyse the influence of air temperature and implemented veterinary measures on salmonellosis incidence in the Czech Republic (CZ). METHODS: We conducted a desc...
1998–2017 czech annual cz influence significant veterinary measures salmonellosis Read moreSIMPLE SUMMARY: Canine Leishmaniosis is a chronic and potentially fatal disease, caused by Leishmania infantum, a zoonotic microorganism. In economically disadvantaged regions, costs associated with l...
tests protein performed veterinary practitioners owners long-term follow-up restraints clinical Read moreUnderstanding the distribution, antimicrobial resistance (AMR), and risk factors associated with multidrug-resistant (MDR) and methicillin-resistant staphylococci (MRS) isolated from cats admitted to ...
clinic 5% admitted aureus pseudintermedius saudi arabia cat factors associated isolates risk cats methicillin-resistant veterinary mdr staphylococcus spp Read moreSIMPLE SUMMARY: Despite developments in animal welfare science regarding perioperative pain management in calves (Bos taurus), there are concerns that current knowledge has not been adopted in practic...
zealand despite management perceptions veterinary current pain calves perioperative Read moreBACKGROUND: Autoimmune IgG response has been described in the pathogenesis of asthma in adults, but IgE autoimmunity has been little explored. Considering high levels of blood eosinophils and immunogl...
response adults children eosinophil ige autoantibodies epx Read moreINTRODUCTION: Dupilumab is the first biologic agent used to clinically treat moderate and severe atopic dermatitis (AD) and is currently the only biologic agent used for this condition. Many studies h...
moderate-to-severe facial atopic dupilumab dermatitis treatment patients Read morePURPOSE: In chronic spontaneous urticaria (CSU), autoimmune thyroid disease is the most common autoimmune comorbidity, and many CSU patients have immunoglobulin (Ig)E or IgG autoantibodies to thyroid ...
responses elevated and/or disease igg csu autoantibodies ige anti-tpo Read moreBackground: Animal allergies are common, with reactions ranging from rhinoconjunctivitis from respiratory exposure to anaphylaxis, usually from animal bites. Since animal bites are also common, this r...
bite Read moreBACKGROUND: In previous studies, several asthma phenotypes were identified using clinical and demographic parameters. Transcriptional phenotypes were mainly identified using sputum and bronchial cells...
gene using clinical clusters phenotypes asthma blood cluster Read moreINTRODUCTION: To date, the role of standard asthma care in reducing asthma-related health services use (HSU) during the COVID-19 pandemic remains unclear. This study examined the impact of guideline-b...
7% health increase 9% ci 95% 0 pandemic ed 0% total asthma prr polyclinic covid-19 Read morePURPOSE: Asthma is a clinical syndrome with various underlying pathomechanisms and clinical phenotypes. Genetic, ethnic, and geographic factors may influence the differences in clinical presentation, ...
severe mean cohorts respectively asthma corea proar clinical sarp lowest Read moreBACKGROUND: Mepolizumab, the first widely available anti-interleukin 5 biologic, targets eosinophilic inflammation and has been shown in clinical trials to reduce exacerbations, oral corticosteroid de...
costs eosinophilic clinical exacerbations study visits severe outcomes mepolizumab 0 healthcare 001 real-world patients asthma-related Read moreBACKGROUND: Bronchial thermoplasty (BT) is an interventional endoscopic treatment for severe asthma leading to the clinical improvement, but morphologic changes of bronchial wall related to the proced...
decreased changes related response improvement severe mm 003 clinical p=0 patients bronchial asthma 0 Read moreIntroduction: Nickel and cobalt were not regarded as pertinent contact allergens in the hairdressing trade for the last decades. It was even stated that the relevance of nickel allergy in the hairdres...
allergens hairdressers metallic tools hairdressing cobalt nickel contact Read moreINTRODUCTION: Allergen distribution has obvious geographical characteristics. Understanding local epidemiological data may provide evidence-based strategies for the prevention and management of diseas...
species shanghai sex allergen Read morePURPOSE: Asthma is associated with a high prevalence of psychopathological disorders, especially depressive disorders or anxiety. In patients with uncontrolled severe asthma, monoclonal antibody (mAb)...
disorder mdd/gad burden mab antibody patients mab-therapy therapy disorders severe asthma response anxiety symptoms using Read moreThe novel coronavirus disease of 2019 (COVID-19) pandemic has severely impacted the training of health care professional students because of concerns of potential asymptomatic transmission to colleagu...
Read moreINTRODUCTION: Spitz nevi (SN) include a wide range of benign melanocytic nevi, which are controversial due to their morphologic resemblance to melanoma (MM). AIM: To describe dermoscopic and reflectan...
confocal dermoscopy reflectance dermoscopic features mm pattern atypical Read moreINTRODUCTION: Psoriasis is a T cell-mediated polygenic chronic inflammatory disease. Interleukin (IL)-17A plays a major role in psoriasis pathogenesis. Secukinumab is a high-affinity human monoclonal ...
moderate ua 0 decreased pasi severe 05 glucose psoriasis secukinumab vulgaris liver metabolism tretinoin serum Read moreMastocytosis or an elevated basal serum tryptase (bST) level are known risk factors for patients with insect venom allergy. We report on 3 patients with a history of severe anaphylactic insect sting r...
insect venom elevated patients Read moreBACKGROUND: The extent of differences between genetic risks associated with various asthma subtypes is still unknown. To better understand the heterogeneity of asthma, we employed an unsupervised meth...
associated reduced normallf asthma genetic function lung reducedlf clusters late‐onset Read moreBACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic impacted various parts of society, including Japanese children with allergies. OBJECTIVE: This study investigated risk factors for pediatri...
parents allergens children school comments dermatitis total disease pandemic covid-19 factors home pediatric allergies Read moreThis study aimed to evaluate the prevalence and risk factors of mental disorders in patients with chronic urticaria (CU) in a cohort of adult outpatients. Mental disorders occurred in almost one-sixth...
risk factors Read morePURPOSE: Repeated exposure to platinum compounds increases the risk of immunoglobulin E-mediated immediate hypersensitivity reactions (HSR). To date, many different desensitization protocols with vary...
team interdisciplinary protocols desensitization hsrs Read moreBACKGROUND: Increased medication adherence leads to better asthma control and health outcomes. However, many studies have found that patient adherence to maintenance medication is poor. AIM: We undert...
adherence qualitative studies perspectives review asthma health medication findings Read moreBACKGROUND: With ongoing COVID-19 vaccination schedules and the popularity of cosmetic fillers, it is important to examine and record associated adverse reactions to a more general audience of health ...
diagnosis reactions treatment vaccination reaction Read moreAsthma is an important health concern in Latin America (LA) where it is associated with variable prevalence and disease burden between countries. High prevalence and morbidity have been observed in so...
poor health environmental disease asthma factors research Read moreBACKGROUND: Atopic dermatitis (AD) is a chronic inflammatory skin disease that affects children and adults. Poor treatment adherence in AD requires interventions to promote self-management; patient ed...
scoping studies review education Read moreBACKGROUND: Both revision surgery and omalizumab are recommended therapies for the treatment of recurrent chronic rhinosinusitis with nasal polyps (CRSwNP) and can improve patients' clinical symptoms ...
study snot-22 clinical crswnp qol improvements months treatments total treatment recurrent patients revision surgery symptoms omalizumab 0 Read moreWe use cookies and other similar technologies to:
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