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ExploreThe research axis proposed in this multidisciplinary thesis opens up on various methodologies in the field of innovation in sound design in the fields of applied arts and object design....
projet objet object indian [cs méthodologie avons social science [info box patients tala alzheimer sound design Read moreThis study aimed to develop new equations to estimate cardiorespiratory fitness specifically for older adults and, secondly, to analyze the associations of cardiorespiratory fitness, both objectively ...
alzheimer cognitive impairment physical fitness aerobic capacity aging adults associated tests measured objectively set cardiorespiratory estimated cognitive Read moreInternational audience; The exact neuropathological mechanism by which dementia process unfolds is under intense scrutiny. The disease affects about 38 million people worldwide, 70% of w...
functional alzheimer connectivity Read moreAlthough Alzheimer's disease (AD) cannot be reversed or cured, timely diagnosis can significantly reduce the burden of treatment and care. Current research on AD diagnosis models usually regards the...
resources strategy care current medical task alzheimer learning settings model diagnostic diagnosis Read moreLarge-scale brain networks undergo widespread changes with older age and in neurodegenerative diseases such as Alzheimer's disease (AD). Research in young adults (YA) suggest that the underlying funct...
emn correlated architecture alzheimer organization brain fc tau networks ad network memory rest adults Read moreBackground This systematic review synthesizes the most recent neuroimaging procedures and machine learning approaches for the prediction of conversion from mild cognitive impairment to Alzheimer’s dis...
systematic review alzheimer mild cognitive impairment prediction neuroimaging machine learning neuroimaging systematic Read moreINTRODUCTION: The Alzheimer's Disease Neuroimaging Initiative (ADNI) aims to validate biomarkers for Alzheimer's disease (AD) clinical trials. To improve generalizability, ADNI4 aims to enroll 50‐60% ...
ad clinical disease alzheimer urps adni4 participants Read moreBackground Scrub typhus is a mite-borne infectious rickettsial disease that can occur in rural and urban areas, with an especially high prevalence in older populations. This disease causes systemic va...
scrub typhus tsutsugamushi dementia alzheimer cohort population-based alzheimer’s using study ratio time control dementia incidence history disease Read moreAmyloid-beta 42 (Aβ42) and phosphorylated tau (pTau) levels in cerebrospinal fluid (CSF) reflect core features of the pathogenesis of Alzheimer's disease (AD) more directly than clinica...
fluid cerebrospinal levels loci tau alzheimer disease Read moreGenerative approaches for cross-modality transformation have recently gained significant attention in neuroimaging. While most previous work has focused on case-control data, the application of gene...
networks alzheimer generative Read moreInternational audience; Background: Alzheimer's disease (AD) and Korsakoff's syndrome (KS) are two major neurocognitive disorders characterized by amnesia but AD is degenerative while KS...
mb mtt patients controls volumes hippocampus damaged cortex thalamic nuclei patient ks ad korsakoff disease alzheimer syndrome cingulate Read moreBackground A decline in episodic memory is one of the earliest cognitive characteristics of Alzheimer disease and memory tests are heavily featured in cognitive composite endpoints that are used to de...
episodic memory cognition composite scores plasma biomarkers alzheimer disease baseline biomarkers composite decline ptau217 tests included longitudinal recall alzheimer disease plasma memory cognitive paragraph Read moreINTRODUCTION: Emerging evidence has shown that the glucagon-like peptide-1 (GLP-1) agonist can be used to treat Alzheimer disease; however, knowledge of its neural targets is limited. To understand th...
diencephalon related age-related alzheimer’s brainstem gene decline decade age alzheimer patchy significant immunoreactivity hippocampus brain cortical glp-1 cortex human glp-1r peptide-1 Read moreIn this paper, a comprehensive review on Alzheimer's disease (AD) is carried out, and an exploration of the two machine learning (ML) methods that help to identify the disease in its initial stages. A...
alzheimer's disease early detection convolution neural network mri images machine learning densenet169 vgg19 3d cnn positron emission tomography eresidual softmax regression adni network cnn ad sets 18-layer convolutional research data disease alzheimer machine learning methods Read moreIntroduction Alzheimer’s disease is a neurocognitive disorder that affects elderly people by slowly impaired cognition, dementia, and gets worse with age. It slowly impacts the quality of life. Clinic...
aducanumab alzheimer’s disease β-amyloid cholinesterase inhibitors dementia cognitive dysfunction early-onset alzheimer’s disease inflammation late-onset alzheimer’s disease n-methyl-d-aspartate neurodegeneration neurofibrillary tangles memory neurocognitive disorders senile plaques tau proteins alzheimer Read moreInternational audience; Age, sex and APOE-ε4 genotype have been identified as the strongest predictors of the risk of developing Alzheimer's Disease (AD). This work models the pathologic...
disease genotype alzheimer sex Read moreAlzheimer's disease prognosis is critical for early Mild Cognitive Impairment patients for timely treatment to improve the patient's quality of life. Whilst existing prognosis techniques demonstrate...
disease model data alzheimer prognosis based hgib Read moreAlzheimer's disease (AD) cannot be reversed, but early diagnosis will significantly benefit patients' medical treatment and care. In recent works, AD diagnosis has the primary assumption that all ca...
alzheimer diagnosis ad abnormal pattern Read moreAlzheimer's disease is a degenerative brain disease. Being the primary cause of Dementia in adults and progressively destroys brain memory. Though Alzheimer's disease does not have a cure currently,...
disease computer brain alzheimer Read moreMultimodal medical data (e.g. MR and PET imaging, CSF measurements, clinical assessments) reflect different aspects of Alzheimer's Disease, including early changes in brain structure an...
multimodal ad alzheimer feature stages disease cognitive Read moreSynaptic loss is intrinsically linked to Alzheimer's disease (AD) neuropathology and symptoms, but its direct impact on clinical symptoms remains elusive. The postsynaptic protein Shank3 (SH3 and mult...
synaptic 3xtg-ad δex4-9 brain human levels months disease alzheimer age shank3 shank3a mice ad cognitive neuropathology symptoms Read moreDementia incidence increases steadily with age at rates that may vary across racial groups. This racial disparity may be attributable to polygenic risk, as well as lifestyle and behavioural factors. W...
95% ci sex-adjusted model hr factors effect 001 polygenic dementia alzheimer’s sex alzheimer disease score incidence 0 scores all-cause race Read moreBackground Feature selection is often used to identify the important features in a dataset but can produce unstable results when applied to high-dimensional data. The stability of feature selection ca...
ensemble feature selection stability data-driven thresholding alzheimer's disease stability relevant feature features selection alzheimer selectors threshold disease data-driven Read moreBrain development and maturation leads to grey matter networks that can be measured using magnetic resonance imaging. Network integrity is an indicator of information processing capacity which decline...
alzheimer changes disease axonal integrity loss Read moreEarly detection of Alzheimer's disease's precursor stages is imperative for significantly enhancing patient outcomes and quality of life. This challenge is tackled through a semi-supervised multi-mo...
introduce multi-modal alzheimer hypergraph Read moreIntroduction Amyotrophic lateral sclerosis (ALS) is an inevitably fatal condition that leads to a progressive loss of physical functioning, which results in a high psychosocial burden and organization...
amyotrophic lateral sclerosis caregiver burden palliative care quality of care motor neuron disease psychosocial care pwals Read moreBackground There is a lack of effective therapeutic strategies for amyotrophic lateral sclerosis (ALS); therefore, drug repurposing might provide a rapid approach to meet the urgent need for treatment...
amyotrophic lateral sclerosis mendelian randomization drug repurposing druggable gene tbk1 resp18 targets gene [or 95%ci 0 amx drug pharmacological r788 tnfsf12 identified repurposing tbk1 als gpx3 analysis druggable Read moreAmyotrophic lateral sclerosis (ALS) can result into an incomplete locked in state (iLIS), in which communication depends on eye tracking computer devices. Oculomotor function impairments in ALS have b...
amyotrophic lateral sclerosis eye movements oculomotor function eye tracking communication systems... executive function saccades advanced eye stronger latencies patients oculomotor ilis als Read moreBackground Studies have reported that a noncoding hexanucleotide repeat in C9ORF72 , is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) among Cau...
amyotrophic lateral sclerosis frontotemporal dementia gene variant familial sporadic variant spectrum als variants als-ftd chinese Read moreAim The study aims to increase understanding of edaravone’s efficacy and safety as an amyotrophic lateral sclerosis (ALS) treatment and provide significant insights regarding this field’s future resea...
edaravone als amyotrophic lateral sclerosis meta-analysis 95% safety efficacy edaravone Read moreObjective There is increasing evidence that amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease impacting large-scale brain networks. However, it is still unclear which stru...
amyotrophic lateral sclerosis white matter dti network connectomics machine learning psychoradiology = 0 healthy using motor = 2 structural disease als patients baseline rate Read moreBackground Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease affecting over 300,000 people worldwide. It is characterized by the progressive decline of the nervous system that leads t...
amyotrophic lateral sclerosis als peripheral lateral sclerosis pls burden testing rare-variant analyses based antxr2 disease model variant collapsing significant gene pls analyses Read moreBackground and objective The neuropathology of amyotrophic lateral sclerosis (ALS) follows a regional distribution pattern in the brain with four stages. Using diffusion tensor imaging (DTI), this pat...
amyotrophic lateral sclerosis diffusion tensor imaging motor neuron disease magnetic resonance imaging clinical score als-frs-r progression healthy pattern dti size patient controls categorized sequential effect tracts als-frs-r Read moreBackground Despite being a useful strategy for providing respiratory support to patients with advanced or terminal illnesses, non-invasive ventilation (NIV) requires in-depth investigation in several ...
non-invasive ventilation palliative care bibliometrics vosviewer citespace cancer amyotrophic lateral sclerosis specialized palliative care palliative non-invasive ventilation care key studies analysis Read moreBackground Although percutaneous endoscopic gastrostomy (PEG) offers better access to the gastrointestinal system, in patients with previous abdominal surgery, PEG can be unsuccessful. Laparoscopicall...
gastrostomy laparoscopic surgery amyotrophic lateral sclerosis remnant performed stomach percutaneous patients gastrostomy Read moreThere is considerable variability in disease progression for patients with amyotrophic lateral sclerosis (ALS) including the age of disease onset, site of disease onset, and survival time. There is gr...
genetic marker structural variant amyotrophic lateral sclerosis clinical trials participant selection enrichment tool responder sub-population clinical markers trials als Read moreAmyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease affecting the brain and spinal cord motor neurons. On 25 April 2023, the drug tofersen, an antisense oligonucleotide, received ...
amyotrophic lateral sclerosis selenium selenium compounds sod1 tofersen gene sod1 administration drug disease selenium tofersen Read moreA central event in the pathogenesis of motor neuron disease (MND) is the loss of neuromuscular junctions (NMJs), yet the mechanisms that lead to this event in MND remain to be fully elucidated. Mainte...
amyotrophic lateral sclerosis als neuromuscular junction musk agrin motor neurons acetylcholine receptors patients muscle mnd Read moreObjective To employ Artificial Intelligence to model, predict and simulate the amyotrophic lateral sclerosis (ALS) progression over time in terms of variable interactions, functional impairments, and ...
amyotrophic lateral sclerosis clinical trajectories prognosis modelling population model artificial intelligence dynamic bayesian networks als tool predict Read moreNeurological disorders (NDs) are characterized by progressive neuronal dysfunction leading to synaptic failure, cognitive impairment, and motor injury. Among these diseases, Alzheimer's disease (AD), ...
mitochondria fibroblasts cell reprogramming alzheimer's disease parkinson’s disease huntington’s disease amyotrophic lateral sclerosis mitochondrial dysfunction strategy neurological patients abnormalities fibroblasts disorders dysfunction mitochondrial als Read moreBackground When a patient arrives in the emergency department following a stroke, a traumatic brain injury, or sudden cardiac arrest, there is no therapeutic drug available to help protect their jeopa...
stroke traumatic brain injury sudden cardiac arrest concussion modeling migraine ischemia na/k pump huntington's disease alzheimer's disease amyotrophic lateral sclerosis ketamine penumbra persistent vegetative state dendritic beading brain swelling neurons brain glutamate blood sd Read moreAmyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the progressive degeneration of both upper and lower motor neurons. A defining histopathological feature in ap...
amyotrophic lateral sclerosis als motor neuron disease non-motor symptoms patients clinical neurons non-motor symptoms als Read moreAmyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease affecting the brain and spinal cord motor neurons. On 25 April 2023, the drug tofersen, an antisense oligonucleotide, received ...
amyotrophic lateral sclerosis selenium selenium compounds sod1 tofersen gene sod1 administration drug disease selenium tofersen Read moreBackground Amyotrophic lateral sclerosis (ALS) is a highly debilitating neurodegenerative condition. Despite recent advancements in understanding the molecular mechanisms underlying ALS, there have be...
statistical analysis plan randomized double-blind clinical trial phase iii amyotrophic lateral sclerosis bile acids 2019 trial treatment analysis Read moreBackground and objective The neuropathology of amyotrophic lateral sclerosis (ALS) follows a regional distribution pattern in the brain with four stages. Using diffusion tensor imaging (DTI), this pat...
amyotrophic lateral sclerosis diffusion tensor imaging motor neuron disease magnetic resonance imaging clinical score als-frs-r progression healthy pattern dti size patient controls categorized sequential effect tracts als-frs-r Read moreAmyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by selective, early degeneration of motor neurons in the brain and spinal cord. Motor neurons have long axo...
cytoskeleton neurofilament mitochondria amyotrophic lateral sclerosis neurodegeneration axonal transport gut microbiome neurons mitochondrial cytoskeletal Read moreBackground Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease affecting over 300,000 people worldwide. It is characterized by the progressive decline of the nervous system that leads t...
amyotrophic lateral sclerosis als peripheral lateral sclerosis pls burden testing rare-variant analyses based antxr2 disease model variant collapsing significant gene pls analyses Read moreProtein homeostasis, or proteostasis, is essential for cell function and viability. Unwanted, damaged, misfolded and aggregated proteins are degraded by the ubiquitin–proteasome system (UPS) and the a...
proteostasis proteasome autophagy alzheimer’s disease huntington’s disease parkinson’s disease amyotrophic lateral sclerosis aging cancer protein Read moreBackground Amyotrophic lateral sclerosis (ALS) is a devasting neurodegenerative disorder for which no successful therapeutics are available. Valproic acid (VPA), a monocarboxylate derivative, is a kno...
amyotrophic lateral sclerosis monocarboxylate transporter 1 sodium-coupled monocarboxylate tra... neuroprotection valproic acid mt lines monocarboxylate uptake wt vpa als Read moreBackground Amyotrophic lateral sclerosis (ALS) is a lethal neurodegenerative disease characterized by the gradual loss of upper and lower motor neurons that leads to progressive muscle atrophy and wea...
edaravone amyotrophic lateral sclerosis adverse effect safety mean study als edaravone patients Read moreBACKGROUND: Polygenic risk score (PRS) has been demonstrated to be effective in identifying individuals at high risk of developing cancer, but its prognostic value remains unclear. METHODS: We constru...
findings score site-specific overall css polygenic cancer = 0 risk survival meta hr Read moreSIMPLE SUMMARY: Around thirty-five percent of pancreatic cancer patients present with locally advanced pancreatic cancer. These patients are treated with chemotherapy, and sometimes (stereotactic)radi...
immuno-modulatory chemotherapy lapc investigate body treatment immune imm-101 cancer pancreatic Read moreIntroduction Oligometastatic disease (OMD) is a metastatic stage that could benefit maximally from local therapies. Patients in this state have a better prognosis relative to those with disseminated m...
neoplasm metastasis metastasis directed therapy oligometastasis sabr cell received squamous os novo oligometastatic pfs survival cancer omd stereotactic radiotherapy patients Read moreIn the context of pancreatic cancer, surgical intervention is typically recommended for localized tumours, whereas chemotherapy is the preferred approach in the advanced and/or metastatic setting. How...
pancreatic cancer older patient chemotherapy geriatric assessment spanish treatment pancreatic cancer Read moreThe coupling between mechanical forces and modulation of cell signalling pathways is essential for tissue plasticity and their adaptation to changing environments. Whilst the number of physiological a...
erk egfr mechanics mechanotransduction morphogenesis growth signalling self-organisation cancer link signalling erk Read moreCervical cancer is an important health problem and it is considered the fourth most lethal women's cancer worldwide. The intertumoral T cell pool is exposed in a number of immunosuppressive pathways. ...
cancer cervical Read moreBackground Granulomatosis with polyangiitis (GPA) is characterized by necrotizing granulomatous inflammation with necrotizing vasculitis predominantly affecting small to medium vessels. The survival r...
carcinoma case report granulomatosis with polyangiitis lung cancer older patients gpa cancer lung Read moreBACKGROUND: With the availability of health insurance claim data, pharmacovigilance for various drugs has been suggested; however, it is necessary to establish an appropriate analysis method. To detec...
classified prognosis effect patients level atc study colorectal cancer Read morePurpose Due to the increase in both cancer incidence and overall survival rates, more adolescents and young adults (AYAs) have to live with the effects that their cancer diagnosis and following treatm...
cancer adolescents and young adults lived experience qualitative research interpretative phenomenological an... bodily experience effects study Read moreBackground In pancreatic cancer, systemic treatment options in addition to chemotherapy remain scarce, and so far only a small proportion of patients benefit from targeted therapies. Objective The pat...
discussed challenges kras cohort patients molecular cancer treatment board tumor pancreatic targeted Read morePurpose The outcome of the sentinel lymph node in breast cancer patients affects adjuvant treatment. Compared to conventional histopathology, analysis by one-step nucleic acid amplification (OSNA) har...
breast cancer sentinel lymph node biopsy one-step nucleic acid amplificatio... adjuvant treatment art breast alnd histopathology data 9% < 0 detected patients difference treatment histology 14 adjuvant cancer analysis sentinel axillary osna Read moreBackground Surveillance mammography is recommended annually for early detection of disease relapse among breast cancer survivors; yet Black women have poorer national rates of surveillance mammography...
surveillance mammography breast cancer survivors socioeconomic status health disparities status guidelines adherence compared study health non-metropolitan 12 months living mammogram mammography cancer black surveillance survivors breast women Read morePurpose Despite clear evidence-based supporting a benefit to exercise on physical and psychological metrics in patients with cancer, recruitment to exercise trials amongst cancer survivors is suboptim...
recruitment rate recruitment strategies cancer survivors exercise review survivorship current survivors exercise recruitment cancer trials rates Read moreBreast cancer is a significant public health concern and is the leading cause of cancer-related deaths among women. Despite advances in breast cancer treatments, medication non-adherence remains a m...
language cancer breast effects information media social Read moreThe MYC proto-oncogene ( MYC ) is one of the most frequently overexpressed genes in breast cancer that drives cancer stem cell-like traits, resulting in aggressive disease progression and poor prognos...
traits stem aggressive migration cancer znf148 myc cell Read moreThe Polycomb repression exerts transcriptional control by two distinct complexes, PRC1 AND PRC2. This epigenetic control is ensured by H2AK119ub1 and H3K27me3 deposition. The polycomb r...
genes epigenetic activity étude gènes study cours polycomb poisson zèbre ezh2 au développement modèle model cancer development ezh1 chez complexes zebrafish répression repression prc2 Read moreBackground: Prostate cancer is the most common malignancy among men worldwide, and its diagnosis and treatment are challenging due to its heterogeneity.Methods: Integrating single-cell RNA sequencing ...
bulk oxidative energy rna stress cancer prostate mxra8 Read moreBACKGROUND: The early detection and diagnosis of cancer to reduce avoidable mortality and morbidity is a challenging task in primary health care. There is a growing evidence base on how to enable earl...
researchers suggestions cancer research diagnosis primary Read moreIntroduction: Cases of throat cancer are rising worldwide. With survival decreasing significantly at later stages, early detection is vital. Artificial intelligence (AI) and machine learning (ML) ha...
using binary articles detecting speech classification review cancer throat Read morePurpose Bladder cancer (BCa) is one of the most common malignant tumors in the urogenital system, characterized by the high recurrence rate, mortality rate and poor prognosis. Based on cuproptosis-rel...
bladder cancer cuproptosis lncrna prognosis immune response data signature cancer immune bca tumor prognosis Read moreCombination therapy as an important treatment option for lung cancer has been attracting attention due to the primary and acquired resistance of chemotherapeutic drugs in the clinical application. In ...
time-restricted feeding cisplatin lung cancer mrna sequence p53 cisplatin combination a549 cell lung cancer a549/ddp trf cells ddp Read moreColorectal carcinoma is the third most common type of cancer. Although the role of matricellular proteins and their association with tumor progression is well documented, limited data are available co...
cancer epithelial-mesenchymal transition expression proteins colorectal cyr61 Read moreMelanoma is one of the most aggressive forms of skin cancer, causing a large proportion of skin cancer deaths. However, melanoma diagnoses by pathologists shows low interrater reliability. As melano...
melanoma image cancer learning melanocytic cell computer science Read moreThe current standard for detecting human epidermal growth factor receptor 2 (HER2) status in breast cancer patients relies on HER2 amplification, identified through fluorescence in situ hybridizatio...
pipeline learning available slides fish cancer test status her2 Read moreBACKGROUND: Peripherally inserted central catheters (PICCs) are common vascular access devices inserted for adults undergoing intravenous treatment in the community setting. Individuals with a PICC re...
cancer understanding inserted participants picc information living Read moreThis paper presents a novel control strategy for drone networks to improve the quality of 3D structures reconstructed from aerial images by drones. Unlike the existing coverage control strategies fo...
camera function drone control Read moreThis paper presents the methodology and key results which enabled to establish the so-called Ancillary Service Matrix (ASM) presenting the ability to deliver the different ancillary services of each...
results plant demonstrator storage ancillary power matrix services hydro Read moreTerrain information is a crucial factor affecting the performance of unmanned aerial vehicle (UAV) networks. As a tutorial, this article provides a unique perspective on the completeness of terrain ...
networking study uav terrain Read moreWith the development of legal intelligence, Criminal Court View Generation has attracted much attention as a crucial task of legal intelligence, which aims to generate concise and coherent texts tha...
legal egg extraction intelligence generation events method Read moreProving geometric theorems constitutes a hallmark of visual reasoning combining both intuitive and logical skills. Therefore, automated theorem proving of Olympiad-level geometry problems is conside...
proving solves geometry 30 solved methods method Read moreRobots that assist humans in their daily lives should be able to locate specific instances of objects in an environment that match a user's desired objects. This task is known as instance-specific i...
robotics Read moreLarge language models are aligned to be safe, preventing users from generating harmful content like misinformation or instructions for illegal activities. However, previous work has shown that the a...
backdoors language competition report Read moreHolographic near-eye displays are a promising technology to solve long-standing challenges in virtual and augmented reality display systems. Over the last few years, many different computer-generate...
parallax near-eye holographic Read moreNatural language interfaces to embodied AI are becoming more ubiquitous in our daily lives. This opens further opportunities for language-based interaction with embodied agents, such as a user instr...
Read morePre-trained models have become pivotal in enhancing the efficiency and accuracy of time series forecasting on target data sets by leveraging transfer learning. While benchmarks validate the performa...
transfer bias learning source similarity diversity forecasting Read moreIn this paper, we study algebraic geometry codes from curves over $\mathbb{F}_{q^\ell}$ through their virtual projections which are algebraic geometric codes over $\mathbb{F}_q$. We use the virtual ...
geometry fractional algebraic Read moreWe introduce a fragment of second-order unification, referred to as \emph{Second-Order Ground Unification (SOGU)}, with the following properties: (i) only one second-order variable is allowed, and (...
second-order Read moreMachine-learning models, which are known to accurately predict patterns from large datasets, are crucial in decision making. Consequently, counterfactual explanations-methods explaining predictions ...
method Read moreState-of-the-art performance in QA tasks is currently achieved by systems employing Large Language Models (LLMs), however these models tend to hallucinate information in their responses. One approac...
attribution accuracy Read moreIn reinforcement learning, robust policies for high-stakes decision-making problems with limited data are usually computed by optimizing the \emph{percentile criterion}. The percentile criterion is ...
constructing policies sets ambiguity percentile criterion Read moreHuman behavior modeling is important for the design and implementation of human-automation interactive control systems. In this context, human behavior refers to a human's control input to systems. ...
modeling human systems behavior control Read moreLarge language models (LLMs) can adapt to new tasks through in-context learning (ICL) based on a few examples presented in dialogue history without any model parameter update. Despite such convenien...
based speech probability icl bycs inverse selection example examples in-context inference science computer Read moreImplicit neural representations (INR) suffer from worsening spectral bias, which results in overly smooth solutions to the inverse problem. To deal with this problem, we propose a universal framewor...
implicit representations neural inverse science computer Read moreThis paper proposes a GeneraLIst encoder-Decoder (GLID) pre-training method for better handling various downstream computer vision tasks. While self-supervised pre-training approaches, e.g., Masked ...
pre-trained computer task-specific various generalist pre-training tasks vision Read moreAn $\mathsf{F}_{d}$ upper bound for the reachability problem in vector addition systems with states (VASS) in fixed dimension is given, where $\mathsf{F}_d$ is the $d$-th level of the Grzegorczyk hi...
science computer algorithm Read moreThe last two years have seen a rapid growth in concerns around the safety of large language models (LLMs). Researchers and practitioners have met these concerns by introducing an abundance of new da...
improving evaluating language datasets safety Read moreMost deep learning models in medical imaging are trained on adult data with unclear performance on pediatric images. In this work, we aim to address this challenge in the context of automated anatom...
trained ct pediatric Read moreFederated learning aims to tackle the ``isolated data island" problem, where it trains a collective model from physically isolated clients while safeguarding the privacy of users' data. However, sup...
client supervised science zero-shot lightweight training federated learning data computer Read moreInherent ambiguity in layout annotations poses significant challenges to developing accurate 360{\deg} room layout estimation models. To address this issue, we propose a novel Bi-Layout model capabl...
model ambiguous ambiguity layout Read moreIntegrated sensing and communication (ISAC) has already established itself as a promising solution to the spectrum scarcity problem, even more so when paired with a reconfigurable intelligent surfac...
optimization destructive Read moreIntroduction The COVID-19 pandemic period (2020 to 2022) challenged and overstretched the capacity of primary health care services to deliver health care globally. The sector faced a highly uncertain ...
healthcare access covid first nations people aboriginal people clinic use policies pandemic delivery information community health primary staff regional remote care communities Read moreThe global pandemic due to emergence of COVID 19 has created the unrivaled public health crisis. It has huge morbidity rate never comprehended in the recent decades. Researchers have made many effor...
covid 19 potential inhibitors Read moreBackground Since the declaration of COVID-19 as a pandemic in 2020, its main symptoms have primarily affected the respiratory system. However, it also presents other systemic manifestations, including...
covid delta & omicron variant laryngopharyngeal manifestations patients study primarily paralysis fold exhibited laryngo pharyngeal covid-19 vocal related affection Read moreBackground Seeking and obtaining effective health care for Long COVID remains a challenge in the USA. Women have particularly been impacted, as they are both at higher risk of developing Long COVID an...
long covid women qualitative post covid access to care quality of care 30 seen care women symptoms clinic experiences covid Read moreBackground Public transportation plays a major role in the transmission of SARS-CoV2, the virus that causes COVID-19, due to the confined spaces in vehicles. It is therefore very crucial to apply COVI...
covid-19 public transportation public transport operators covid-19 preventive measures study risk eastern uganda epidemic aware included interviews participants awareness perceptions public transportation covid-19 perceived covid passengers barriers operators challenges 19 preventive transmission transport measures Read moreMore than three years after the start of the COVID-19 pandemic, individuals are frequently reporting multiple COVID-19 infections. However, these reinfections remain poorly understood. Here, we invest...
findings electronic patients characterize following epoch million record study health initial individuals infection reinfection severe reinfections covid-19 covid Read moreLong COVID is characterized by persistent symptoms, particularly pulmonary impairment, which necessitates advanced imaging for accurate diagnosis. Hyperpolarised Xenon-129 MRI (XeMRI) offers a promi...
covid alignment data multimodal registration Read moreLateral flow tests (LFTs) enable rapid, low-cost testing for health conditions including Covid, pregnancy, HIV, and malaria. Automated readers of LFT results can yield many benefits including empowe...
results vlms dataset covid test Read moreBackground Seeking and obtaining effective health care for Long COVID remains a challenge in the USA. Women have particularly been impacted, as they are both at higher risk of developing Long COVID an...
long covid women qualitative post covid access to care quality of care 30 seen care women symptoms clinic experiences covid Read moreThe global pandemic due to emergence of COVID 19 has created the unrivaled public health crisis. It has huge morbidity rate never comprehended in the recent decades. Researchers have made many effor...
covid 19 potential inhibitors Read moreIt is well known the potential of severe acute respiratory coronavirus type 2 (SARS-CoV-2) infection to induce post-acute sequelae, a condition called Long COVID. This syndrome includes several sympto...
cns covid-19 plasma = 0 neurocognitive covid pnfl Read moreZang et al. use RECOVER EHR data to study Long COVID risk factors and apply mathematical modeling to predict the development of long COVID conditions. They find that severe acute SARS-CoV-2 infection,...
modeling pulmonary covid conditions factors predict develop associated risk acute Read moreBACKGROUND: It is unknown if early COVID-19 monoclonal antibody (mAb) therapy can reduce risk of Long COVID. The mAbs amubarvimab/romlusevimab were previously demonstrated to reduce risk of hospitaliz...
36 reduce week covid covid-19 outcome placebo amubarvimab/romlusevimab Read moreBACKGROUND: Long covid (post covid-19 condition) is a complex condition with diverse manifestations, uncertain prognosis and wide variation in current approaches to management. There have been calls f...
patients complex individual reasoning clinics quality condition guidelines evidence-based improvement covid Read moreBackground Seeking and obtaining effective health care for Long COVID remains a challenge in the USA. Women have particularly been impacted, as they are both at higher risk of developing Long COVID an...
long covid women qualitative post covid access to care quality of care 30 seen care women symptoms clinic experiences covid Read morePurpose This longitudinal study investigated distress rates in patients with advanced ovarian cancer during the COVID-19 pandemic and examined whether time, illness representations, and coping strateg...
ovarian cancer distress fear of progression coping perceptions covid advanced levels patients cancer ovarian coping Read moreBACKGROUND: Severe COVID and multisystem inflammatory syndrome (MIS-C) are characterized by excessive inflammatory cytokines/chemokines. In adults, disease severity is associated with SARS-CoV-2-speci...
pediatric bulk adults spike inflammatory fc igg following vaccination adult covid glycosylation Read moreINTRODUCTION: The relationship between SARS-CoV-2 viral dynamics during acute infection and the development of long COVID is largely unknown. METHODS: A total of 7361 asymptomatic community-dwelling p...
study times infection development load associated ci covid sars-cov-2 acute 0 arr 95% viral Read moreThe global pandemic due to emergence of COVID 19 has created the unrivaled public health crisis. It has huge morbidity rate never comprehended in the recent decades. Researchers have made many effor...
covid 19 potential inhibitors Read morePURPOSE: Long COVID brain fog is often disabling. Yet, no empirically-supported treatments exist. This study’s objectives were to evaluate feasibility and efficacy, provisionally, of a new rehabilitat...
treatment pilot findings rct randomized cognitive covid adults iadl immediate-cict tau cict brain fog Read moreLateral flow tests (LFTs) enable rapid, low-cost testing for health conditions including Covid, pregnancy, HIV, and malaria. Automated readers of LFT results can yield many benefits including empowe...
results vlms dataset covid test Read moreLateral flow tests (LFTs) enable rapid, low-cost testing for health conditions including Covid, pregnancy, HIV, and malaria. Automated readers of LFT results can yield many benefits including empowe...
results vlms dataset covid test Read moreObjective: We present a simple parameter, calculated from a single wearable sensor, that can be used to objectively measure disease severity in people with myalgic encephalomyelitis/chronic fatigue ...
measure healthy steps/day controls subjects objective disease severity covid 0 $\mathbf{p Read moreTelogen effluvium is characterized by excessive hair shedding usually following a stressful event. Ferritin has been used in clinical practice as a biomarker of nonanemic iron deficiency in cases of t...
covid postcovid telogen effluvium ferritin biomarkers vitamin d vitamin c zinc lactoferrin ivermectin azithromycin significantly biomarker study ferritin patients value Read moreObjective To examine the relationship between physical rehabilitation parameters including an approach to quantifying dosage with hospital outcomes for patients with critical COVID-19. Design Retrospe...
physical rehabilitation early mobilization critical illness occupational therapy physical therapy covid outcomes care < 0 am-pac covid-19 physical hospital 001 Read moreWe conducted a programmatic, observational cohort study with mother-infant pairs (MIPs) enrolled in prevention-of-mother-to-child-transmission (PMTCT) programs in Malawi to assess the feasibility and ...
child development hiv maternal-child health services delivery of health care integrated sub-saharan africa malawi malawi development 12 months six integrating outcomes infants mips programs comparison pmtct ecd mothers Read moreBACKGROUND: Long-term engagement in HIV care is essential to achieving and maintaining viral suppression. Adolescents living with HIV (ALHIV) experience many barriers to remaining engaged in care and ...
hiv months ci 15–19 initiated adolescents 95% windhoek analysis care art Read moreBackground In Malawi, approximately 25% of adolescents living with HIV (ALWH) also suffer from depression. Not only is HIV stigma a major contributor to depression but it also adversely impacts HIV ca...
stigma discrimination adolescents hiv depression malawi faced outcomes care discrimination health impacts alwh social depression Read moreBackground Human immunodeficiency virus (HIV) infection is associated with an elevated incidence of cervical cancer, and accelerated disease progression, but the underlying mechanisms are not well und...
hiv infection gp120 protein tat protein epithelial–mesenchymal transition ... cervical cancer progression genes revealed cervical hiv pathway cancer patients proteins Read moreBackground The Joint United Nations Programme on HIV/AIDS launched the 90-90-90 initiative. Failure to meet the target reflects the difficulties in successfully implementing HIV treatment policy. Ther...
influencing stakeholders environmental individual availability hiv implementation ghana training policy treatment Read moreINTRODUCTION: Paediatric HIV and sickle cell disease (SCD) are two stigmatising and potentially fatal illnesses that place a significant burden on families. HIV patients benefit from a longstanding fr...
adolescents children paediatric p=<0 patients hiv quality life caregivers scd 95% 001 Read moreYoung adults with perinatally acquired HIV (PAH) face numerous challenges, including antiretroviral therapy (ART) adherence, managing onward HIV transmission risks and maintaining wellbeing. Sharing o...
hiv disclosure perinatal feasibility intervention adults study feasibility p = 0 follow-up pah participants hiv uk uganda intervention Read moreThe aim of this study was to explore risk factors for hearing loss or affecting hearing function in adults living with HIV. A quantitative cross-sectional design was employed. A non-probability purpos...
adults hiv risk factors middle ear pathologies 95%ci living adults p-value = 0 factors risk hearing Read moreBackground Within the African region, there are an estimated 8 million people living with HIV (PLHIV) in South Africa. Seeking healthcare services from traditional healers (TH) is one of the alternati...
hiv utilisation older people traditional healers health service research factors healthcare africa clinic 05 plhiv th 0 study [aor = 0 ci utilisation people south Read moreMillions lost their lives for HIV/AIDS while many more live with the virus with significantly compromised degree of quality of life. Women are more affected than men because of various contributing fa...
hiv infection pregnant women determinant factors amhara regional state ethiopia participants conducted aor = 0 women 0 ci study 95% hiv associated status factors syphilis pregnant education Read moreOBJECTIVES: Infectious syphilis has been proposed as an indication for HIV pre-exposure prophylaxis (PrEP) in women. We explored how many women experienced HIV seroconversion after being diagnosed wit...
load prep viral evidence ontario hiv positive syphilis women test Read moreGlobally, People Who Inject Drugs (PWID) have limited healthcare, treatment, and prevention services, and they frequently experience stigma and negative attitudes toward healthcare providers when acce...
people who inject drugs treatment hiv mozambique hiv services people pwid Read moreInternational audience; BACKGROUND: The use of long acting injectable (LAA) antiretroviral drugs may be an alternative option for HIV treatment and prevention. Our study focused on patie...
hiv prep prevention study laa treatment Read moreBACKGROUND: In Guangdong Province, China, there is lack of information on the HIV epidemic among high-risk groups and the general population, particularly in relation to sexual transmission, which is ...
china approximately model epidemic accounted transmission 2016 guangdong province infections hiv women cri 95% msm 0% Read moreINTRODUCTION: Antiretroviral therapy (ART) and TB preventive treatment (TPT) both prevent tuberculosis (TB) disease and deaths among people living with HIV. Differentiated care models, including commu...
8% increasing hiv trial incidence 3% ten art range mortality 36 9% 0% tpt tb care Read moreWe created a brief version of The Index, a validated patient-reported measure that has potential to quickly identify patients at risk for poor retention. We analyzed Index scores from 2406 patients fr...
hiv patients brief index Read moreBackground In 2020, almost 20% of people living with HIV (PLHIV) in Morocco are still unaware of their HIV status. Under these circumstances, HIV self-test (HIVST) can be an efficient additional tool ...
hiv self-testing vulnerable populations acceptability feasibility usability morocco salivary alcs self-testing self-test rapid test morocco hiv participants fsw testing acceptability sex usability hivst msm Read moreInternational audience; Abstract Background Coverage of HIV testing remains sub-optimal in West Africa. Between 2019 and 2022, the ATLAS program distributed ~400 000 oral HIV self-tests ...
factors associated users reach hivst aor 0 vs testing [0 education hiv first-time distribution testers Read moreBackground Long-acting injectable formulations for HIV infection have been approved and are now available in Japan. Although not currently recommended as first-line drugs in Japanese or overseas guide...
antiretroviral therapy patient satisfaction people living with hiv long-acting injectable hiv patient included art study oral medications daily therapy drugs injectable long-acting Read moreSouth African adolescents with perinatally-acquired HIV (APHIV)—teenagers who were born with HIV—lack access to sexual and reproductive health (SRH) education specific to their HIV status. Ineffective...
adolescent health sex education hiv global health mhealth gender sexuality reproductive health attitudes information teenagers skills srh intsha mhealth education aphiv hiv africa participants health sexual intervention reported knowledge peers behaviors Read moreBackground Treatment of latent tuberculosis infection (LTBI) is effective in preventing progression to TB disease. This study aimed to synthesize available evidence on the efficacy, adherence, and saf...
systematic review network meta-analysis tuberculosis preventive therapy contact ltbi included 3hp tpt incidence efficacy safety 6h 3rh hiv followed review treatment tb Read moreINTRODUCTION: HIV epidemics in Western and Central Africa (WCA) remain concentrated among key populations, who are often unaware of their status. HIV self-testing (HIVST) and its secondary distributio...
primary interviews test reported key populations users distribution partners hiv hivst Read moreBackground Tuberculosis, along with HIV, is the leading cause of mortality and morbidity globally. Despite the fact that several primary studies have been conducted on the incidence rate of tuberculos...
incidence tuberculosis hiv person sub-saharan africa sub-saharan 100 study review using antiretroviral factors person-years ci tuberculosis 95% rate incidence therapy hiv ahr = 1 studies pooled patients systematic africa hiv-infected people meta-analysis Read moreUsing multiple pharmacies has been linked to negative outcomes including increased inappropriate drug use, toxicity, and mortality, yet up to half of all patients in the US use multiple pharmacies. A ...
pharmacy hiv stigma safety single pharmacy spu ls multiple pharmacies hiv Read moreIntroduction Antiretroviral medication coverage remains sub-optimal in much of the United States, particularly the Sothern region, and Non-Hispanic Black or African American persons (NHB) continue to ...
hiv antiretroviral therapy pre-exposure prophylaxis modeling race largest declines msm incidence art nhb increased women reduce epidemic hiv art/prep Read moreThe population < 60 years of age is also affected by a significant disease burden from seasonal influenza. It carries a high economic burden, mainly driven by influenza-associated productivity losses ...
influenza eiadaptation weiterentwickelter influenzaimpfst... real-world-daten impfempfehlung influenza egg adaptation enhanced influenza vaccine real-world data vaccination recommendation egg-based von burden conventional population eine vaccines der influenzaimpfstoffe influenza Read moreInternational audience; Influenza A/H5N1 has circulated in Asia since 2003 and is now enzootic in many countries in that region. In Cambodia, the virus has circulated since 2004 and has ...
clade differences circulated ferrets virulence ducks influenza 1c infections transmission mesh viruses humans virus Read moreOBJECTIVES: Pregnant women are at increased risk of complications from influenza, and infants are at increased risk of pertussis. Maternal influenza and Tdap (tetanus, diphtheria, and acellular pertus...
pertussis survey risk maternal hcp influenza live birth women pregnancy Read moreBACKGROUND: The (H1N1)pdm09 live attenuated influenza vaccine (LAIV) strain was changed for the 2017–2018 influenza season to improve viral fitness, following poor protection against (H1N1)pdm09 virus...
9% virus respectively age h1n1 pdm09 laiv positivity shedding influenza 2017–2018 Read moreIntroduction For pregnant women, vaccination with inactivated influenza vaccine (IIV) and tetanus, diphtheria, acellular pertussis vaccine (Tdap) is recommended. In Peru, uptake is nonetheless low. A ...
coverage knowledge maternal immunization influenza pertussis tetanus peru vaccine tdap pregnant health conducted practices attitudes immunization recommended peru women knowledge vaccination pregnant/postpartum Read moreBackground Healthcare workers (HCWs) were the priority group for influenza vaccination, in China during the 2020/2021 and 2021/2022 influenza seasons. However, vaccination rates in HCWs have always be...
influenza healthcare worker vaccination coverage internet-based survey china 2022 chinese vaccine vaccinated policy influenza free 2020/2021 coverage 2021/2022 vaccination hcws 05 < 0 Read moreInternational audience; A (H9N2) avian influenza A viruses were first detected in Uganda in 2017 and have since established themselves in live bird markets. The aim of this study was to ...
[sdv markets sciences isolates influenza viruses uganda h9n2 Read moreInternational audience; Influenza D virus (IDV) has been detected in bovine respiratory disease (BRD) outbreaks, and experimental studies demonstrated this virus's capacity to cause lesi...
antibodies cattle virus respiratory influenza samples Read moreOBJECTIVE: Nosocomial transmission of influenza is a major concern for infection control. We aimed to dissect transmission dynamics of influenza, including asymptomatic transmission events, in acute c...
symptoms swabs individuals influenza-positive secondary attack hcws days study clinic participants symptomatic medicine inpatients transmission 5% asymptomatic influenza Read moreBACKGROUND: This study assessed the differences in daily virus reduction and the residual infectivity after the recommended home stay period in Japan in patients infected with influenza and treated wi...
detected study emergence reduction virus daily viral influenza pa japan na using variants ba os Read moreBackground The influenza viruses pose a threat to human health and medical services, and vaccination is an important way to prevent infection. However, the effectiveness of influenza vaccines is affec...
influenza influenza vaccine vaccine effectiveness immune response immunogenicity conditions rates chronic a/h1n1 < 0 affecting history vaccines response influenza associated factors human b/victoria vs Read moreInternational audience; ABSTRACT The latest outbreaks of high pathogenicity avian influenza viruses (HPAIVs) were the most widespread ever seen in Europe, entailing considerable economi...
albumin serum health [sdv sciences hpaiv results bovine surveillance bsa influenza protocol avian rt-qpcr Read moreBACKGROUND: Over the past decade, influenza surveillance has been established in several African countries including Zambia. However, information on the on data quality and reliability of established ...
acceptability quality iss improvements funds attribute obtained evaluation score surveillance 0 influenza performance Read moreChina has a huge population with respiratory diseases, these diseases should be managed well in primary care, however, primary care physicians’ knowledge level of these diseases were unknown. The aim ...
physicians’ 7% 1% china diseases respiratory physicians 0% cap care primary knowledge asthma influenza Read moreINTRODUCTION: Influenza infection in the United States results in hundreds of thousands of hospitalizations and 12,000 to 60,000 yearly deaths. Influenza season sees a sharp increase in emergency depa...
barriers failure deaths ed-based military department emergency implementation influenza ed programs vaccination Read moreBACKGROUND: Influenza causes a substantial burden worldwide, and current seasonal influenza vaccine has suboptimal effectiveness. To develop better, more broadly protective vaccines, a more thorough u...
target infections 95% results virus influenza duration shortened illness antibodies adults associated shedding Read moreBACKGROUND: We sought to determine if racial differences in influenza vaccination among nursing home (NH) residents during the 2008–2009 influenza season persisted in 2018–2019. METHODS: We conducted ...
percentage level vaccination influenza nh residents Read moreBACKGROUND: Our study aimed to assess the safety and protective effect of maternal influenza vaccination on pregnancy and birth outcomes. METHODS: The study population comprised 1253 healthy nulliparo...
pregnancy low safety effect study ci 95% ahr maternal vaccination protective birth influenza Read moreBackground In recent years, accumulating evidences have revealed that influenza A virus (IAV) infections induce significant differential expression of host long noncoding RNAs (lncRNAs), some of which...
influenza virus (iav) long noncoding rna (lncrna) 5-methylcytosine (mc) modification... methylated rna immunoprecipitation... a549 cells a549 host h1n1 differentially influenza modifications expression virus iav lncrnas m^5c Read moreInternational audience; Background: Cardiorespiratory decompensation (CRD) visits have a profound effect on adult emergency departments (EDs). Respiratory pathogens like respiratory sync...
etienne emergency departments influenza grenoble saint spearman predaflu increased ed respiratory bronchiolitis visits outbreak chu population eds adult pediatric crd Read moreBackground Sleep apnea is associated with chronic comorbidities and acute complications. Existing data suggest that sleep apnea may predispose to an increased risk and severity of respiratory tract in...
sleep apnea lower respiratory tract infections... pneumonia influenza multimorbidity incidence comorbidities increased matched controls respiratory tract lower risk apnea sleep Read moreThis dataset was developed for the following article: Rogan PK, Mucaki EJ and Shirley BC. A proposed molecular mechanism for pathogenesis of severe RNA-viral pulmonary infections [version 1; peer re...
pl srsf1 ri human position table information rnps1 transcriptome-wide provide using values histograms hiv-1 matrices data specified strains radiation script minimum bit strands clustertodripseqanalysisprogram models exceed doubling anemia aplastic host nucleotide rna-viral mechanism pulmonary contain severe pathogenesis indicate elements proposed square appear infections plots influenza tracks clusters viral – sites distance intersite information-dense png hnrnpa1 file cluster brackets lollipop matrix convention drip- plot tables naming 0 rsequence [two time multiple exome molecular analysis virus site binding genome threshold rna intervals sars-cov-2 coronavirus detailed dripc-seq transcriptome strand gene Read moreThe generation time, representing the interval between infections in primary and secondary cases, is essential for understanding and predicting the transmission dynamics of seasonal influenza, includi...
incubation influenza time period transmission data Read moreBACKGROUND: There are concerns about a link between the ChAdOx1 nCoV-19 and Ad26.COV2.S vaccines against COVID-19 and cerebral venous thrombosis (CVT) and other thrombotic events. One key missing comp...
vaccine mrna p = 0 vaccines matched pvt influenza patients thrombosis diagnosis cvt people cohort 95% ci Read moreHighly pathogenic avian influenza viruses (HPAIVs) cause severe disease and high fatality in poultry (1) . They emerge exclusively from H5 and H7 low pathogenic avian influenza viruses (LPAIVs) (2) . ...
avian pathogenic nucleotide hemagglutinin insertion transient rna viruses influenza Read moreBackground Listeria monocytogenes are Gram-positive rods, which are the etiological factor of listeriosis . L. monocytogenes quickly adapts to changing environmental conditions. Since the main source ...
acid stress heat stress nutrition stress osmotic stress cold stress freezing-defrosting stress factors rods survival concentration monocytogenes stress food 0% growth Read moreIntroduction Laccase is a copper-containing polyphenolic oxidase widely found in bacteria, archaea, fungi, animals, and plants. As a green biocatalyst with considerable potential for numerous environm...
bacterial laccase chloride tolerance dye decolorization redox mediator potential halomonas alkaliantartica effect activity lacha laccase Read moreBackground Circadian rhythms, observed across all domains of life, enable organisms to anticipate and prepare for diel changes in environmental conditions. In bacteria, a circadian clock mechanism has...
circadian rhythm circadian clock diurnal cycle diel cycle oscillations symbiosis gut microbiota microbiota diel gut bacteria rhythms mechanisms host circadian Read moreBackground Fusarium Head Blight (FHB) is a destructive floral disease of different cereal crops. The Ascomycete fungus Fusarium graminearum ( Fg ) is one of the main causal agents of FHB in wheat and ...
fusarium head blight fungal transformation target site integration complementation secretion coleoptiles wheat confocal microscopy genome sequence region ectopic cassettes transformation developed tsi locus fusarium integration Read moreBackground The emergence of multidrug-resistant (MDR) Escherichia coli strains poses significant challenges in clinical settings, particularly when these strains harbor New Delhi metallo-ß-lactamase (...
multidrug-resistant ... carbapenems resistance ... incf plasmid st167 novel multidrug-resistant coli genetic plasmid resistance pndm-5-0083 Read moreThere has been considerable research into the understanding of the healthy skin microbiome. Similarly, there is also a considerable body of research into whether specific microbes contribute to skin d...
atopic dermatitis epidermis bacteria skin microbiome fluorescent in situ hybridisation performed found controls patients epidermal epidermis surface Read moreBackground The emergence of multi-resistant pathogens have increased dramatically in recent years, becoming a major public-health concern. Among other promising antimicrobial molecules with potential ...
ciliophora genome mining antimicrobial peptide bioprospection defensins Read moreBackground Harmonia axyridis is an effective natural enemy insect to a variety of phloem-sucking pests and Lepidopteran larvae, such as aphids, scabies, and phylloxera, while its industrial production...
firmicutes proteobacteria synergistic substance intestinal abundance glucose composition axyridis aphid basic microbiota gut artificial Read moreEmerging fungal pathogens are a global challenge for humankind. Many efforts have been made to understand the mechanisms underlying pathogenicity in bacteria, and OMICs techniques are largely responsi...
emerging pathogens genome evolution extremophiles rna-seq antifungals fungal fungi resistance pathogens genomes scedosporium Read moreBackground Sahiwal cattle is an indigenous cattle breed of Pakistan and mastitis is one of the major problems faced by Sahiwal cattle which hinders its production potential. The study was designed to ...
sahiwal cattle milk microbiota 16s rrna metagenomics cattle diversity muciniphila akkermansia compared microbiota sahiwal clinical milk subclinical dominant Read moreThis study investigated the influence of bacterial cyclic lipopeptides (LP; surfactins, iturins, fengycins) on microbial interactions. The objective was to investigate whether the presence of bacteria...
bacillomycin d lipopeptide (lp) abundance co-inoculation fos biological control microbial interaction. fungal growth microbial gb03 fzb42 bacterial lp strains Read moreDermatophytes and other members of Onygenales are unique in their ability to degrade keratin, affecting hair and nails, and in the case of human hosts, causing skin infections. Subtillisins are essent...
hair keratin trichophyton species sub1 eif2ak4 hairs hair dermatophytes Read moreBackground In our continuing search for biologically active natural enemies from North of Africa with special reference to Tunisian fungi, our teamwork screened fungi from different ecological habitat...
choline dehydrogenase endochitinase ovicidal phylogeny scuf egypt tunisia observation exposure eggs sp javanica study sem Read moreBackground There is a link between Helicobacter pylori (HP) infection and small intestinal bacterial overgrowth (SIBO) with nonspecific digestive symptoms. Nonetheless, whether HP infection is associa...
small intestinal bacterial overgro... proton pump inhibitor gastrointestinal symptoms meta-analysis p < cochrane 95% meta-analysis heterogeneity subgroup related ^ 0 infection hp sibo Read moreAmong molecular-based techniques for fungal identification, Sanger sequencing of the primary universal fungal DNA barcode, the internal transcribed spacer (ITS) region (ITS1, 5.8S, ITS2), is commonly ...
internal transcribed spacer (its) targeted long-read sequencing nanopore technology fungal identification datasets using classified reads vsearch study analysis pipeline region sequencing species candida n = 1 fungal Read moreAntimicrobial peptides, such as bacteriocin, produced by probiotics have become a promising novel class of therapeutic agents for treating infectious diseases. Selected lactic acid bacteria (LAB) isol...
antibacterial activity bacteriocin-like inhibitory substa... biofilm formation multidrug-resistant bacteria probiotic antibacterial genome aeruginosa strains blis cylb30 cylb47 Read moreThe genus Cyathus was established in 1768, but more in-depth taxonomic studies with the group only occurred after 1844. In the following years, changes in the infrageneric classification of Cyathus we...
gasteromycetes its-lsu analysis infrageneric classification based classification infrageneric species cyathus Read moreThe fungi in Glomeromycota are mutualistic symbionts of plant roots and produce a special glycoprotein called “glomalin” on their spores and mycelium cell wall. The glomalin enters adjacent soil after...
arbuscular mycorrhizal fungi climate change glomalin soil carbon pool fungi carbon Read moreBackground Bacillus thuringiensis (Bt) is a gram-positive ubiquitous saprophytic bacterium that produces proteins (Crystal protein, Vegetative insecticidal protein, and Secreted insecticidal protein) ...
insecticidal proteins s whole genome sequencing strain b... assam thuringiensis virulence protein strain identity mh753362 isolated novel genome genes insecticidal mh753363 Read moreThe biological mechanisms underlying meat quality remain unclear. Currently, many studies report that the gastrointestinal microbiota is essential for animal growth and performance. However, it is unc...
tan sheep gut microbiota metagenomics 16s rdna sheep c12 0 including microbiota meat quality gastrointestinal Read moreBackground Over time, the amount of germs resistant to antibacterial medications has been steadily rising because of their prolonged and indiscriminate use. The increase in drug resistance significant...
antibacterial activity microorganism mechanism of action polysaccharide isolation purification activity Read moreAbstract Fucose is a deoxyhexose sugar present and studied in mammals. T