Todos los días presentamos para usted los estudios científicos del momento
ExplorarINTRODUCTION: For many patients and caregivers, a major goal of disease-modifying treatments (DMT) for Alzheimer disease (AD) dementia is to extend independence in instrumental and basic activities of...
ad dementia disease alzheimer treatments time clinical extend cdr months Leer másInternational audience; Alzheimer's disease and related dementia (ADRD) are characterized by multiple and progressive anatomo-clinical changes including accumulation of abnormal proteins...
dementia alzheimer csf markers sequence disease cognitive latent time clinical progression Leer másAlzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and memory loss. Early detection of AD is crucial for effective intervention and treatment. In...
spontaneous alzheimer language disease pause method information speech detection ad Leer másResearchers are constantly trying to develop therapeutic targets in neurodegenerative disorders like Alzheimer's dementia and Parkinson's disease. Despite enormous endeavors, there are several unmet n...
alzheimer's disease parkinson’s disease pre-clinical gut–brain dysbiosis preclinical alzheimer Leer másBackground Caring for a person with Alzheimer’s disease is stressful for caregivers. So that, considering all the emotional and financial costs imposed on the families of Alzheimer’s patients, stress ...
stress management validity reliability psychometrics properties alzheimer results csms designed factor validity analysis patients caregivers caring care alzheimer’s family items study management stress scale Leer másThis review explains how allosteric stabilizers of γ-secretase may prevent Alzheimer’s disease by specifically exerting opposite effects as pathogenic presenilin mutations. Two phase-III clinical tria...
presenilin gamma-secretase-modulator γ-secretase allosteric stabilizer alzheimer cancer prevention mutations ad γ-secretase presenilin alzheimer’s disease Leer másBackground Mild cognitive impairment (MCI) may evolve into dementia. Early recognition of possible evolution to Alzheimer's disease (AD) and dementia with Lewy Bodies (DLB) is of importance, but actua...
lewy body dementia alzheimer dementia mild cognitive decline meta-analysis disease accuracy clinical studies markers Leer másInternational audience; The appearance of the biomarkers in body fluids like blood, urine, saliva, tears, etc. can be used for the identification of many diseases. This article aimed to ...
alzheimer diseases biomarker parkinson molecularly imprinted polymers disease biomarkers Leer másAlzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and memory loss. Early detection of AD is crucial for effective intervention and treatment. In...
spontaneous alzheimer language disease pause method information speech detection ad Leer másBackground Dementia is one of the major causes of disability and dependency among older people worldwide. The formation of an aging population in Iran can be associated with societal problems, includi...
alzheimer dementia prevalence iran systematic review meta-analysis review studies systematic 0 estimated dementia prevalence ci 95% iran Leer másInsoluble fibrillar tau, the primary constituent of neurofibrillary tangles, has traditionally been thought to be the biologically active, toxic form of tau mediating neurodegeneration in Alzheimer’s ...
alzheimer tau seeding spreading microglia propagation oligomeric compared seeding tau Leer másDeep learning methods have significantly advanced medical image segmentation, yet their success hinges on large volumes of manually annotated data, which require specialized expertise for accurate l...
alzheimer disease segmentation model Leer másAlzheimer's disease (AD) is a progressive brain disorder characterized by extracellular amyloid-β (Aβ) plaques, intracellular neurofibrillary tangles formed by hyperphosphorylated Tau p...
alzheimer glucose intolerance disease amyloid-β protein diet app/ps1 hfd neuroinflammation tau resistance insulin inflammation pathology ir Leer másAn interpretable machine learning (ML) framework is introduced to enhance the diagnosis of Mild Cognitive Impairment (MCI) and Alzheimer's disease (AD) by ensuring robustness of the ML models' inter...
interpretability diagnosis alzheimer disease machine Leer másAlzheimer's disease is a degenerative brain disease. Being the primary cause of Dementia in adults and progressively destroys brain memory. Though Alzheimer's disease does not have a cure currently,...
disease computer brain alzheimer Leer másSemantic fluency tests have been widely used as a screening test for dementia of Alzheimer type. However, few studies have explored the application of semantic fluency tests in Mandarin Chinese speake...
category scores test participants adults alzheimer fluency Leer másAlzheimer's disease is a degenerative brain disease. Being the primary cause of Dementia in adults and progressively destroys brain memory. Though Alzheimer's disease does not have a cure currently,...
disease computer brain alzheimer Leer másAutomated diagnosis of Alzheimer Disease(AD) from brain imaging, such as magnetic resonance imaging (MRI), has become increasingly important and has attracted the community to contribute many deep l...
model 2d introduce perspective alzheimer diagnosis adapt 3d Leer másAlzheimer's disease (AD) is characterized by intracerebral deposition of abnormal proteinaceous assemblies made of amyloid-β (Aß) peptides or tau proteins. These peptides and proteins i...
mutation disease alzheimer amyloid-β peptides connectivity pathology osa synaptic osaka cerebral Leer másBACKGROUND: Neuroimaging studies often quantify tau burden in standardized brain regions to assess Alzheimer disease (AD) progression. However, this method ignores another key biological process in wh...
brain metrics stages symptomatic burden amyloid preclinical participants p = 0 alzheimer ad tau spatial Leer másNearly fifty million older people suffer from neurodegenerative diseases, including Alzheimer (AD) and Parkinson (PD) disease, a global burden expected to triple by 2050. Such an imminent “neurologica...
diseases alzheimer parkinson drugs protein Leer másThe landscape of RNA isoforms in human cortex is revealed by deep long-read RNA sequencing. Determining whether the RNA isoforms from medically relevant genes have distinct functions could facilitate ...
rna alzheimer human frontal Leer másMEG are non invasive neuroimaging techniques with excellent temporal and spatial resolution, crucial for studying brain function in dementia and Alzheimer Disease. They identify changes in brain act...
alzheimer analyses based combining meg using features Leer másBACKGROUND: Alzheimer's disease (AD) is a complex multifactorial neurodegenerative disorder and the most common form of dementia. AD is highly heritable, with heritability estimates of ∼70% from twin ...
due ad/dementia knowledge genes ancestry dementia identified including alzheimer ad loci populations studies disease susceptibility genetic architecture sample gwas size Leer másThe global trend toward aging populations has resulted in an increase in the occurrence of Alzheimer's disease (AD) and associated socioeconomic burdens. Abnormal metabolism of amyloid‐β (Aβ) has been...
research aβ neuroprotective disease neurodegeneration alzheimer ad Leer másMultiple neurotoxic proteinopathies co-exist within vulnerable neuronal populations in all major neurodegenerative diseases. Interactions between these pathologies may modulate disease progression, su...
superoxide dismutase-1 tar dna-binding protein 43 p62/sqstm1 proteinopathy amyotrophic lateral sclerosis sporadic familial subcellular interactions proteins cord spinal proteinopathies neurons als tdp-43 Leer másBehavioral disorders, with an average prevalence of 30–60% are important non-motor symptoms in amyotrophic lateral sclerosis (ALS) that have a negative impact on prognosis, management and quality of l...
amyotrophic lateral sclerosis behavioral disorders apathy anxiety epidemiology neuroimaging functional connectivity biomarkers treatment options disorders current brain symptoms behavioral als Leer másMutations in FUS and TBK1 often cause aggressive early-onset amyotrophic lateral sclerosis (ALS) or a late-onset ALS and/or frontotemporal dementia (FTD) phenotype, respectively. Co-occurrence of muta...
amyotrophic lateral sclerosis als frontotemporal dementia ftd tbk1 fus phenotype tbk1 fus/tbk1 fus patients Leer másObjective To evaluate the performance of serum neurofilament light chain (NfL) and cerebrospinal fluid (CSF) phosphorylated neurofilament heavy chain (pNfH) as diagnostic biomarkers for the differenti...
neurofilaments motor neuron disease amyotrophic lateral sclerosis multifocal motor neuropathy biomarker diagnostic performance disease neuron 0 cutoff auc diagnostic neurofilaments mnd motor csf patients serum Leer másBackground Compared with typical bulbar onset amyotrophic lateral sclerosis (ALS), isolated bulbar palsy (IBP), an often under-understood variant of ALS, is characterized by symptoms confined to bulba...
bulbar palsy amyotrophic lateral sclerosis survival motor neuron prognosis survival 20 months disease onset patients ibp Leer másAmyotrophic lateral sclerosis (ALS) is an untreatable and clinically heterogeneous condition primarily affecting motor neurons. The ongoing quest for reliable biomarkers that mirror the disease status...
amyotrophic lateral sclerosis cytokines short chain fatty acids ttv virome metabolism microbiome research patient Leer másAmyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease which currently lacks effective treatments. Mutations in the RNA-binding protein FUS are a common cause of familial ALS, accoun...
amyotrophic lateral sclerosis pp2a gsk3 kinesin neurons pathogenesis als protein hyperphosphorylation ipsc-smns kinesin-1 gsk3 disease pp2a Leer másBackground and objectives Primary lateral sclerosis (PLS) is a motor neuron disease characterised by loss of the upper motor neurons. Most patients present with slowly progressive spasticity of the le...
primary lateral sclerosis amyotrophic lateral sclerosis hereditary spastic paraplegia genetics resulted pathogenic criteria als c9orf72 sclerosis lateral pls variants patients Leer másAmyotrophic lateral sclerosis (ALS) is an untreatable and clinically heterogeneous condition primarily affecting motor neurons. The ongoing quest for reliable biomarkers that mirror the disease status...
amyotrophic lateral sclerosis cytokines short chain fatty acids ttv virome metabolism microbiome research patient Leer másIntroduction The absence of nigrosome 1 on brain MRI and the hyperechogenicity of substantia nigra (SNh) by transcranial sonography are two useful biomarkers in the diagnosis of parkinsonisms. We aime...
amyotrophic lateral sclerosis primary lateral sclerosis progressive muscular atrophy hyperechogenicity of ... ultrasound nigrosome 1 lateral snh sclerosis = 0 [1 absence patients Leer másBackground Peer support is effective in improving psychological well-being of family caregivers of people with conditions such as dementia, cancer, and brain injury. However, there are limited data on...
peer support motor neuron disease amyotrophic lateral sclerosis informal caregiver e-health randomised controlled trial living people controlled randomised caregiver intervention informal primary caregivers psychological trial support scale peer Leer másBackground MRI studies reported that ALS patients with bulbar and spinal onset showed focal cortical changes in corresponding regions of the motor homunculus. We evaluated the capability of brain 2-[^...
amyotrophic lateral sclerosis positron emission tomography als hc 2-[^18f]fdg-pet set metabolic spinal bulbar pure onset ps Leer másAmyotrophic lateral sclerosis (ALS) can result into an incomplete locked in state (iLIS), in which communication depends on eye tracking computer devices. Oculomotor function impairments in ALS have b...
amyotrophic lateral sclerosis eye movements oculomotor function eye tracking communication systems... executive function saccades advanced eye stronger latencies patients oculomotor ilis als Leer másBackground The present study aimed at evaluating the diagnostic properties of the Frontal Assessment Battery (FAB) in non-demented ALS patients by addressing the Edinburgh Cognitive Behavioural ALS Sc...
frontal assessment battery amyotrophic lateral sclerosis cognitive screening executive diagnostics psychometrics predicted motor als stages administrability below-cut-off scores Leer másBiallelic pathogenic repeat expansions in RFC1 were recently identified as molecular origin of cerebellar ataxia, neuropathy, vestibular areflexia syndrome (CANVAS) as well as of one of the most commo...
repeat analysis oxford nanopore sequencing amyotrophic lateral sclerosis rfc1 mnd motor neuron disease additional clinical repeat mnd expansions rfc1 Leer másObjective To evaluate the performance of serum neurofilament light chain (NfL) and cerebrospinal fluid (CSF) phosphorylated neurofilament heavy chain (pNfH) as diagnostic biomarkers for the differenti...
neurofilaments motor neuron disease amyotrophic lateral sclerosis multifocal motor neuropathy biomarker diagnostic performance disease neuron 0 cutoff auc diagnostic neurofilaments mnd motor csf patients serum Leer másAmyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease involving both upper and lower motor neurons, leading to paralysis and eventually death. Symptomatic treatments such as i...
amyotrophic lateral sclerosis motor neurons autophagy stem cells gene editing progression therapies als Leer másMotor neuron disease (MND) is a rapidly progressive neurodegenerative disorder with limited treatment options. Historically, neurological trials have been plagued by suboptimal recruitment and high ra...
motor neuron disease amyotrophic lateral sclerosis clinical trials recruitment neuron motor questionnaires study disease factors participation recruitment trial mnd–smart n = Leer másBackground Interventional trials in amyotrophic lateral sclerosis (ALS) suffer from the heterogeneity of the disease as it considerably reduces statistical power. We asked if blood neurofilament light...
neurofilament light prediction model disease progression amyotrophic lateral sclerosis interventional trials statistical power decrease study observational score heterogeneity alsfrs-r als trial onset disease power model Leer másALCAR (Acetyl-L-carnitine) is a donor of acetyl groups and increases the intracellular levels of carnitine, the primary transporter of fatty acids across the mitochondrial membranes. In vivo studies s...
observational study treatment amyotrophic lateral sclerosis neurological disease case–control efficacy nor baseline compared treated subjects 0 Leer másBackground Amyotrophic lateral sclerosis (ALS) is characterized by a progressive loss of motor neurons (MNs), leading to paralysis, respiratory failure and death within 2–5 years of diagnosis. The exa...
neurodegeneration amyotrophic lateral sclerosis mutation... pluripotent stem cells secretome neuroprotective mice model death ipscs ipsc-cm hipscs mutation cm Leer másBackground Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease affecting over 300,000 people worldwide. It is characterized by the progressive decline of the nervous system that leads t...
amyotrophic lateral sclerosis als peripheral lateral sclerosis pls burden testing rare-variant analyses based antxr2 disease model variant collapsing significant gene pls analyses Leer másBackground Patients with amyotrophic lateral sclerosis present perioperative challenges for clinical anesthesiologists for anesthesia-associated complications. Case presentation A 54-year-old Han woma...
amyotrophic lateral sclerosis sacral plexus block dexmedetomidine case report plexus block real-time ultrasound-guided sacral lateral sclerosis amyotrophic Leer másBackground Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder with progressive motor system impairment, and recent evidence has identified the extra-motor involvement. Small fib...
amyotrophic lateral sclerosis corneal confocal microscopy small fiber neuropathy corneal nerves inferior whorl length dendritic iwdc cell involvement clinical controls lower whorl peripheral inferior als corneal neuropathy nerve iwl region patients fiber = 0 density Leer másAmyotrophic lateral sclerosis (ALS) is a neurodegenerative fatal disorder in which motor neurons within the brain and spinal cord degenerate. A single infusion of mesenchymal stem cells (MSCs) delays ...
amyotrophic lateral sclerosis mesenchymal stem cells intravenous... multiple doses quality of life deterioration function single als compared motor Leer másThe use of medicinal plants for the treatment of diseases, including cancer, is acknowledged and accepted in many African nations. Heavy metal contamination of plant materials poses a potential health...
heavy metals medicinal plants skin cancer icp-ms health risk assessment treatment cancer – plants 0 metal health medicinal Leer másBackground Complete mesocolic excision (CME) or D3 lymphadenectomy led to survival benefits for locally advanced right colon cancer, but with vague definitions in anatomy and debated surgical hazard i...
d3 + cme complete mesocolic excision right-sided colon cancer surgery survival hemicolectomy = 0 surgical survival vs d3 + cme 0 colon cancer Leer másBackground Poor pulmonary function and chronic obstructive pulmonary disease (COPD) are associated with poorer overall survival (OS) in non-small-cell lung cancer (NSCLC) patients. Few studies have in...
diffusion capacity (dlco) prognosis small-cell lung cancer (sclc) lung first-line cycles pulmonary 95% sclc survival capacity chemotherapy cancer ed-sclc dlco < 60% os patients Leer másBackground Endoscopic resection for early oesophageal cancer was introduced around 2000 in the Netherlands. The scientific question was how the treatment and survival of early oesophageal and gastro-o...
esophageal neoplasms esophageal squamous cell carcinoma... esophageal adenocarcinoma surgery endoscopy survival rate therapy patients t1 cancer endoscopic oesophageal netherlands surgery treatment Leer másPURPOSE: This study aimed to gain a deeper understanding of the coping processes of breast cancer survivors (BCSs) during medical and occupational rehabilitation after acute treatment. METHODS: This s...
medical factors contextual coping cancer breast bcss study rehabilitation Leer másIntroduction Inflammation plays a significant role in various cancers, including lung cancer, where the inflammatory cytokine IL-1β is often elevated in the tumor microenvironment. Patients with lung ...
kyn cancer trp epithelial immortalized determine lung levels il-1β tdo2 adenocarcinoma Leer másBACKGROUND: Immune checkpoint inhibitors (ICIs) and their combination with other therapies such as chemotherapy, fail in most cancer patients. We previously identified the PDZ-LIM domain-containing pr...
drugs human chemotherapeutic pdlim2 lung cancer tumor Leer másBackground The gene cell division cycle associated 5 (CDCA5), also called sororin, has oncogenic characteristics and is upregulated in various carcinomas. Nevertheless, the involvement of CDCA5 in ova...
cdca5 tgf-β1 ovarian cancer proliferation metastasis migration cancer pathway cdca5 Leer másPurpose: To examine the safety and effectiveness of the combination of Camrelizumab and Abraxane + lobaplatin in advanced gastric cancer therapy. Methods: The data of 60 patients with advanced gastric...
regimen levels 05 p<0 lobaplatin abraxane + gastric cancer camrelizumab advanced study control Leer másSeveral studies have shown significant involvement of tumor-associated macrophages (TAMs) in the tumor microenvironment and cancer progression. However, no data on reliable TAM-related biomarkers are ...
tumor-associated macrophage prognostic signature immunotherapy tumor microenvironment colorectal cancer cancer data tam-related tams genes Leer másBackground Patients with advanced prostate cancer have a poor prognosis, and well-tolerated new treatment strategies are required to improve survival outcomes. Apalutamide is a novel androgen signalli...
apalutamide metastatic hormone-sensitive prost... non-metastatic castration-resistan... prostate cancer metastatic disease advanced mhspc prostate cancer treatment clinical adt Leer másBackground Colorectal cancer (CRC) is a common malignant tumor, and its occurrence and development are closely related to dysbiosis of gut microbes. Previously, we found calorie restriction altered th...
caloric restriction colorectal cancer intestinal metabolites gut microbiota mouse analysis crc d-proline isoleucyl-valine colorectal cancer model microbiota intestinal metabolites Leer másBACKGROUND: A breath test for volatile organic compounds has identified biomarkers associated with breast cancer. We evaluated the potential clinical and economic benefits of a breath test to detect w...
clinical population identified sensitivity asymptomatic costs reduce screening test specificity risk values breast cancer npv ppv negative low breath Leer másBreast cancer is a relatively common cancer among gynecological cancers. Its diagnosis often relies on the pathology of cells in the lesion. The pathological diagnosis of breast cancer not only requ...
utilizing computer science convolutional breast pathological cancer images Leer másBACKGROUND: The optimal duration of anticoagulation in patients with active cancer and venous thromboembolism (VTE) is unknown. Current clinical guidelines advocate anticoagulant therapy for 3–6 month...
thrombosis cancer-associated recurrence review active events venous thromboembolism studies rate cancer therapy anticoagulant discontinuation ci 95% patients Leer másBACKGROUND: LGBTQI (lesbian, gay, bisexual, transgender, queer and/or intersex) communities are increasingly recognized as a vulnerable and high-risk population in oncology. LGBTQI cancer carers, incl...
psychosocial distress cancer carers support Leer másBackground The main cause of voice hoarseness is vocal cord palsy (VCP) that may be induced by many diseases that could be due to local laryngeal or extra laryngeal causes, including neoplastic and no...
vocal cord palsy fdg pet ct hoarseness of voice suspected value 6% positive scans predictive results laryngeal neoplastic vs cancer vocal negative fdg ct extra vcp patients scan pet Leer másObjective There are studies on the nutritional status of type 2 diabetes (T2D), but there are no large cohort studies on the prognosis of Controlling Nutritional Status (CONUT) score for T2D. The aim ...
national health and nutrition exam... controlling nutritional status sco... cancer mortality all-cause mortality nutritional deaths association t2d status risk score mortality cancer Leer másObjective This study aimed to investigate the efficacy of inflammatory markers (NLR, PLR) combined with tumor markers (CA50, CA199, CEA) in the diagnosis of colorectal cancer metastasis by a single-ce...
colorectal cancer metastases biological indicators diagnosis diagnostic 0 study cea using ca199 ca50 regression diagnosis 05 logistic colorectal cancer patients nlr combined plr multiple Leer másThe epithelial–mesenchymal transition (EMT) is a critical tumor invasion and metastasis process. EMT enables tumor cells to migrate, detach from their original location, enter the circulation, circula...
emt tumor metastasis tumor microenvironments stromal cells secretions stromal cancer emt Leer másBackground Uterine cancer remains a serious medical problem worldwide. This study aimed to explore the global time trends of uterine cancer burden using the age-period-cohort model and forecast incide...
uterine cancer global burden of disease incidence death age-period-cohort model forecasting age-period-cohort burden 2019 global uterine cancer incidence Leer másBackground In industries worldwide, crystalline silica is pervasive and poses risks of pneumoconiosis and respiratory malignancies, with the latter being a knowledge gap in disease burden research tha...
disease burden silica mortality disability-adjusted life year (dal... average annual percentage change (... deaths global rate females males dalys pneumoconiosis burden 2019 cancer disease asmr 1990 asdr silica tbl -1 Leer másBACKGROUND: Glycosylation involved in various biological function, aberrant glycosylation plays an important role in cancer development and progression. Glycosyltransferase 8 domain containing 1 (GLT8...
cancer correlated prognosis expression function glycosyltransferase analyses potential gc Leer másBACKGROUND: Acute tumour embolism to the popliteal artery resulting in limb-threatening ischemia is a rare complication of neoplastic disease. Generally, tumors embolize to the pulmonary circulation v...
limb resulting lung cancer embolization left Leer másBackground Knowledge about thrombocytopenia among patients with solid tumors is scarce. We examined the risk of thrombocytopenia among patients with solid tumors and its association with adverse outco...
adverse cancer patients solid tumors thrombocytopenia Leer másDeep neural networks have demonstrated exceptional efficacy in stroke lesion segmentation. However, the delineation of small lesions, critical for stroke diagnosis, remains a challenge. In this stud...
labeling dbl 0 lesion Leer másThe emerging machine learning paradigm of decentralized federated learning (DFL) has the promise of greatly boosting the deployment of artificial intelligence (AI) by directly learning across distri...
communication dfl network learning Leer másLearning from human preference is a paradigm used in large-scale language model (LLM) fine-tuning step to better align pretrained LLM to human preference for downstream task. In the past it uses rei...
human preference dpo Leer másIn recent literature, matrix product (MP) codes and their duals have gained significant attention due to their application in the construction of quantum stabilizer codes. In this paper, we begin wi...
dual-containment previous code hermitian duality self-orthogonality galois codes Leer másPerson Re-Identification (ReID) aims to retrieve relevant individuals in non-overlapping camera images and has a wide range of applications in the field of public safety. In recent years, with the d...
learning method local personvit vision features self-supervised Leer másPolicy optimization methods benefit from a simple and tractable policy parametrization, usually the Gaussian for continuous action spaces. In this paper, we consider a broader policy family that rem...
policies heavy-tailed family policy Leer másIn this paper, we consider deploying multiple Unmanned Aerial Vehicles (UAVs) to enhance the computation service of Mobile Edge Computing (MEC) through collaborative computation among UAVs. In parti...
tasks computation computing service Leer másWith the increasing use of nonlinear devices in both generation and consumption of power, it is essential that we develop accurate and quick control for active filters to suppress harmonics. Time de...
network accurate control harmonic Leer másBy the blessing of our existing data communication system, we can communicate or share our information with each other in every nook and corner of the world within some few seconds but there are som...
traditional system communication data quantum Leer másFederated learning enables multiple clients to collaboratively train machine learning models under the overall planning of the server while adhering to privacy requirements. However, the server cann...
backdoor attacks Leer másDiffusion models excel at capturing the natural design spaces of images, molecules, DNA, RNA, and protein sequences. However, rather than merely generating designs that are natural, we often aim to ...
fine-tuning method generation guidance //github models Leer másExisting Latin treebanks draw from Latin's long written tradition, spanning 17 centuries and a variety of cultures. Recent efforts have begun to harmonize these treebanks' annotations to better trai...
treebanks Leer másHyperbolic embeddings have demonstrated their effectiveness in capturing measures of uncertainty and hierarchical relationships across various deep-learning tasks, including image segmentation and a...
training uncertainty euclidean learning models Leer másDue to domain shift, deep learning image classifiers perform poorly when applied to a domain different from the training one. For instance, a classifier trained on chest X-ray (CXR) images from one ...
image science computer learning Leer másLarge Language Models (LLMs) have excelled at language understanding and generating human-level text. However, even with supervised training and human alignment, these LLMs are susceptible to advers...
human language metrics evaluation Leer másLarge Language Models (LLMs) excel in stand-alone code tasks like HumanEval and MBPP, but struggle with handling entire code repositories. This challenge has prompted research on enhancing LLM-codeb...
tasks code Leer másBayesian estimation is a vital tool in robotics as it allows systems to update the robot state belief using incomplete information from noisy sensors. To render the state estimation problem tractabl...
estimation fourier motion systems filter robotics distributions Leer másVideo grounding is a fundamental problem in multimodal content understanding, aiming to localize specific natural language queries in an untrimmed video. However, current video grounding datasets me...
paragraph computer video multi-paragraph multimodal grounding Leer másThis paper proposes a framework for a privacy-safe iris presentation attack detection (PAD) method, designed solely with synthetically-generated, identity-leakage-free iris images. Once trained, the...
model contact privacy-safe iris images Leer másSupply Chain Finance is very important for supply chain competition, which is an important tool to activate the capital flow in the supply chain. Supply Chain Finance-related research can support mu...
blockchain-based data finance Leer másWearable systems provide continuous health monitoring and can lead to early detection of potential health issues. However, the lifecycle of wearable systems faces several challenges. First, effectiv...
systems updating epileptic auc wearable Leer másSecuring endpoints is challenging due to the evolving nature of threats and attacks. With endpoint logging systems becoming mature, provenance-graph representations enable the creation of sophistica...
dataset Leer másEnd-to-end interpretation is currently the prevailing paradigm for remote sensing fine-grained ship classification (RS-FGSC) task. However, its inference process is uninterpretable, leading to criti...
interpretable language process fine-grained ship fgsc Leer másThis chapter presents, from our research on inclusive software within the context of a diversity and inclusion based STEM program at the University of Victoria, INSPIRE: STEM for Social Impact (here...
software chapter development teams inclusive Leer másOne-shot Imitation Learning~(OSIL) aims to imbue AI agents with the ability to learn a new task from a single demonstration. To supervise the learning, OSIL typically requires a prohibitively large ...
semi-supervised task trajectories osil dataset learning Leer másThe global pandemic due to emergence of COVID 19 has created the unrivaled public health crisis. It has huge morbidity rate never comprehended in the recent decades. Researchers have made many effor...
covid 19 potential inhibitors Leer másPediatric Long COVID has been associated with a wide variety of symptoms, conditions, and organ systems, but distinct clinical presentations, or subphenotypes, are still being elucidated. In this expl...
conditions pediatric covid Leer másBackground Since the declaration of COVID-19 as a pandemic in 2020, its main symptoms have primarily affected the respiratory system. However, it also presents other systemic manifestations, including...
covid delta & omicron variant laryngopharyngeal manifestations patients study primarily paralysis fold exhibited laryngo pharyngeal covid-19 vocal related affection Leer másPediatric Long COVID has been associated with a wide variety of symptoms, conditions, and organ systems, but distinct clinical presentations, or subphenotypes, are still being elucidated. In this expl...
conditions pediatric covid Leer másPediatric Long COVID has been associated with a wide variety of symptoms, conditions, and organ systems, but distinct clinical presentations, or subphenotypes, are still being elucidated. In this expl...
conditions pediatric covid Leer másLong COVID continues to challenge public health by affecting a significant segment of individuals who have recovered from acute SARS-CoV-2 infection yet endure prolonged and often debilitating sympt...
research health review covid Leer másThe global pandemic due to emergence of COVID 19 has created the unrivaled public health crisis. It has huge morbidity rate never comprehended in the recent decades. Researchers have made many effor...
covid 19 potential inhibitors Leer másBackground Since the declaration of COVID-19 as a pandemic in 2020, its main symptoms have primarily affected the respiratory system. However, it also presents other systemic manifestations, including...
covid delta & omicron variant laryngopharyngeal manifestations patients study primarily paralysis fold exhibited laryngo pharyngeal covid-19 vocal related affection Leer másBACKGROUND: It is unknown if early COVID-19 monoclonal antibody (mAb) therapy can reduce risk of Long COVID. The mAbs amubarvimab/romlusevimab were previously demonstrated to reduce risk of hospitaliz...
36 reduce week covid covid-19 outcome placebo amubarvimab/romlusevimab Leer másLong COVID continues to challenge public health by affecting a significant segment of individuals who have recovered from acute SARS-CoV-2 infection yet endure prolonged and often debilitating sympt...
research health review covid Leer másLong COVID continues to challenge public health by affecting a significant segment of individuals who have recovered from acute SARS-CoV-2 infection yet endure prolonged and often debilitating sympt...
research health review covid Leer másWe leverage a recently published dataset of Amazon purchase histories, crowdsourced from thousands of US consumers, to study how online purchasing behaviors have changed over time, how changes vary ...
crowdsourced retail covid metrics grocery behaviors consumer-level amazon data purchases changes online Leer másAs a novel virus, COVID introduced considerable uncertainty into the daily lives of people all over the globe since late 2019. Relying on twenty-three semi-structured interviews with parents whose c...
covid Leer másThe global pandemic due to emergence of COVID 19 has created the unrivaled public health crisis. It has huge morbidity rate never comprehended in the recent decades. Researchers have made many effor...
covid 19 potential inhibitors Leer másWe leverage a recently published dataset of Amazon purchase histories, crowdsourced from thousands of US consumers, to study how online purchasing behaviors have changed over time, how changes vary ...
crowdsourced retail covid metrics grocery behaviors consumer-level amazon data purchases changes online Leer másIMPORTANCE: Updated knowledge regarding the global prevalence of long COVID (or post-COVID-19 condition), its subtypes, risk factors, and variations across different follow-up durations and geographic...
diagnosis confirmed meta-analysis systematic healthcare primary objective regions estimated ci 95% positive covid-19 review symptoms meta-analyzed data covid prevalence population subtypes studies study global risk follow-up Leer másLong COVID continues to challenge public health by affecting a significant segment of individuals who have recovered from acute SARS-CoV-2 infection yet endure prolonged and often debilitating sympt...
research health review covid Leer másBackground Since the declaration of COVID-19 as a pandemic in 2020, its main symptoms have primarily affected the respiratory system. However, it also presents other systemic manifestations, including...
covid delta & omicron variant laryngopharyngeal manifestations patients study primarily paralysis fold exhibited laryngo pharyngeal covid-19 vocal related affection Leer másPediatric Long COVID has been associated with a wide variety of symptoms, conditions, and organ systems, but distinct clinical presentations, or subphenotypes, are still being elucidated. In this expl...
conditions pediatric covid Leer másLong COVID continues to challenge public health by affecting a significant segment of individuals who have recovered from acute SARS-CoV-2 infection yet endure prolonged and often debilitating sympt...
research health review covid Leer másIMPORTANCE: Updated knowledge regarding the global prevalence of long COVID (or post-COVID-19 condition), its subtypes, risk factors, and variations across different follow-up durations and geographic...
diagnosis confirmed meta-analysis systematic healthcare primary objective regions estimated ci 95% positive covid-19 review symptoms meta-analyzed data covid prevalence population subtypes studies study global risk follow-up Leer másWe leverage a recently published dataset of Amazon purchase histories, crowdsourced from thousands of US consumers, to study how online purchasing behaviors have changed over time, how changes vary ...
crowdsourced retail covid metrics grocery behaviors consumer-level amazon data purchases changes online Leer másWe leverage a recently published dataset of Amazon purchase histories, crowdsourced from thousands of US consumers, to study how online purchasing behaviors have changed over time, how changes vary ...
crowdsourced retail covid metrics grocery behaviors consumer-level amazon data purchases changes online Leer másBackground Since the declaration of COVID-19 as a pandemic in 2020, its main symptoms have primarily affected the respiratory system. However, it also presents other systemic manifestations, including...
covid delta & omicron variant laryngopharyngeal manifestations patients study primarily paralysis fold exhibited laryngo pharyngeal covid-19 vocal related affection Leer másAim Long-haul COVID-19 poses a profound burden to public health. According to the CDC, approximately one in five people who contract COVID-19 have lingering COVID-related symptoms 3 months after testi...
long covid disease severity veterans’ health covid-19 epidemiology covid positive veterans symptom risk acute developing covid-19 Leer másBackground Predicting the short-term prognosis and severity of tuberculosis meningitis (TBM) patients without HIV infection can be challenging, and there have been no prior studies examining the neutr...
tuberculosis meningitis neutrophil-lymphocyte ratio (nlr) prognosis severity ci stage predicting meningitis using tuberculosis severity 95% p = 0 0 nlr short-term tbm hiv infection prognosis Leer másPurpose of Review An HIV cure that eliminates the viral reservoir or provides viral control without antiretroviral therapy (ART) is an urgent need in children as they face unique challenges, including...
hiv cure pediatric nonhuman primate reservoir nhp hiv cure Leer másHIV biomedical research groups have prioritized community support and representation as exemplified by the creation of Community Advisory Boards (CABs). Most CABs bring diverse stakeholders to advise ...
community engagement patient and public involvement community advisory board community-based organizations advocacy hiv cure research lessons learned learned lessons support advisory based mdc paper beat-hiv research engagement cure ceg efforts collaboratory cbo cab hiv community model Leer másBackground Despite the highest (88%) Prevention of Mother-To-Child Transmission (PMTCT) of HIV coverage in Eastern Africa, 50% of new HIV infections in children aged 0–14 years occur in the region. Ob...
hiv-exposed infants feeding modality hiv-transmission risk factors ethiopia predictors exclusively facilities modalities 95%ci infants risk months hiv Leer másBackground Women’s empowerment is an important factor for HIV prevention, but the association with HIV-related indicators has never been quantified. In this study, we examined the association between ...
women’s empowerment hiv testing demographic and health surveys sub-saharan africa, sexual health,... 95% highly hiv empowered or = 1 women hiv-related indicators women’s Leer másThis study evaluated the association between HIV risk perception and sociodemographic and behavioral characteristics among cisgender female sex workers in the five regions of Brazil. A cross-sectional...
risk perception health risk human immunodeficiency virus sex workers epidemiology study female sexual behavioral sociodemographic factors risk hiv sex perception workers participants Leer másBACKGROUND: The global campaign for “Undetectable equals Untransmittable” (U = U) seeks to spread awareness of HIV treatment as prevention, aiming to enhance psychological well-being and diminish stig...
south develop hiv intervention u = u Leer másBackground Despite the success of antiretroviral therapy (ART), people living with HIV (PLWH) suffer from a high burden of pulmonary diseases, even after accounting for their smoking status. Cytotoxic...
hiv smoking people living with hiv (plwh) pulmonary immunity cd8 t-cells lung trm tissue resident cytotoxic non-smokers expression infection cd103 cd8 hiv Leer másSubstance use disorders (SUD) and drug addiction are major threats to public health, impacting not only the millions of individuals struggling with SUD, but also surrounding families and communities. ...
risk addiction brain effects single-cell hiv Leer másThe prevalence of HBV, HCV, and TB was high among Iranian PLWH The prevalence was higher among at-risk groups such as PWIDs and homeless people The prevalence of HCV was more than HBV and TB among PLW...
hiv hepatitis b hepatitis c tuberculosis systematic review iran people study studies plwh ci 95% tb 0 Leer másBackground Diagnosing a life-threatening disease like the human immunodeficiency virus (HIV) can be unbearable to the individual, which has implications for their subsequent care-seeking decision-maki...
hiv diagnosis interpretation psychological ghana diagnosis services health mental reactions linkage study positive improve targets care participants hiv Leer másBackground Chronic inflammation has been described in people living with HIV (PLHIV) receiving antiretroviral therapy (ART) despite viral suppression. Inflammation associated non-communicable diseases...
atherosclerosis dyslipidemia hiv infection inflammatory biomarker pitavastatin hiv p=0 levels study treatment baseline vs placebo receiving pitavastatin cells Leer másBACKGROUND: Coverage of HIV testing remains sub-optimal in West Africa. Between 2019 and 2022, the ATLAS program distributed ~400 000 oral HIV self-tests (HIVST) in Côte d’Ivoire, Mali, and Senegal, p...
reach associated users factors hivst 0 aor vs [0 education first-time distribution testers secondary hiv testing Leer másIn Kenya similar to other countries in Eastern and Southern Africa There is a disproportionately high burden of the global HIV incidence among youth ages 15–24 years, and where adolescent girls and yo...
hiv adolescents sexual-debut transactional sex multiple sexual partners burden kenya hiv sex sexual Leer másBackground It is evident that public health education interventions to promote the use of condoms against HIV infections in Ghana have yielded modest results. However, existing studies in the field of...
risk preference risk-averse risk-lover condom use hiv/aids ghana education hiv/aids public condom predicted abstain sex individual preference behaviour health hiv individuals preferences condoms Leer másIntroduction Talaromycosis is a common invasive fungal disease in patients with HIV. However, its association with bone destruction is unusual in AIDS patients with talaromycosis. Case Presentation Th...
hiv case report ngs infection destruction Leer másBACKGROUND: In 2020, 14% of diagnosed persons living with HIV (PLWH) in Kenya were not taking antiretroviral therapy (ART), and 19% of those on ART had unsuppressed viral loads. Long-acting antiretrov...
art interviews hiv plwh potential patients ki la-art injections kenya antiretroviral delivery Leer másINTRODUCTION: Linkage to HIV care remains suboptimal among men. We investigated the effectiveness of a male-targeted HIV-specific decision support app, Empowering People through Informed Choices for H...
support eligible trial intervention received app hiv epic-hiv communities 13 Leer másBACKGROUND: The aim of this study is to examine cervical cancer screening (CCS) uptake among women living with hypertension and HIV in Tanzania. METHODS: We used the recently released 2022 Tanzania De...
chronic tanzania study positive hypertension hiv women screening Leer másBackground High blood pressure (HBP), including hypertension (HTN), is a predictor of cardiovascular events, and is an emerging challenge in young persons. The risk of cardiovascular events may be fur...
young adult adolescent hiv hypertension prehypertension uganda cardiovascular persons aged 25 years bp 13 hbp 95% ci age prevalence associated stage Leer másBackground Managing multidrug-resistant (MDR) HIV infections in children is particularly challenging due to the lack of experience with new drugs in the pediatric setting. Second-line albuvirtide (ABT...
hiv-child aids albuvirtide drug resistance case report regimen abt-based therapy children hiv Leer másDrug use, mental distress, and other psychosocial factors threaten HIV care for youth living with HIV (YLWH). We aimed to identify syndemic psychosocial patterns among YLWH and examine how such patter...
syndemic youth living with hiv hiv care continuum psychosocial conditions latent outcomes classes relative 4% polydrug-socioeconomic ylwh psychosocial distress-socioeconomic syndemic-free syndemic hiv class Leer másBackground Fatal drug overdoses and serious injection-related infections are rising in the US. Multiple concurrent infections in people who inject drugs (PWID) exacerbate poor health outcomes, but lit...
people who inject drugs injection drug use opioid use disorder hiv hepatitis c bacterial infections endocarditis serious injection related infectio... drug overdose syndemic idu validated injection-related clinical 000 results incidence hospitalization multimorbidity associated model infections overdose drug outcomes targets sets serious pwid fatal Leer másBackground Antiretroviral therapy enables people living with HIV to live long lives, and these advances have transformed HIV infection from an acute to a chronic disease. Many non-communicable disease...
chronic comorbidity incidence rate people living with hiv physical activity ethiopia = 0 adult comorbidities low ethiopia [ahr comorbidity living people hiv survival chronic study activity physical ci 95% Leer másBackground HIV/AIDS is a global health challenge and continues to threaten lives in sub-Saharan African countries such as Ghana. One of the important interventions for controlling its transmission is ...
hiv hiv testing hiv prevention young women ghana health aor = 1 education 95% ci testing hiv aor = 2 [1 ghana Leer másBackground The elderly bear the highest burden of South Africa’s estimated annual > 10 million influenza cases and > 11,000 influenza-related deaths. Unvaccinated healthcare workers (HCWs) are at high...
influenza healthcare workers elderly vaccine vaccination south africa healthcare care health study uptake vaccine influenza south elderly participants hcws Leer másBackground Vaccination is essential to protect from influenza and recently from COVID-19, yet uptake in Lebanon is suboptimal. Several factors determine uptake including knowledge, attitude and polici...
influenza covid-19 vaccine hesitancy concept lebanon review scoping investigated vaccine intent covid-19 studies determinants influenza lebanon Leer másBACKGROUND: Corticosteroid treatment has been widely used in the treatment of septic shock, influenza, and ARDS, although some previous studies discourage its use in severe influenza patients. This mu...
significantly influenza odds increased impact mortality hospital associated ards treatment Leer másBACKGROUND: Influenza vaccination is uncommon in low-resource settings. We evaluated aspects of operational feasibility of influenza vaccination programs targeting risk groups in the World Health Orga...
risk targeting capacity 0% vaccination country influenza pregnant <5 ≥65 women storage persons Leer másBACKGROUND: There is good evidence of vaccine effectiveness in healthy individuals but less robust evidence for vaccine effectiveness in the populations targeted for influenza vaccination. The live at...
associated 2015/16 events 2010/11 recommended six adverse significant seasons influenza ci 95% study vaccine vaccination laiv tiv scottish people Leer másBackground Currently, the influenza epidemic in China is at a high level and mixed with other respiratory diseases. Current studies focus on regional influenza and the impact of environmental pollutan...
influenza spatio-temporal evolution pattern pollutants generalized additive model space-time cube model correlated spatial evolution incidence epidemic nonlinear correlation environmental china Leer másBackground The transmission dynamics of influenza virus within healthcare settings are not fully understood. Capturing the interplay between host, viral and environmental factors is difficult using co...
healthcare-associated infections influenza infection prevention and control system dynamics decision support systems modelling season dynamics prophylaxis antiviral simulations system dynamic influenza transmission model patients Leer másInfluenza viruses not only cause respiratory illness, but also have been reported to elicit neurological manifestations following acute viral infection. The central nervous system (CNS) has a specific...
blood–brain barrier influenza a virus (iav) hbmecs cns neurodegenerative diseases rnaseq brain endothelial response hbmecs genes influenza cells Leer másLet us study viruses and the role of sialic acids in their first step of reproduction, the attachment to cells. We begin our study with the help of the "Earth's virology course", created by Vincent R...
influenza attachment sars-cov-2 acid cells study sialic Leer másInfluenza A virus activates cellular inflammasome pathways, though it remains unknown whether many of the effector proteins downstream of inflammasome activation promote virus clearance or instead pro...
infection decreased inflammasome neutrophil ko lung virus gsdmd mice influenza Leer másBackground Acute respiratory distress syndrome (ARDS) is responsible for 400,000 deaths annually worldwide. Few improvements have been made despite five decades of research, partially because ARDS is ...
acute respiratory distress syndrom... mycobiota microbiota cap-related aetiologies patients = 0 mycobiota ards microbiota covid-19 lower bacterial influenza Leer másInteractions between COVID-19 and other pathogens may change their dynamics. Specifically, this may hinder the modelling of empirical data when the symptoms of both infections are hard to distinguis...
covid-19 influenza Leer másBACKGROUND: Observational studies of influenza vaccination are criticized as flawed due to unmeasured confounding. The goal of this cohort study was to explore the value and role of secondary claims d...
patients study hr hospitalizations models health season influenza Leer másThe covid-19 pandemic that occurred in the beginning of 2020 has affected all sectors, particularly in health and economic sectors. The Avian Influenza Virus (AIV), a zoonotic virus that have been rep...
avian influenza virus reassortment zoonoses study health covid-19 java aivs swabs subtype h3 virus samples tested poultry positive indonesia influenza Leer másBACKGROUND: Antibody responses to non–egg-based standard-dose cell-culture influenza vaccine (containing 15 µg hemagglutinin [HA]/component) and recombinant vaccine (containing 45 µg HA/component) dur...
iiv/iiv randomized titers ratios y2 gmt cciiv/riv quadrivalent compared influenza immunogenicity consecutive hcp vaccine Leer másAcute respiratory infections (ARIs) are caused by many pathogens and among them, respiratory viruses hold a very privileged place. Epidemiological studies have highlighted numerous case...
drugs données antivirals infectés au nos ngs major base exploitation infected d’infections virus respiratory repositionnement human influenza médicaments therapeutic vitro viruses repositioning respiratoires diltiazem infections Leer másBackground Immune dysregulation is a feature of sepsis. However, a comprehensive analysis of the immune landscapes in septic patients has not been conducted. Objectives This study aims to explore the ...
septic shock acute respiratory distress syndrom... influenza receiver operating characteristic ... intensive care unit (icu) package abundance differential immune ratio eosinophil/b memory using analysis sepsis cell survival Leer másInfluenza viruses mutate rapidly and can pose a threat to public health, especially to those in vulnerable groups. Throughout history, influenza A viruses have caused pandemics between different spe...
algorithms influenza sequences Leer másInternational audience; Introduction: Influenza vaccination coverage currently remains below the 75% recommended threshold by the World Health Organization. To correct this situation, ex...
[sdv vaccinations survey community training regarding pharmacy sciences expectations vaccination mesh health pharmacies influenza Leer másInfluenza (flu) infection is a leading cause of respiratory diseases and death worldwide. Although seasonal flu vaccines are effective at reducing morbidity and mortality, such effects rely on the odd...
vaccination functional responses viruses selection positive flu np ctl influenza Leer másThe generation time, representing the interval between infections in primary and secondary cases, is essential for understanding and predicting the transmission dynamics of seasonal influenza, includi...
incubation influenza time period transmission data Leer másChina has a huge population with respiratory diseases, these diseases should be managed well in primary care, however, primary care physicians’ knowledge level of these diseases were unknown. The aim ...
physicians’ 7% 1% china diseases respiratory physicians 0% cap care primary knowledge asthma influenza Leer másInfluenza poses a significant threat to public health, particularly among the elderly, young children, and people with underlying dis-eases. The manifestation of severe conditions, such as pneumonia...
host viruses computer science protein data influenza sequences Leer másMacrophages have a vital role in phagocytosis and antiviral effect against invading influenza viruses. Previously, we found that methionine enkephalin (MENK) inhibited influenza virus infection by upr...
macrophage menk proteomics analysis polarization phagosome influenza deps proteins proteomics virus macrophages menk Leer másBACKGROUND: The European Medicines Agency (EMA) requires enhanced safety surveillance to be conducted for annual seasonal influenza vaccines with the aim of rapidly detecting any potential new safety ...
2020/21 finland season adr significant clinically enhanced influenza reported adrs rate vaccine suspected reporting safety Leer másEmerging fungal pathogens are a global challenge for humankind. Many efforts have been made to understand the mechanisms underlying pathogenicity in bacteria, and OMICs techniques are largely responsi...
emerging pathogens genome evolution extremophiles rna-seq antifungals fungal fungi resistance pathogens genomes scedosporium Leer másBackground The production of succinic acid (SA) from biomass has attracted worldwide interest. Saccharomyces cerevisiae is preferred for SA production due to its strong tolerance to low pH conditions,...
succinic acid genetic background comparative transcriptomic analysi... response mechanism acid production folding study tolerance whereas cerevisiae strains sa genes protein significantly Leer másBackground The gut microbiota plays a crucial role in regulating the host’s immune responses during aging, which was characterized by a different abundance of bacteria in several age groups. Main body...
gut microbiota aging inflammatory disease metabolism probiotic gut microbiota Leer másObjectives Methicillin-resistant Staphylococcus aureus (MRSA) is a challenging global health threat, resulting in significant morbidity and mortality worldwide. This study aims to determine the molecu...
methicillin-resistant (mrsa) st5-scc ii-t311 bloodstream infections (bsis) antimicrobial susceptibility virulence genes typing non-st5-ii-t311 aureus mec china east st5-ii-t311 mrsa clone Leer másBackground The in-depth understanding of the role of lateral genetic transfer (LGT) in phage-prophage interactions is essential to rationalizing phage applications for human and animal therapy, as wel...
bacteriophage phage prophage genetic recombination lateral genetic transfer intergeneric recombination campylobacter phage staphylococcus listeria escherichia salmonella encoding interactions virulent genes industrial potential recombination genetic hosts Leer másBackground Bacteroides fragilis group (BFG) species are the most significant anaerobic pathogens and are also the most antibiotic-resistant anaerobic species. Therefore, surveying their antimicrobial ...
antibiotic resistance antibiotic resistance genes gut lumen gut mucosa intestinal microbiota gene study erm bfg microbiota genes bacteroides strains intestinal Leer másBackground The most serious challenges in medicinal ‘Sanghuang’ mushroom production are the fungal diseases caused by various molds. Application of biological agents has been regarded as a potential c...
‘sanghuang’ mushroom fungal diseases soil microbiome biocontrol agents fc soil hc trichoderma ‘sanghuang’ diseases cultivation samples fungal Leer másPurpose The textile industry’s previous chemical use resulted in thousands of practical particulate emissions, such as machine component damage and drainage system blockage, both of which have practic...
biopolishing cellulase industry microorganisms textile production industry processing textile fermentation Leer másIn the present study, three mitogenomes from the Bipolaris genus ( Bipolaris maydis , B. zeicola , and B. oryzae ) were assembled and compared with the other two reported Bipolaris mitogenomes ( B. or...
mitogenome intron gene rearrangement comparative analysis phylogenetic analysis core 13 study bipolaris pcgs gene five species Leer másFungal sinusitis are very often caused by Aspergillus spp. Dematiaceae spp. and mucomycoses. Sinusitis with Scedosporium spp is very rare, especially in immunocompetent humans. A 42-year-old female pr...
fungal rhino sinusitis mycology rhinology scedosporium apiospermum caused sinus spp rare scedosporium Leer másBackground Impaired respiratory and intestinal microbiome composition is linked to cystic fibrosis lung disease severity. In people with cystic fibrosis (pwCF), regular exercise is recommended to dela...
cystic fibrosis microbiome gut-lung axis physical exercise nutrition antibiotics intervention stool pwcf intestinal composition sputum microbiome exercise study Leer másBackground Endophytic Aspergillus species produce countless valuable bioactive secondary metabolites. In the current study, Aspergillus flavus an endophyte from the soft coral Sarcophyton ehrenbergi...
in silico profile antimicrobial anticancer endophyte dynamic simulation nmr spectroscopy mic endophytic flavus ml compounds antimicrobial activity Leer másVibrio cholerae , as a natural inhabitant of the marine environment is among the world-leading causes of diarrheal diseases. The present study aimed to investigate the genetic relatedness of Iran 2012...
pfge mlst cholera iran wgs pulsotypes isolates st579 presence recent causes strains st69 non-st69/non-st75 resistance 2016 st75 sts cholera outbreaks cholerae Leer másBackground Probiotics have recently been applied in aquaculture as eco-friendly alternatives to antibiotics to improve fish health, simultaneously with the increase of production parameters. The prese...
tilapia fish probiotics aquaculture activity functional isolates lab Leer másBackground As antibiotics and chemotherapeutics are no longer as efficient as they once were, multidrug resistant (MDR) pathogens and cancer are presently considered as two of the most dangerous threa...
biosynthesized selenium nanopartic... selenium/chitosan-nanoconjugate antimicrobial enzymes anticancer parvulus streptomyces mar4 cell nch biosynthesized anticancer cytotoxicity antimicrobial Leer másBackground The rising prevalence of extended-spectrum beta-lactamase and carbapenemase-producing Enterobacteriaceae (ESβL-PE) in street foods poses a significant risk to human health due to its epidem...
extended-spectrum β-lactamase street-vended food foods respectively food extended-spectrum spp street Leer másThe existence of a placental microbiota is debated. The human placenta has historically been considered sterile and microbial colonization was associated with adverse pregnancy outcomes. Yet, recent D...
16s rrna gene sequencing low microbial biomass sampling microbiome placenta sterile womb datasets signals contamination dna placental bacterial placentas microbiota Leer másBackground Migratory birds exhibit heterogeneity in foraging strategies during wintering to cope with environmental and migratory pressures, and gut bacteria respond to changes in host diet. However, ...
black-necked crane diet gut fungi wintering period wintering late winter black-necked period cranes significantly fungi diet composition food gut Leer másBackground Multi-drug-resistant organisms (MDROs) in gram-negative bacteria have caused a global epidemic, especially the bacterial resistance to carbapenem agents. Plasmid is the common vehicle for c...
plasmid typing incompatibility groups gram-negative bacteria carbapenem resistance incompatibility bacteria replicon antimicrobial mdros plasmid Leer másPurpose Biovalorization of lignin-derived aromatic monomers such as ferulic acid (FA) has attracted considerable interest. The cold-adapted strain Paraburkholderia aromaticivorans AR20-38 converts FA ...
lignin-derived aromatic monomers ferulic acid vanillin vanillic acid bioconversion cold-adapted ... culture 5 mm yields glucose production temperature conditions fa vanillin acid Leer másBackground Thermostable microorganisms are extremophiles. They have a special genetic background and metabolic pathway and can produce a variety of enzymes and other active substances with special fun...
thermo-tolerant microorganism ichip tengchong hot spring uncultured microorganisms ichip spring isolated isolate genera thermo-tolerant microorganisms bacteria strains Leer másPurpose The biodegradation of skatole was used as a starting point in this study, and existing strains of degrading NH_3 and H_2S in the laboratory were combined to create a composite deodorant. The d...
skatole human feces composite deodorant metabolic analysis microbial community odor rate effect indole agent nh_3 liquid h_2s human feces composite bacteria microbial Leer másBackground Although Basidiomycota produce pharmaceutically and ecologically relevant natural products, knowledge of how they coordinate their primary and secondary metabolism is virtually non-existent...
aromatic acetaldehyde synthase basidiomycota metabolic flux psilocybin tryptophan encoding psilocybe metabolism psilocybin synthase -tryptophan genes biosynthesis Leer másCSF-venous fistulas are an increasingly recognized type of CSF leak that can be particularly challenging to detect, even with recently improved imaging techniques. Currently, most institutions use dec...
imaging photon-counting myelography Leer másOvulation disorders are a serious problem for humans and livestock. In female rodents, kisspeptin neurons in the anteroventral periventricular nucleus (AVPV) are responsible for generating a luteinizi...
administration disorders via ovx hormone livestock induce humans increased level increase avpv ovulation kisspeptin neurons surge atp lh significantly proestrous estrogen hindbrain 5-triphosphate adenosine receptor Leer másBackground There are increasing reports of cases of Guillain-Barré syndrome (GBS), as an adverse event of an immune checkpoint inhibitor (ICI) but postmarket data on the incidence of this remains scar...
data event reports reporting study avelumab faers checkpoint associated adverse ror Leer másBACKGROUND AND PURPOSE: Surgical clipping and endovascular treatment are commonly used in patients with unruptured intracranial aneurysms. We compared the safety and efficacy of the 2 treatments in a ...
surgical failure surgery risk primary outcome relative 95% ci treatment patients clipping aneurysms intracranial unruptured endovascular Leer másAge-related decline in visual functions is a prevalent health problem among elderly people, and no effective therapies are available up-to-date. Axon degeneration and myelin loss in optic nerves (ONs)...
optic deficits age-dependent months degeneration ol generation function ons turnover visual mice oligodendrocyte age-related Leer másBACKGROUND AND PURPOSE: Infarct evolution after endovascular treatment varies widely among patients with stroke and may be affected by baseline characteristics and procedural outcomes. Moreover, IV al...
imaging occlusion evolution treatment endovascular baseline interquartile ctp ml range volume follow-up alteplase patients Leer másStroke-like migraine attacks after radiation therapy (SMART) syndrome is a delayed complication of cranial irradiation, with subacute onset of stroke-like symptoms including seizures, visual disturban...
features imaging clinical Leer másBACKGROUND AND PURPOSE: IV thrombolysis with alteplase before mechanical thrombectomy for emergent large-vessel-occlusion stroke is associated with access-site bleeding complications. However, the inc...
patients 2% thrombectomy mechanical stroke versus large-vessel-occlusion femoral complications access-site alteplase tenecteplase Leer másBACKGROUND AND OBJECTIVE: Retinal vascular density (VD) measured using optical coherence tomography with angiography (OCTA) has been suggested as a potential marker of intracerebral vascular changes i...
patients retinal vd Leer másHearing loss and deafness, as a worldwide disability disease, have been troubling human beings. However, the auditory organ of the inner ear is highly heterogeneous and has a very limited number of ce...
Leer másBACKGROUND: Potentially substantial impacts on the prognosis have been observed in individuals undergoing endovascular treatment due to cytochrome P450 2c19 (CYP2C19) polymorphism. In an attempt to im...
stenting artery events carotid adverse statistical cerebral difference polymorphism patients cyp2c19 endovascular prognosis Leer másBACKGROUND: The beneficial effects of gardening as a form of physical activity have garnered growing interest in recent years. Existing research suggests that physical activity enhances brain function...
literature function reviewers studies protocol review systematic physical activity search Leer másOBJECTIVE: As personality changes and personality disorders are frequently observed in multiple sclerosis (MS), personality may be a prognostic factor for this disease. The present study investigated ...
multiple facet personality p = 0 ms Leer másSleep loss pervasively affects the human brain at multiple levels. Age-related changes in several sleep characteristics indicate that reduced sleep quality is a frequent characteristic of aging. Conve...
night recovery brain deprivation total age loss Leer másBACKGROUND: The habenula is a major regulator of serotonergic neurons in the dorsal raphe, and thus of brain state. The functional connectivity between these regions is incompletely characterized. Her...
vhb displayed simple excitatory modeling response dorsal habenula neurons raphe Leer másAge-related decline in visual functions is a prevalent health problem among elderly people, and no effective therapies are available up-to-date. Axon degeneration and myelin loss in optic nerves (ONs)...
optic deficits age-dependent months degeneration ol generation function ons turnover visual mice oligodendrocyte age-related Leer másMany social animals can recognize other individuals by their vocalizations. This requires a memory system capable of mapping incoming acoustic signals to one of many known individuals. Using the zebra...
songs individual vocalizations male communication hvc recognition memory auditory memories ncm Leer másBACKGROUND: Functional movement disorders (FMDs) and functional seizure (FS) are the two most important subcategories of functional neurologic disorders (FNDs). OBJECTIVES: This study aimed to discern...
fmd common disorders study patients functional 0 fs Leer másOver the years, several interventions have been implemented, including Lego® Therapy, with the aim of supporting and implementing social and communication skills impairments in Autism Spectrum Disorde...
child Leer másBACKGROUND: Migraine is the second most common prevalent disorder worldwide and is a top cause of disability with a substantial economic burden. Many preventive migraine medications have notable side ...
aes medications bta incidence migraine drugs disorders Leer másMultiple sclerosis (MS) is regarded as a chronic inflammatory disease that leads to demyelination and eventually to neurodegeneration. Activation of innate immune cells and other inflammatory cells in...
glial cells Leer másBACKGROUND: The glycinergic system plays an important inhibitory role in the mouse central nervous system, where glycine controls the excitability of spinal itch- and pain-mediating neurons. Impairmen...
alpha brainstem analysis glra3 glycine expression Leer másThe incidence rate of anxiety and depression is significantly higher in patients with inflammatory bowel diseases (IBD) than in the general population. The mechanisms underlying dextran sulfate sodium...
induced lcn2 Leer másBACKGROUND AND PURPOSE: Mechanical thrombectomy appears to be a promising option for distal medium-vessel occlusions, for which intravenous thrombolysis is effective but may be insufficient when used ...
collapse distal clots arterial versus first-pass recanalization aspiration Leer másINTRODUCTION: Isolated infarction of the fornix is a relatively rare stroke syndrome frequently associated with amnesia. The long-term cognitive outcome in cases of acute fornix infarction is poorly u...
neuropsychological acute cognitive infarction amnesia Leer másParkinson's disease (PD) is a multifactorial neurodegenerative disease characterized by the degeneration of dopaminergic neurons from the substantia nigra pars compacta (SNc) leading to...
supplementation supplémentation nutritional l’intégrité maintien results involvement system système maintenance integrity révèlent nutritionnelle vitamine adulte striatum vitamin l’âge pathway signaling rétinoïdes retinoid dopaminergic disease d’une nigro-striatal signalisation mp adulthood pd parkinson nigro-striée voie Leer másPeople with Parkinson's disease must be regularly monitored by their physician to observe how the disease is progressing and potentially adjust treatment plans to mitigate the symptoms. Monitoring t...
science techniques parkinson methods disease voice using Leer másSex differences in Parkinson Disease (PD) risk are well-known. However, it is still unclear the role of sex chromosomes in the development and progression of PD. We performed the first X-chromosome Wi...
latin american cohorts parkinson cohort disease 0 pd Leer másParkinson's disease is a widespread neurodegenerative condition necessitating early diagnosis for effective intervention. This paper introduces an innovative method for diagnosing Parkinson's diseas...
learning signals model method diagnosis accuracy diagnostic machine parkinson disease Leer másParkinson's disease (PD) is a chronic, progressive neurodegenerative condition; characterized with the degeneration of the nigrostriatal dopaminergic pathway and neuroinflammation. During PD progressi...
parkinson receptor activity development disease pd p2y12r Leer másOBJECTIVES: To investigate potential risk factors for Parkinson’s disease (PD) in elderly individuals rural living in Turkey. METHODS: In total, 72 consecutive elderly Parkinson disease patients refer...
elderly turkey living iğdır parkinson disease patients water consumption Leer másPPINtonus is a system for the early detection of Parkinson's Disease (PD) utilizing deep-learning tonal analysis, providing a cost-effective and accessible alternative to traditional neurological ex...
network pd science detection parkinson ppintonus Leer másIn this contribution, we present the results of a case study on the impact of rhythmic priming, i.e. listening to rhythmic auditory stimuli, on speech production in Parkinson’s disease....
rhythm prosody aspects priming parkinson production rhythmic disease Leer másPeople with Parkinson's disease must be regularly monitored by their physician to observe how the disease is progressing and potentially adjust treatment plans to mitigate the symptoms. Monitoring t...
science techniques parkinson methods disease voice using Leer másInternational audience; L-Dopa induced dyskinesia (LID) is a debilitating side effect of dopamine replacement therapy for Parkinson's Disease. The mechanistic underpinnings of LID remain...
neurons parkinson smoothened lid l-dopa dopamine Leer másDecline of protein quality control in neurons contributes to age-related neurodegenerative disorders caused by misfolded proteins. 4E-BP1 is a key node in the regulation of protein synthesis, as activ...
control parkinson quality activation proteins primary protein 4e-bp1 stress misfolded 4e-bp1-overexpressing mitochondrial unfolded response neurons disease Leer másInternational audience; Background: Available treatments for Parkinson's disease (PD) are only partially or transiently effective. Identifying existing molecules that may present a thera...
learning machine causation reverse algorithm identifying disease drugs parkinson Leer másBACKGROUND: Inhibiting catechol‐O‐methyltransferase extends the plasma half‐life of levodopa, potentially allowing physicians to optimize the levodopa regimen in patients with Parkinson's disease (PD)...
patients 50 mg dose parkinson levodopa/carbidopa motor lower time levodopa Leer másMost patients with idiopathic REM sleep behavior disorder (iRBD) will develop an overt α-synucleinopathy over time, with a rate of phenoconversion of 73.5% after 12 years from diagnosis. Several marke...
rbd rem sleep behavior disorder neurodegeneration parkinson biomarkers idiopathic disorder behavior retrospective risk study Leer másInternational audience; Based on recent studies addressing some issues of exercise benefits in patients with Parkinson disease, we humbly invite to debate interdisciplinary challenges to...
parkinson disease Leer másNeovascular age-related macular degeneration (nAMD) remains a major cause of visual impairment, despite the continuous repeated intravitreal administration of anti-VEGF therapies that p...
pd namd maladie néovascularisation disease néovasculaire patients parkinson dmla Leer másBackground Parkinson's disease (PD) is a chronic progressive neurodegenerative disabling disease and involves about 1–3% of the worldwide population over the age of 60. A significant prevalence of psy...
parkinson's disease depressive symptoms non-motor symptoms mmse cas cognition parkinson females mean males age disease scale symptoms Leer másParkinson's disease (PD) is a multifactorial neurodegenerative disease characterized by the degeneration of dopaminergic neurons from the substantia nigra pars compacta (SNc) leading to...
supplementation supplémentation nutritional l’intégrité maintien results involvement system système maintenance integrity révèlent nutritionnelle vitamine adulte striatum vitamin l’âge pathway signaling rétinoïdes retinoid dopaminergic disease d’une nigro-striatal signalisation mp adulthood pd parkinson nigro-striée voie Leer másHeterochromatin disorganization is a key hallmark of aging and DNA methylation state is currently the main molecular predictor of chronological age. The most frequent neurodegenerative ...
parkinson damage disorganization dopaminergic dna methylation heterochromatin Leer másImpulsivity is a behavioral trait that is elevated in many neuropsychiatric disorders. Parkinson's disease (PD) patients can exhibit a specific pattern of reward-seeking impulsive-compulsive behaviors...
bp nd patients prior mesocorticolimbic 2/3 disease healthy hcs parkinson trait impulsivity pd Leer másBACKGROUND: Parkinson's disease (PD) etiology is not well understood. Reported inverse associations with smoking and coffee consumption prompted the investigation of alcohol consumption as a risk fact...
prospective parkinson consumption Leer másParkinson's disease (PD) is the second most prevalent neurodegenerative disease of the central nervous system, with an estimated 5 000 000 cases worldwide. Historically characterized by the progressiv...
studies system neurons inhibitors demonstrate c‐abl α‐synuclein pathology disease parkinson Leer másMitochondrial impairment is a hallmark feature of neurodegenerative disorders, such as Parkinson disease, and PRKN/parkin-mediated mitophagy serves to remove unhealthy mitochondria from cells. Notably...
parkinson mitochondria disease drosophila degradation probiotics mitophagy Leer másInternational audience; The appearance of the biomarkers in body fluids like blood, urine, saliva, tears, etc. can be used for the identification of many diseases. This article aimed to ...
alzheimer diseases biomarker parkinson molecularly imprinted polymers disease biomarkers Leer másBACKGROUND: Synucleinopathies such as Parkinson ´s disease (PD), Dementia with Lewy bodies (DLB) and Multiple System Atrophy (MSA) are characterized by deposition of misfolded and aggregated α-synucle...
synucleinopathies model trial participants subjects multiple dose safety exposure anle138b healthy parkinson mg Leer másComputing photo-z for AGN is challenging, primarily due to the interplay of relative emissions associated with the SMBH and its host galaxy. SED fitting methods, effective in pencil-beam surveys, fa...
photometric sed photo-z agn astrophysics Leer másLow-mass emission-line stars belong to various evolutionary stages, from pre-main-sequence young stars to evolved stars. In this work, we present a catalog of late-type (F0 to M9) emission-line star...
sample late-type emission-line sources Leer másThe advent of next-generation photometric and spectroscopic surveys is approaching, bringing more data with tighter error bars. As a result, theoretical models will become more complex, incorporatin...
angular blast astrophysics Leer másWe numerically examine dynamo action generated by a flow of an electrically conducting fluid in a precessing cylindrical cavity. We compare a simplified kinematic approach based on the solution of t...
kinematic remains local energy small-scale action magnetic astrophysics Leer másThe microphysics of the intracluster medium (ICM) in galaxy clusters is still poorly understood. Observational evidence suggests that the effective viscosity is suppressed by plasma instabilities th...
medium galaxies expected kpc viscosity icm Leer másRelative distances between a high-redshift sample of Type Ia supernovae (SNe~Ia), anchored to a low-redshift sample, have been instrumental in drawing insights on the nature of the dark energy drivi...
sne~ia astrophysics energy dark systematic Leer másWe introduce MEGATRON, a new galaxy formation model for cosmological radiation hydrodynamics simulations of high-redshift galaxies. The model accounts for the non-equilibrium chemistry and heating/c...
stellar feedback model high-redshift star Leer másSupernova remnants (SNRs) carry vast amounts of mechanical and radiative energy that heavily influence the structural, dynamical, and chemical evolution of galaxies. To this day, more than 300 SNRs ...
clusters astrophysics Leer másThe Planck mission provided all-sky dust emission maps in the submm to mm range at an angular resolution of 5'. In addition, some specific sources can be observed at long wavelengths and higher reso...
37 planck herschel data mm galactic environments wavelengths resolution dust Leer másThe X-ray transient, Swift J1727.7-1613 was first detected on 24 August 2023 by Swift/BAT and INTEGRAL. We investigated data from the Neutron star Interior Composition Explorer (NICER) and the Neil ...
2023 radii qpos evolution Leer másExoplanet exploration has revealed that many$\unicode{x2013}$perhaps most$\unicode{x2013}$terrestrial exoplanets formed with substantial H$_2$-rich envelopes, seemingly in contrast to solar system t...
atmosphere erosion model atmospheres Leer másOT 081 is a well-known, luminous blazar that is remarkably variable in many energy bands. We present the first broadband study of the source which includes very-high-energy (VHE, $E>$100\,GeV) $\gam...
blazar model vhe source emission $\gamma$-ray Leer másRecent observations have revealed rare, previously unknown flashes of cosmic radio waves lasting from milliseconds to minutes, and with periodicity of minutes to an hour [1-4]. These transient radio...
stars emission astrophysical astrophysics ilt j1101+5521 radio white orbital Leer másA simple model for the X-ray weakness of JWST-selected broad-line AGNs is proposed under the assumption that the majority of these sources are fed at super-Eddington accretion rates. In these condit...
super-eddington astrophysics Leer másMerging supermassive black hole (SMBH) binaries will likely be surrounded by a circumbinary accretion disk. Close to merger, gravitational radiation-driven inspiral will happen on timescales faster ...
circumbinary astrophysics flux disk accretion magnetic Leer másThe goal of this project is to construct an estimator for the masses of supermassive black holes in active galactic nuclei (AGNs) based on the broad Halpha emission line. We make use of published re...
supermassive black mass halpha Leer másWe report the observation of the transiting planet TOI-942c, a Neptunian planet orbiting a young K-type star approximately 50 Myr years old. Using Keck/HIRES, we observed a partial transit of the pl...
planet toi-942c Leer másThe anions C$_7$N$^-$ and C$_{10}$H$^-$ are the two longest of the linear (C,N)-bearing and (C,H)-bearing chains which have so far been detected in the Interstellar Medium. In order to glean informa...
linear interaction interstellar collision terms rate inelastic astrophysics anions coefficients h$_2$ Leer másDark matter (DM), in spite of being stable or long-lived on cosmological scales, can decay in the early Universe due to finite-temperature effects. In particular, a first order phase transition (FOP...
asymmetry dm Leer másIn this study, we investigate gravitational lensing within modified gravity frameworks, focusing on the Hu-Sawicki $f(R)$ and normal branch Dvali-Gabadadze-Porrati (nDGP) models, and we compare thes...
models gravitational gravity modified Leer másWe present a way to capture high-information posteriors from training sets that are sparsely sampled over the parameter space for robust simulation-based inference. In physical inference problems, w...
inference information Leer másRings are complex structures surrounding giant planets and some minor bodies in the Solar System. While some formation mechanisms could also potentially foster their existence around (regular or irr...
moons astrophysics iapetus mechanisms solar system rings Leer másRadially extended disk winds could be the key to unlocking how protoplanetary disks accrete and how planets form and migrate. A distinctive characteristic is their nested morphology of velocity and ...
winds nested astrophysics Leer másClose-proximity exploration of small celestial bodies is crucial for the comprehensive and accurate characterization of their properties. However, the complex and uncertain dynamical environment aro...
close-proximity systems uncertainty propagation astrophysics Leer másIn this paper, we carry out multiwavelength and multiview observations of the prominence eruption, which generates a C2.3 class flare and a coronal mass ejection (CME) on 2023 March 7. For the first...
eruptive cone degrees Leer másSIMPLE SUMMARY: Maternal care in dogs and its impact on the behavioural development of puppies has become the subject of growing research interest. In order to determine the effects of maternal care o...
0 study reared environment puppies maternal associated behavioural test care amount social Leer másThe objective of WP7 is to study, from the perspective of EU citizenship, specific problems EU citizens face in exercising civil rights and liberties in areas which fall within the scope of EU law, bu...
scope civil sense etc study citizen journalism eu political freedom citizenship legal rights media Leer másAIMS: During the early phase of the COVID-19 pandemic, general surgeons were advised to apply conservative management/open surgery for appendicitis. This single NHS centre study has explored the resul...
study covid-19 significant patients pandemic mean Leer másBACKGROUND: Institutional delivery is the cornerstone reducing maternal mortality. Community-based behavioral change interventions are increasing institutional delivery in developing countries. Yet, t...
compared study 0 signs danger attend effect attending delivery institutional attended 95%ci conference women’s pregnant women Leer másCerebral reperfusion injury is the major complication of mechanical thrombectomy (MT) for acute ischemic stroke (AIS). Contrast extravasation (CE) and intracranial hemorrhage (ICH) are the key radiogr...
cerebral reperfusion injury contrast extravasation posterior circulation symptomatic intracranial hemorrhag... acute ischemic stroke mechanical thrombectomy circulation ci ac functional extravasation contrast study anterior posterior < 0 injury cerebral reperfusion stroke 01 pc ich patients mt Leer másPURPOSE: This study assessed the combined accuracy of optic nerve sheath diameter (ONSD), strain ratio (SR), and shear wave elastography (SWE) of the optic nerve (ON) in patients with idiopathic intra...
mm study values controls 0 patients sr accuracy nerve optic onsd papilledema iih swe Leer másOBJECTIVES: Physical activity in the general population is considered too low, and this is true for pregnant women. Moderate physical activity during pregnancy have many benefits for the mother and th...
women study level activity physical pregnancy 95% ci Leer másBACKGROUND: Xiamen is a pilot city in China for hierarchical diagnosis and treatment reform of non-communicable diseases, especially diabetes. Since 2012, Xiamen has implemented a program called the “...
china increased study 2012 policy team-based three-in-one model health diabetes hospitals treatment care patients Leer másBackground The aim of this study was to determine the 25-hydroxy vitamin D (25(OH)D) levels in age-related macular degeneration (AMD) patients. Methods Age-related macular degeneration (AMD) patients ...
vitamin d age-related macular degeneration 25-hydroxy vitamin d vitamin d deficiency 25(oh)d macular age-related study degeneration healthy vitamin 93 levels Leer másBACKGROUND: More than 50% of Africa’s population lives in rural areas, which have few professional health workers. South Africa has adopted task shifting health care to Community Health Workers (CHWs)...
cohort child care sc received study birth home workers south mothers visits rural health Leer másThis work is devoted to the study of the shear viscosity by numerical simulation of equilibrium classical molecular dynamics with a particular attention to the influence of high pressur...
fluids molecular mélanges metals mixtures numerical viscosity conditions study influence étude simulation relation viscosité stokes-einstein Leer másBackground Sexual health is one of the main areas of health and basic human rights which has been paid less attention in schizophrenia. Most studies have focused on sexual dysfunction rather than the ...
sexual needs schizophrenia psychiatric nursing descriptive phenomenology qualitative study study descriptive health people sexual schizophrenia Leer másBackground Knee osteoarthritis (KOA) causes not only pain, stiffness, and dysfunction of the knee, but also the reduction of the joint range of motion (ROM). This study explored the demographic and ra...
knee osteoarthritis symptoms range of motion study osteoarthritis age symptomatic demographic symptoms factors koa knee 05 p < 0 womac Leer másBACKGROUND: Older patients with cancer require specific and individualized management. The 3-group Multidimensional Prognostic Index (MPI) based on the Comprehensive Geriatric Assessment (CGA) has sho...
study tumor prospective index cohort 1-year sites geriatric mpi cancer prognostic Leer másRecent advances in Natural Language Interfaces (NLIs) and Large Language Models (LLMs) have transformed our approach to NLP tasks, shifting the focus towards a more Pragmatics-based approach. This s...
study proactive Leer másBACKGROUND: Dietary assessment is the first step of dietary modification in community-based interventional programs. This study was performed to validate a simple food frequency questionnaire (SFFQ) f...
selected study sffq reproducibility intake validity correlation validation questionnaire 0 frequency assessment ffq dietary Leer másBACKGROUND: Systems biology aims to analyse regulation mechanisms into the cell. By mapping interactions observed in different situations, differential network analysis has shown its power to reveal s...
ripening reveals sense mechanisms method specific study genes regulation as-impacted data interactions Leer másBackground Communities That Care (CTC) is an approach to translate prevention science into the practice of community-based health promotion. Through training and tools, CTC supports communities to bui...
kommunale gesundheitsförderung systemveränderung evidenzbasierte prävention und ges... effektivität quasi-experimentelle studie community-based health promotion system change evidence-based prevention and heal... effectiveness quasi-experimental study adoption merkmalen intersectoral ist characteristics ergebnisse health study übernahme befragten kommunalen wissenschaftsbasierter ctc der und prevention die von vk ik science-based ic community cc collaboration care den support communities Leer másInternational audience; Background: Since the first launch of a biosimilar recombinant follicle stimulating hormone (rFSH), Bemfola®, in Europe in 2014, it has been possible to study in ...
ovarian gonal-f® real world according stimulation study biosimilar increasing including reola dose clbr art mesh Leer másInternational audience; Medial vascular calcification (MVC) is a highly prevalent disease associated with a high risk of severe, potentially lethal, complications. While animal studies m...
[sdv study cells sciences aortic Leer másThe unicellular marine diatom Phaeodactylum tricornutum accumulates up to 35% eicosapentaenoic acid (EPA, 20:5n3) and has been used as a model organism to study long chain polyunsaturated fatty acids ...
acyl study lc‐pufa epa tricornutum biosynthesis Leer más(1) Background: Container orchestration frameworks provide support for management of complex distributed applications. Different frameworks have emerged only recently, and they have been in constant...
study common kubernetes functional feature unique container orchestration frameworks features Leer másPlasmonic nanostructures based on noble metals are used as photosensors in biology, as active surfaces for photochemical detection (surface enhanced Raman spectroscopy), to manipulate l...
nanoparticules experimental containing propriétés systems étudié résultats account contenant systèmes proposé permettant modeling approach studied comportement using nanoparticles avons électrons chauds interactions génération modèle proposed optique model optical plasmonic hot generation materials electron study photocatalysis numerical behavior matériaux electrons Leer másOpinion mining has emerged as a hot topic in the machine learning community due to the recent availability of large amounts of opinionated data expressing customer's attitude towards me...
entity granularity annotations building underlying study statistical models questions différentes representation joint architecture opinion output apprentissage based model able complexity objects données advantage resulting thesis jointly predict prédiction modèles structured predictors valence hierarchical learning Leer másThis thesis is concerned with two problems in real and complex hyperbolic geometry. The first problem is the study of geometric structures on moduli spaces of flat metrics on the sphere...
plates discrets real flat thesis singularités étudie singularities thèse hyperbolic hyperbolique complex moduli metrics complexe study geometry métriques spaces espaces structure Leer másBackground Giant cell tumor of soft tissue is a low malignant uncommon neoplasm, with histologic features and immunophenotype similar to its bone counterpart. Primary giant cell tumor of soft tissue i...
thyroid gland tumor of soft tissue giant cell tumor of soft tissue immunohistochemistry differential diagnosis cells soft tissue cell thyroid giant tumor Leer másBACKGROUND: The intrapulmonary ectopic thyroid gland is exceedingly rare since the ectopic thyroid was discovered. Only eight cases have been reported in the worldwide literature. We present a case of...
lung goiter nodular ectopic thyroid Leer másBackground Radiation shielding in radiology has historically been achieved with lead; however, there has been an increasing demand for radiation shielding to be more environmentally friendly. Barium h...
radiation shield barium sulphate panoramic radiography radiation safety shielding eye radiography reduction shield radiation dose thyroid Leer másIn 2016, the American Thyroid Association published a statement on remote-access thyroid surgery claiming that it should be reserved to patients with thyroid nodule ≤ 3 cm, thyroid lobe < 6 cm and wit...
robotic transaxillary thyroidectom... robot-assisted surgery remote-access thyroidectomy thyroidectomy thyroid thyroidectomy thyroiditis robotic transaxillary patients = 0 Leer másBACKGROUND: To prevent thyroid storm and ensure surgical safety, it is imperative to regulate excessive thyroid hormone levels in patients with thyrotropin-secreting pituitary adenomas (TSHoma) prior ...
thyroid surgery study patients surgical octreotide treatment Leer másRadioactive iodine was the first isotope engaged in a theranostic approach, initially used to treat thyroid diseases. The first radioiodine treatments were done in the early 1940s. Based on the high e...
theranostic radioiodine thyroid cancer thyroid carcinoma papillary follicular therapy diseases cancer therapy radioiodine thyroid Leer másBACKGROUND: Cases of subacute thyroiditis (SAT) after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination have been reported. A human leukocyte antigen (HLA) allele, HLA-B*35, app...
fever blood pain involved pathogenesis gd hla-b*35 serum typing thyrotoxicosis revealed thyroid 01 alleles hla developed vaccination sars-cov-2 sat Leer másBackground Microcalcifications are suggested to be an indicator of thyroid malignancy, especially for papillary thyroid carcinoma (PTC), nonetheless, the association between macrocalcification and PTC...
thyroid nodule papillary thyroid carcinoma macrocalcification fine needle aspiration biopsy proto-oncogene proteins b-raf v600... significantly efficiency mutation 100 diagnostic ptc nodules macrocalcification v600e thyroid vs Leer másPurpose To perform a molecular profiling of the metastases from papillary thyroid carcinomas (PTCs) and poorly differentiated thyroid carcinomas (PDTCs). Methods We retrieved and analyzed the molecula...
papillary thyroid carcinomas poorly differentiated thyroid carc... dna sequencing somatic mutations copy number alterations distant metastasis bone fga 3% thyroid carcinomas < 0 lnms vs frequency 05 Leer másPurpose Dosimetry is rarely performed for the treatment of differentiated thyroid cancer patients with Na[^131I]I (radioiodine), and information regarding absorbed doses delivered is limited. Collecti...
multicentre study dosimetry nai thyroid cancer administered performed multi-centre data median differentiated whole-body respectively dosimetry na[^131i]i cancer 0 thyroid absorbed doses Leer másBACKGROUND: Papillary thyroid carcinoma (PTC) accounts for about 60% of adult thyroid carcinoma and generally has an excellent prognosis. Primary squamous cell carcinoma of thyroid (PSCCT) is a rare t...
cell prognosis atc-scc thyroid pdtc carcinoma subtype Leer másBackground Graves’ disease is the most common cause of thyrotoxicosis worldwide. Patient characteristics may vary according to ethnicity, iodine status, and age. Studies on characterization of Graves’...
graves’ disease hyperthyroidism egypt africa trab’s thyroid common positive patient 7% 17 disease graves’ patients Leer másBackground Sleeve gastrectomy (SG) continues to be one of the most popular bariatric procedures all over the world. Thyroid-stimulating hormone (TSH) frequently shows a slight elevation in patients wi...
obesity laparoscopic sleeve gastrectomy thyroid functions gastrectomy 001 obesity correlated sleeve hba1c tsh thyroid patients 12-month preoperative sg functions study = 0 levels Leer másINTRODUCTION: The invasion of important structures in locally advanced thyroid cancer (LATC) hinders radical resection, increases the risk of recurrence and even prevents surgery. Creating the opportu...
thyroid efficacy trial response rate latc therapy cancer neoadjuvant study Leer másBackground Anaplastic thyroid carcinoma (ATC) is a rare but aggressive malignancy, which accounts for only 1–2% of all thyroid cancers. The median overall survival (OS) time for all stages patients is...
anaplastic thyroid carcinoma surgery radiation therapy chemotherapy = 0 vs analysis study months hr = 0 001 survival chemotherapy 95% ci adjuvant 0 anaplastic overall ivc combined patients stage thyroid atc Leer másBACKGROUND: Recent investigations have highlighted autoimmune origins and abnormal immune responses; particularly those related to T cell-mediated immunity and elevated T lymphocyte cells in the oral ...
thyroid atd patients ras Leer másBACKGROUND: To prevent thyroid storm and ensure surgical safety, it is imperative to regulate excessive thyroid hormone levels in patients with thyrotropin-secreting pituitary adenomas (TSHoma) prior ...
thyroid surgery study patients surgical octreotide treatment Leer másPurpose It is widely accepted that patients experience weight gain after total thyroidectomy, and preventive measures should be recommended. Methods A prospective study was designed to assess the effi...
body weight gain thyroidectomy diet counseling obesity bmi post-thyroidectomy significant intervention pre-surgery counseling weight t2 t1 = 0 gain thyroid patients Leer másBACKGROUND: Yersinia enterocolitica is a gram-negative zoonotic bacterial pathogen that is typically transmitted via the fecal-oral route. The most common clinical manifestation of a Y. enterocolitica...
adenoma follicular left gland enterocolitica thyrotoxicosis thyroid abscess Leer másMedullary thyroid carcinoma (MTC) presents as a thyroid nodule but its correct diagnosis is complicated by some controversies. Firstly, calcitonin is the most accurate diagnostic marker but its routin...
nodulo tiroideo carcinoma midollare tiroideo ecografia tirads diagnosi thyroid nodule medullary thyroid carcinoma ultrasound tirads diagnosis systems rsss/tiradss dati recently una del che con performance nella di thyroid mtc diagnosis cmt carcinoma Leer másPURPOSE: We present a case of Type 1 (lipogenic) Thyroid Eye Disease (TED) and our aim is to describe an atypical presentation of a rare orbital process. OBSERVATIONS: A man in his 50s presented with ...
eye presentation ted hyperglobus lipogenic thyroid disease Leer másBackground Thyroid cancer is one of the most common cancers of the endocrine system. The incidence of this cancer has increased in many countries. Many cases of thyroid cancer do not have any symptom...
thyroid neoplasms incidence epidemiology risk factors global incidence low physical activity modifiable cancer factors thyroid risk correlation study asir Leer másBACKGROUND: Papillary thyroid carcinoma PTC is the most prevalent of all thyroid carcinomas. On the other hand, Hashimoto’s thyroiditis (HT), as part of the spectrum of autoimmune thyroid diseases, is...
pathology hashimoto compared study based thyroiditis ht ptc invasion patients tumor thyroid Leer másBACKGROUND: Recent investigations have highlighted autoimmune origins and abnormal immune responses; particularly those related to T cell-mediated immunity and elevated T lymphocyte cells in the oral ...
thyroid atd patients ras Leer másImmunotherapy medicines (immune checkpoint inhibitors, ICIs) that work directly on the immune system have shown vastly increased survival for people with cancer in phases 2 and 3 clinical studies duri...
immunotherapy thyroid dysfunction cancer management ipilimumab nivolumab pd-1 inhibitors icis review cancer treatment thyroid Leer másObjectives To determine a data-based optimal annual radical cystectomy (RC) hospital volume threshold and evaluate its clinical significance regarding perioperative mortality, complications, length of...
radical cystectomy bladder cancer urothelial carcinoma perioperative outcomes hospital caseload data 95% ci p < 0 perioperative 001 threshold optimal rc centers stay mortality patients inpatient Leer másContexte Bien que l’orchidopexie soit recommandée en cas de cryptorchidie afin de préserver la fertilité masculine, une azoospermie non obstructive (NOA) peut survenir à l’âge adulte. Heureusement, un...
stepwise mini-incision microdissec... microdissection testicular sperm e... non-obstructive azoospermia cryptorchidism sperm retrieval rate extraction de spermatozoïdes testi... extraction de spermatozoïdes testi... azoospermie non obstructive cryptorchidie taux de récupération de spermatozo... history résultats study étapes l’âge technique time orchidopexy mtese sperm noa spermatozoïdes = 0 0 au stepwise l’orchidopexie testicular cryptorchidism patients srr Leer másBackground Reference blood pressure (BP) values for Japanese children based on a large number of measurements by auscultation have not yet been established. Methods This was a cross-sectional analysis...
blood pressure reference value auscultation aneroid sphygmomanometer lms method polynomial regression model data 2-year-old using japanese lms regression values model auscultation study reference Leer másGenetische Analysen an Patienten mit fortgeschrittenem Prostatakrebs entwickelten sich in den letzten Jahren zu einem wichtigen Bestandteil der Diagnostik. Aufgrund der sensiblen Daten und potenzielle...
genetische tests prostatakrebs brca1/2 gendiagnostikgesetz gentechnikgesetz genetic tests prostate cancer brca1/2 genetic diagnosis act genetic engineering act dass sich cancer performed auf der und genetic testing die Leer másBackground Retroperitoneal liposarcoma (RPLPS), a rare tumor, is often treated using surgical procedures as the first choice for treatment. However, there is no consensus on the scope of surgical rese...
recurrence metastasis dedifferentiated liposarcoma combined organ resection targeted therapy lps dedifferentiated tumors left surgical tumor rplps retroperitoneal Leer másThere is growing evidence that endocrine disruptive chemicals have deleterious effects on sexual and reproductive function. To examine subjective sexual functions in human females and their relationsh...
subjective urban perinatal androgenization females effects effect vs rural sexual function exposure mono age Leer másObjectives To identify the predictive factors of prostate cancer extracapsular extension (ECE) in an institutional cohort of patients who underwent multiparametric MRI of the prostate prior to radical...
prostate cancer multiparametric magnetic resonance... radical prostatectomy extracapsular extension predictive models nomogram prostate 0 patients ece mri predictive Leer másBackground Multiple Sclerosis (MS) is an often debilitating disease affecting the myelin sheath that encompasses neurons. It can be accompanied by a myriad of pathologies and adverse effects such as n...
multiple sclerosis neurogenic overactive bladder functional mri transcranial magnetic stimulation neural ms nlutd Leer másBackground In clinical trials targeting early chronic kidney disease (CKD), eGFR slope has been proposed as a surrogate endpoint for predicting end-stage kidney disease (ESKD). However, it is unclear ...
egfr slope chronic kidney disease surrogate endpoint end stage kidney disease surrogate endpoint chronic disease kidney slope ckd Leer másPurpose To evaluate perioperative parameters, clinical outcomes, and the learning curve of holmium laser enucleation of the prostate (HoLEP) of a single surgeon in 500 consecutive cases. Methods Demog...
holep en-bloc prostatic hyperplasia learning curve endoskopic enucleation holmium laser surgeon en-bloc technique test clusters consecutive < 0 001 500 curve learning vs enucleation time cluster Leer másBackground Prostate cancer exhibits a very diverse behaviour, with some patients dying from the disease and others never needing treatment. Active surveillance (AS) consists of periodic PSA assessment...
active surveillance prostate cancer prospective cohort include impact strategy patients prostate low-risk public health Leer másBackground Urinary proteomics identifies the totality of urinary proteins and can therefore help in getting an early and precise diagnosis of various pathological processes in the kidneys. In infants,...
urinary proteomics urine collection liquid chromatography-mass spectro... chronic kidney disease infants correlation using infants urine proteomics urinary clean collection catch proteins Leer másObjective Functional vein end to arterial side (ETS) anastomosis uses vein side to arterial side anastomosis with distal vein ligation, which is different from traditional ETS anastomosis. To date, th...
arteriovenous fistula functional end-to-side anastomosis... anastomosis angle patency 30–50°anastomosis 12 months lowest rate study radiocephalic anastomosis = 0 angle functional 03 fistula 01 venous ppr crr near segment ets angles Leer másPurpose Circumcision is the most common surgical procedures performed in males. Medical circumcision is recommended for diseases such as phimosis, paraphimosis, balanoposthitis and common urinary trac...
circumcision clamp ring devices children suturless operation patients time circumcision Leer másRobotic flexible ureteroscopy (RFURS) has shown encouraging results in terms of stone free rate (SFR) and better ergonomics compared to conventional FURS. However, few studies have reported its outcom...
robotic flexible ureteroscopy rirs furs rfurs roboflex tetrafacta renal 0 stones median tetrafecta stone = 0 reporting treatment rfurs patients Leer másThis study explores how attitudes toward talking about sex and sexual matters influence practices regarding sexuality, sexual rights, and sexual abuse in residential institutions for people with disab...
disability sexuality sexual rights sexual abuse residential institutions greenland education managers matters regarding sex staff residents Leer másBackground The pharmacological management of hyperkalemia traditionally considered calcium or sodium polystyrene sulfonate and, since recently, the novel binders patiromer and sodium zirconium cyclosi...
patiromer sodium zirconium cyclosilicate sodium polystyrene sulfonate hyperkalemia scream zirconium duration patiromer cyclosilicate treatment 0 potassium sulfonate polystyrene sodium binders Leer másBackground Kidney and life outcomes remain unsatisfactory in patients with microscopic polyangiitis (MPA). Appropriate treatment intensity must be provided to the appropriate patients. To identify sev...
prognosis microscopic polyangiitis kidney function kidney histopathology 2 weeks poor mpa kidney treatment Leer másPurpose Testicular Germ Cell Tumors (TGCTs) are the most frequent solid malignancies in young adult men. Regardless of differences in their cell of origin, all TGCTs are considered highly curable mali...
testicular germ cell tumors cisplatin chemoresistance mlh1 rev-7 predictive tissue markers tumors cell patients’ 16 chemosensitive predictive tissue significantly tgcts associated immunohistochemical specimens positive disease chemoresistant rev-7 patients Leer másBackground There is increasing evidence that DEAD-box helicases ( DDX ) can act either as promoters or suppressors in various cancer types. Nevertheless, the function of DDX49 in prostate cancer (PCa)...
ddx49 prostate cancer prognosis proliferation apoptosis prognosis poor normal cycle proliferation patients cancer prostate knockdown ddx49 pca apoptosis Leer másThis study aimed to (1) describe male mildly intellectually disabled (MID) adolescents’ general romantic and sexual development, education experience with topics on sexuality and relationships, and fr...
sexual assault male youth sexual development learning disability risk factors netherlands experienced peer resilience pressure knowledge sexual sdv victimization attitudes Leer másBackground Hilar tumours are the renal tumours, which abut the renal artery or vein. Nephron sparing surgery (NSS) is of proven benefit among those with small renal masses. Hilar tumours are usually o...
renal tumour hilar tumour nephron sparing surgery robotic partial nephrectomy follow-up hilar nephrectomy robot-assisted nss partial time grade median surgery patients nephron sparing tumours Leer másBiological and biomedical research using Drosophila melanogaster as a model organism has gained recognition through several Nobel prizes within the last 100 years. Drosophila exhibits several advantag...
drosophila melanogaster nephrocyte podocyte model organism inter-organ communication study nephrocytes Leer másBackground To assess depression, anxiety, and other psychological disorders in adolescents with chronic kidney disease (CKD) and determine the significant factors and the effect of digital media use o...
chronic kidney disease depression anxiety adolescent disorders scales anxiety adolescents separation disorder total panic obsession ckd Leer másInternational audience; Background and aimsThe main goal of the laboratory of Parasitology at the Veterinary College of Alfort (EnvA) is to offer its expertise in parasite research and i...
parasitology detection enva activity analyses [sdv sciences diagnostic veterinary Leer másSIMPLE SUMMARY: Gut health has been a main topic in veterinary medicine research after the ban on the use of antimicrobial growth promoters. Gut health has been defined as absence/prevention/avoidance...
research analysis bibliometric veterinary gut health Leer másLarge language models (LLMs) can extract information from veterinary electronic health records (EHRs), but performance differences between models, the effect of temperature settings, and the influen...
ehrs extraction 9% 81 4% 96 iqr information veterinary performance temperature Leer másSIMPLE SUMMARY: On the one hand, veterinary ethics is a required part of veterinary education. On the other hand, the success of ethics teaching and the students’ skills concerning judgements in moral...
teaching morally tool skills ethics students veterinary moral Leer másBackground Veterinary medicines have been widely used for the prevention and treatment of animal diseases. Globally, the veterinary medicine industry is growing. However, there is a significant increa...
falsified post-marketing surveillance product information review substandard screening veterinary medicines collected samples drug treatment circulating medicines veterinary tanzania information sampled product mainland quality Leer másBackground Antibiotic resistance is a global health concern. Humans can acquire antibiotic resistance through human-to-human transmission, from the environment, via the food chain, and through the con...
antibiotic resistance public health animal health professionals veterinary respondents < 0 rwanda antibiotics 95% ci misuse professionals animal health antibiotic aor Leer másInternational audience; Veterinary practices can be stressful places for dogs. Decreasing stress during veterinary consultations is therefore a major concern, since animal welfare matter...
consultation veterinary Leer másBACKGROUND: Antimicrobial resistance (AMR) threatens our ability to treat and prevent infectious diseases worldwide. A significant driver of AMR is antimicrobial use (AMU) in human and veterinary medi...
ktt research emergence amr students antimicrobial veterinary materials communication Leer másChlamydia (C.) pecorum, an obligate intracellular bacterial species commonly found in ruminants, can also occur in pigs. However, its significance as a potential porcine pathogen, or commensal, is sti...
swiss period veterinary fattening loads suis Leer másSIMPLE SUMMARY: The article summarizes the current knowledge on factors related to pregnancy, parturition, and newborns that affect the health status of a puppy and determine its chances for survival ...
perinatal current knowledge health veterinary review Leer másBackground: Limited universally-adopted data standards in veterinary medicine hinder data interoperability and therefore integration and comparison; this ultimately impedes the application of existi...
medicine terms information names ontology vbo data veterinary breed Leer másBackground The English Cocker Spaniel (ECS) is a common family dog in the UK. This study aimed to describe demography, morbidity, and mortality in ECS under primary veterinary care in the UK during 20...
vetcompass electronic patient record epr breed dog epidemiology primary-care veterinary pedigree english cocker spaniel affecting average spaniels iqr median females ecs 95% veterinary ci males periodontal prevalence age dogs breed cocker disorders english solid-coloured information uk 2016 death study aggression common Leer másBackground: Antimicrobial stewardship activities are essential to improve prudent antimicrobial use. The aim of the present study was to evaluate changes in antimicrobial prescriptions in cats after t...
2018 veterinary therapy 1% compliance 2] overall 0] [26 7% prescriptions stewardship cats private prudent practices Leer másSIMPLE SUMMARY: COVID-19 has impacted veterinary medicine and cat guardians in numerous ways. The purpose of this study was to better understand cat guardians’ fears and concerns pertaining to veterin...
ability obtain impact veterinary concerns Leer másEarly disease detection in veterinary care relies on identifying subclinical abnormalities in asymptomatic animals during wellness visits. This study introduces an algorithm designed to distinguish ...
ci 95% visit classification 0 algorithm veterinary visits Leer másThis paper explores the innovative use of simulation environments to enhance data acquisition and diagnostics in veterinary medicine, focusing specifically on gait analysis in dogs. The study harnes...
acquisition medicine veterinary Leer másBackground Communication skills are a necessary competency in veterinary medicine, and shared decision-making (SDM) between practitioners and patients is becoming increasingly important in veterinary ...
veterinary medicine veterinary communication shared decision-making decision-making preference study medicine 0 results conducted relationship decision-making veterinary owners sdm-q-9 veterinarians sdm-q-doc sdm pet Leer másSIMPLE SUMMARY: Despite developments in animal welfare science regarding perioperative pain management in calves (Bos taurus), there are concerns that current knowledge has not been adopted in practic...
zealand despite management perceptions veterinary current pain calves perioperative Leer másSIMPLE SUMMARY: Transferrin receptor one (TFR-1), recognized by ferritin, is overexpressed in many tumor cells. This feature has been exploited to produce a selective overload of drugs within tumor ce...
vitro drug nanocage study tumors animal engineered compared veterinary cells mammary expression tfr-1 Leer másBACKGROUND: Antimicrobial resistance (AMR) threatens our ability to treat and prevent infectious diseases worldwide. A significant driver of AMR is antimicrobial use (AMU) in human and veterinary medi...
ktt research emergence amr students antimicrobial veterinary materials communication Leer másInternational audience; Antimicrobial resistance (AMR) is a global public health threat driven by a combination of factors, including antimicrobial use (AMU) and interactions among micro...
perspective medicine development amu-v amr resistance amr-v private model veterinary public antimicrobial Leer másInternational audience; In this study, the impact of coronavirus disease 2019 pandemic crisis on veterinary education in selected members of the Mediterranean Networkof Veterinary Educat...
teaching region pandemic establishments veterinary Leer másInternational audience; Public–private partnerships (PPPs) in the veterinary domain are joint approaches in which public veterinary services and private actors such as private veterinari...
health veterinary ppp actors domain private Leer másInternational audience; Antimicrobial resistance (AMR) should be tackled through a One Health approach, as stated in the World Health Organization Global Action Plan on AMR. We describe ...
european medicine veterinary surveillance amr ears-vet Leer másAgriculture in general, and livestock production in particular, serve as a livelihood source for many people in sub-Saharan Africa (SSA). In many settings, lack of control of infectious diseases hampe...
ssa controlling evaluated effective applied veterinary and/or vaccination infectious diseases Leer másAirway remodeling is a key characteristic of allergic asthma. Epithelial-mesenchymal transition (EMT) induced by various factors, particularly transforming growth factor (TGF)-β1, orchestrates airway ...
deficiency ko lincr-ppp2r5c asthma allergic remodeling Leer másINTRODUCTION: Secukinumab (SEC) has been shown to be highly effective and safe in the treatment of moderate to severe plaque psoriasis (PsO), but data on SEC’s long-term drug survival are limited. AIM...
4% patients psoriasis sec drug Leer másBACKGROUND: There are some adverse effects with coronavirus disease 2019 (COVID-19) vaccines, but the impact of COVID-19 vaccination on attacks in hereditary angioedema (HAE) is not well defined. OBJE...
0 ± attack vaccination hae attacks doses covid-19 Leer másBACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic impacted various parts of society, including Japanese children with allergies. OBJECTIVE: This study investigated risk factors for pediatri...
parents allergens children school comments dermatitis total disease pandemic covid-19 factors home pediatric allergies Leer másBACKGROUND: The prevalence of asthma among children has been on the rise worldwide, leading to significant morbidity and mortality. Our study was conducted to determine the prevalence of asthma and it...
wheezing arabia 6% reported study children jazan region saudi factors risk prevalence asthma Leer másPURPOSE: Cluster analyses on inflammatory markers of chronic rhinosinusitis (CRS) in Asians from multicenter data are lacking. This multicenter study aimed to identify the endotypes of CRS in Koreans ...
mediators phenotype levels crswnp ige t3 crs t2 cluster endotypes Leer másBackground: In Europe, North America, and Australia, 5% to 10% of the population are now classified as penicillin (β-lactam) allergic. Only ~ 10% of these questionable diagnoses, mostly made in childh...
penicillin suspected using questionable allergy antibiotic bla Leer másINTRODUCTION: Data on the use of remote spirometry are limited in the pediatric population. We sought to assess the feasibility and accuracy of a digital turbine spirometer, Medical International Rese...
participants correlation mean research tests using study 95% turbine agreement devices fvc fev mir 0 Leer másAllergen immunotherapy (AIT) is a causative treatment for various allergic diseases such as allergic rhinitis, allergic asthma, and bee venom allergy that induces tolerance to offending allergens. The...
guideline immunotherapy allergy guidelines Leer másINTRODUCTION: Upadacitinib, an oral selective-JAK1 inhibitor, has been used in clinical trials to treat atopic dermatitis (AD). AIM: To evaluate the efficacy and safety of upadacitinib in moderate-to-...
treatment moderate-to-severe ad trials Leer másAllergic contact dermatitis is one of the most frequent occupational skin diseases. Targeted allergen avoidance can only be achieved by identification of the causative allergen. Therefore, patch testi...
occupational testing test patch Leer másINTRODUCTION: Asthma is one of the common chronic polygenic inflammatory diseases. Genome wide association studies have identified ADAM33 as an asthma candidate gene. The present study investigated po...
haplotype controls in-silico sensitivity found differed patients association 02 bengal india patient 0001 west analysed polymorphisms asthma p = 0 analysis p < 0 using significantly t1 adam33 t2 significant adult Leer másBACKGROUND: The impact of non‐pharmacological interventions (NPIs) on asthma prevention and management is insufficiently examined. We aim to comprehensively evaluate and synthesize existing evidence r...
review adulthood adults quality various management reviews interventions course prevention npis control evidence Leer másAllergic rhinitis (AR) is a common disease, characterized by typical symptoms and type 2 inflammation. Standard treatment is usually effective and safe, and most medications are available as over-the-...
symptoms vas control ar Leer másBACKGROUND: Bone and joint infections are common in children, particularly those under 10 years of age. While antimicrobial therapy can often successfully treat these infections, surgical drainage may...
age antimicrobial antibiotics days 16 drug infections children bone joint mean symptoms syndrome dress Leer másBACKGROUND: Severe Congenital Neutropenia type 4 (SCN4), is a rare autosomal recessive condition, due to mutations in the G6PC3 gene. The phenotype comprises neutropenia of variable severity and accom...
neutropenia congenital Leer másIn this article, we discuss the importance of real-world data in the treatment of patients with asthma and specifically the role of maintenance and reliever therapy (MART) with beclometasone dipropion...
study asthma Leer másBACKGROUND: The proteolytic activities of house dust mite (HDM) allergens are involved in the pathogenesis of asthma by cleaving T-junction protein complexes, increasing the permeability of airway epi...
protease aat inhibitory concentration 0 asthma activity serum 05 Leer másFood protein induced enterocolitis syndrome (FPIES) belongs to a group of IgE-independent food allergies. It is the domain of paediatric patients, but it can also occur in adults. In this disease ther...
adults food disease Leer másBackground: Allergen-specific immunotherapy (AIT) is currently the only treatment with potential long-term disease-modifying effects for patients suffering from allergic diseases such as allergic rhin...
mechanisms cells allergen-specific regulatory Leer másBACKGROUND: Patients with severe uncontrolled asthma (SUA) overwhelmingly contribute to the economic burden of asthma and may require biologic therapy. However, the impact of the CoronaVirus Disease o...
health covid-19 biologic specialists pcps care patients pandemic decreased asthma costs Leer másINTRODUCTION: Asthma is a pulmonary disease and its pathogenesis is involved with immune cells and related signalling pathways. Alpha-alumina is material for therapy applications and mucus adhesion pr...
effect mucus vip Leer másNot available
immunology allergology society Leer másMorphea en coup de sabre and progressive hemifacial atrophy are extremely rare connective tissue disorders causing facial deformity. In extreme cases, morphological disorders are accompanied by sympto...
system atrophy stomatognathic morphea tissue Leer másBACKGROUND: Bone and joint infections are common in children, particularly those under 10 years of age. While antimicrobial therapy can often successfully treat these infections, surgical drainage may...
age antimicrobial antibiotics days 16 drug infections children bone joint mean symptoms syndrome dress Leer másUtilizamos cookies y otras tecnologías similares para :
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