Documentdetail
ID kaart
oai:pubmedcentral.nih.gov:1100...
Onderwerp
Case ReportAuteur
Klein, Benjamin Treudler, ReginaLangue
enEditor
Dustri-Verlag Dr. Karl Feistle
Categorie
Allergologie Select
Jaar
2024
vermelding datum
10-06-2024
Trefwoorden
eosinophilic dupilumabBeschrijving
Abstract.
Background: Eosinophilic esophagitis (EoE) is an inflammatory disease of the esophagus that belongs to the spectrum of Th2-mediated diseases.
It is often associated with atopic comorbidities such as allergic asthma (AA) and poses a therapeutic challenge.
Case report: We report on a 43-year-old patient with EoE and AA who did not show sufficient therapeutic control despite standard therapy.
We started treatment with dupilumab, whereupon both EoE and AA rapidly improved and complete symptom resolution could be documented.
The response to dupilumab was assessed by laboratory monitoring and gastroscopy, which showed a reduction of markers of type II inflammation and eosinophilic infiltrates in the esophagus.
Summary: Our report emphasizes the effective and safe use of dupilumab as a treatment option for EoE with concomitant beneficial effects on AA.
Klein, Benjamin,Treudler, Regina, 2024, Rapid response to dupilumab in an adult patient with eosinophilic esophagitis and allergic asthma, Dustri-Verlag Dr. Karl Feistle
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