Documentdetail
ID kaart
oai:pubmedcentral.nih.gov:8879...
Onderwerp
Themed Section: Neurodegenerative ...Auteur
Banerjee, Rajashree Rai, Arushi Iyer, Shreyas M. Narwal, Sonia Tare, MeghanaLangue
enEditor
John Wiley and Sons Inc.
Categorie
Animal Models and Experimental Medicine
Jaar
2022
vermelding datum
16-10-2023
Trefwoorden
parkinson alzheimer models diseaseBeschrijving
Alzheimer's disease and Parkinson's disease are two of the most prevalent and disabling neurodegenerative diseases globally.
Both are proteinopathic conditions and while occasionally inherited, are largely sporadic in nature.
Although the advances in our understanding of the two have been significant, they are far from complete and neither diagnosis nor the current practices in treatment and rehabilitation is adequately helpful.
Animal models have historically found application as testing beds for novel therapeutics and continue to be valuable aids in pharmacological research.
This review chronicles the development of those models in the context of Alzheimer's and Parkinson's disease, and highlights the shifting paradigms in studying two human‐specific conditions in non‐human organisms.
Banerjee, Rajashree,Rai, Arushi,Iyer, Shreyas M.,Narwal, Sonia,Tare, Meghana, 2022, Animal models in the study of Alzheimer's disease and Parkinson's disease: A historical perspective, John Wiley and Sons Inc.
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