detalle del documento
IDENTIFICACIÓN
doi:10.1186/s13000-024-01515-z...
Autor
Wang, Mengyan Cui, Yahui Shi, Jinchuan Yan, JunLangue
enEditor
BioMed Central
Categoría
Medicine & Public Health
Año
2024
fecha de cotización
10/7/2024
Palabras clave
mycobacterium avium mac cns hiv case report intracranial cns macResumen
Background Mycobacterium avium complex (MAC) is an uncommon clinical pathogen, especially in the central nervous system (CNS), and carries a poor prognosis.
MAC infections commonly present as immune reconstitution disease (IRD) in HIV patients.
Herein, we report a case of intracranial infection caused by MAC in an AIDS patient without disseminated MAC (DMAC) and immune reconstitution inflammatory syndrome (IRIS).
Case presentation A 31-year-old HIV-positive male presented us with progressively worsening CNS symptoms, and neuroimaging revealed ring-enhancing lesions.
The intracranial lesions worsened after the empirical therapy for toxoplasma encephalitis and fungal infection.
Due to the rapid progression of the disease, the patient died.
Mycobacterium avium was the only pathogen in brain tissue after cultures and molecular biology tests.
Conclusion MAC infection in CNS is challenging to diagnose in HIV patients.
Our findings emphasize that obtaining tissue samples and applying molecular biology methods is essential to help diagnose the patient as soon as possible to receive adequate treatment.
Wang, Mengyan,Cui, Yahui,Shi, Jinchuan,Yan, Jun, 2024, Difficulty in diagnosing intracranial infection caused by Mycobacterium avium in an AIDS patient: case report and review of the literature, BioMed Central
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