detalle del documento
IDENTIFICACIÓN
oai:pubmedcentral.nih.gov:1100...
Tema
Case ReportAutor
Klein, Benjamin Treudler, ReginaLangue
enEditor
Dustri-Verlag Dr. Karl Feistle
Categoría
Allergologie Select
Año
2024
fecha de cotización
10/6/2024
Palabras clave
eosinophilic dupilumabResumen
Abstract.
Background: Eosinophilic esophagitis (EoE) is an inflammatory disease of the esophagus that belongs to the spectrum of Th2-mediated diseases.
It is often associated with atopic comorbidities such as allergic asthma (AA) and poses a therapeutic challenge.
Case report: We report on a 43-year-old patient with EoE and AA who did not show sufficient therapeutic control despite standard therapy.
We started treatment with dupilumab, whereupon both EoE and AA rapidly improved and complete symptom resolution could be documented.
The response to dupilumab was assessed by laboratory monitoring and gastroscopy, which showed a reduction of markers of type II inflammation and eosinophilic infiltrates in the esophagus.
Summary: Our report emphasizes the effective and safe use of dupilumab as a treatment option for EoE with concomitant beneficial effects on AA.
Klein, Benjamin,Treudler, Regina, 2024, Rapid response to dupilumab in an adult patient with eosinophilic esophagitis and allergic asthma, Dustri-Verlag Dr. Karl Feistle
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