Détail du document
Identifiant
doi:10.1186/s12866-024-03379-1...
Auteur
Ying, Xue Xu, Gufeng Wang, Huiyun Wang, YueLangue
enEditeur
BioMed Central
Catégorie
Mycology
Année
2024
Date de référencement
17/07/2024
Mots clés
microbiome endometrial hyperplasia uterus 16s rdna ... ... ... microbiome hyperplasiaRésumé
Background Endometrial hyperplasia (EH) is a precursor to endometrial cancer, and the role of the microbiome in its development is unclear.
Results The present study investigated the uterine microbiome in patients with benign uterine conditions and endometrial hyperplasia.
A significant structural shift in the uterine microbiome of patients with endometrial hyperplasia compared to those with benign conditions was found.
Delftia , Serratia and Stenotrophomonas were significantly enriched in endometrial hyperplasia samples and associated with the presence of endometrial hyperplasia.
Conclusions The novel finding suggested that increased abundance of Delftia , Serratia and Stenotrophomonas is associated with the presence of endometrial hyperplasia.
Further investigation is needed to determine the value of these microbes as biomarkers for endometrial hyperplasia.
Ying, Xue,Xu, Gufeng,Wang, Huiyun,Wang, Yue, 2024, An altered uterine microbiota with endometrial hyperplasia, BioMed Central
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