Détail du document
Identifiant

oai:pubmedcentral.nih.gov:1057...

Sujet
Review
Auteur
Jang, Jae-Hyuk Kim, Joo-Hee Park, Hae-Sim
Langue
en
Editeur

The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease

Catégorie

Allergy, Asthma & Immunology Research

Année

2023

Date de référencement

16/10/2023

Mots clés
respiratory iggscd chronic
Métrique

Résumé

Primary immunodeficiency diseases (PIDs) are uncommon in adults; however, immunoglobulin G subclass deficiency (IGGSCD) is often found in a subset of adult patients with chronic respiratory diseases.

As quantitative laboratory tests are used to diagnose IGGSCD, the clinical significance of IGGSCD remains controversial.

However, respiratory infection is a common presenting feature of IGGSCD, and respiratory complications are responsible for subsequent morbidities, such as severe asthma, bronchiectasis, chronic obstructive airway diseases, and mortality.

This review summarizes the current epidemiological data for PIDs, focusing on IGGSCD in the adult population.

In addition, the investigation, treatment, and management strategies are detailed, including distinct issues faced by patients with chronic airway disease and their physicians in the proper diagnosis and treatment of IGGSCD.

Jang, Jae-Hyuk,Kim, Joo-Hee,Park, Hae-Sim, 2023, Current Issues in the Management of IgG Subclass Deficiencies in Adults With Chronic Respiratory Diseases, The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease

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