Détail du document
Identifiant
oai:HAL:hal-04210386v1
Sujet
45 References 3 Tables 4 Figures P... 45 References 3 Tables 4 Figures Parkinson's disease gait disorders falls exergaming rehabilitation [SHS]Humanities and Social Science...Auteur
Nuic, Dijana van de Weijer, Sjors Cherif, Saoussen Skrzatek, Anna Zeeboer, Eline Olivier, Claire Corvol, Jean‐christophe Foulon, Pierre Pastor, Jénica, Z Mercier, Gregoire Lau, Brian Bloem, Bastiaan de Vries, Nienke, M Welter, Marie‐laureLangue
enEditeur
HAL CCSD
Catégorie
CNRS - Centre national de la recherche scientifique
Année
2023
Date de référencement
15/12/2023
Mots clés
difference randomized control = 0 duration disorders exergaming swst change home‐based disease parkinson gait balance active trainingRésumé
Abstract Background Exergaming has been proposed to improve gait and balance disorders in Parkinson's disease (PD) patients.
We aimed to assess the efficacy of a home‐based, tailored, exergaming training system designed for PD patients with dopa‐resistant gait and/or balance disorders in a controlled randomized trial.
Methods We recruited PD patients with dopa‐resistant gait and/or balance disorders.
Patients were randomly assigned (1:1 ratio) to receive 18 training sessions at home by playing a tailored exergame with full‐body movements using a motion capture system (Active group), or by playing the same game with the computer's keyboard (Control group).
The primary endpoint was the between‐group difference in the Stand‐Walk‐Sit Test (SWST) duration change after training.
Secondary outcomes included parkinsonian clinical scales, gait recordings, and safety.
Results Fifty PD patients were enrolled and randomized.
After training, no significant difference in SWST change was found between groups (mean change SWST duration [SD] −3.71 [18.06] s after Active versus −0.71 [3.41] s after Control training, p = 0.61).
Some 32% of patients in the Active and 8% in the Control group were considered responders to the training program (e.g., SWST duration change ≥2 s, p = 0.03).
The clinical severity of gait and balance disorders also significantly decreased after Active training, with a between‐group difference in favor of the Active training ( p = 0.0082).
Home‐based training induced no serious adverse events.
Conclusions Home‐based training using a tailored exergame can be performed safely by PD patients and could improve gait and balance disorders.
Future research is needed to investigate the potential of exergaming.
Nuic, Dijana,van de Weijer, Sjors,Cherif, Saoussen,Skrzatek, Anna,Zeeboer, Eline,Olivier, Claire,Corvol, Jean‐christophe,Foulon, Pierre,Pastor, Jénica, Z,Mercier, Gregoire,Lau, Brian,Bloem, Bastiaan,de Vries, Nienke, M,Welter, Marie‐laure, 2023, Home‐based exergaming to treat gait and balance disorders in patients with Parkinson's disease: A phase II randomized controlled trial, HAL CCSD
SliM-LLM: Salience-Driven Mixed-Precision Quantization for Large Language Models
methods salience efficiency quantization language slim-llm llms
Prediction Models for Suicide Attempts among Adolescents Using Machine Learning Techniques
using data ml prediction 0 suicide adolescents
