Tough surroundings make cancer tougher for immune cells to fight

Document detail
ID

doi:10.1038/s42003-023-05756-4...

Author
Joseph, Joel P.
Langue
en
Editor

Nature

Category

Life Sciences

Year

2024

listing date

1/10/2024

Keywords
cells cancer
Metrics

Abstract

The physical properties of the cells and proteins surrounding a tumor play a crucial role in determining the spread of the cancer.

How they change cancer cells to suppress the immune response against them is an interesting question addressed in a recent study from Liu et al., which describes how increased stiffness of the tissue around the tumor decreases the amount of a protein—cyclic GMP-AMP synthase—in cancer cells, ultimately blocking the immune response to cancer.

Joseph, Joel P., 2024, Tough surroundings make cancer tougher for immune cells to fight, Nature

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springer

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