Document detail
ID

doi:10.1186/s12879-023-08554-9...

Author
Yu, Lele Zhang, Binhai Shi, Jinchuan Wang, Mengyan Wan, Hu
Langue
en
Editor

BioMed Central

Category

Medicine & Public Health

Year

2023

listing date

8/30/2023

Keywords
... ... hiv case report ngs infection destruction
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Abstract

Introduction Talaromycosis is a common invasive fungal disease in patients with HIV.

However, its association with bone destruction is unusual in AIDS patients with talaromycosis.

Case Presentation This report covers the case of a 38-year-old male AIDS patient coinfected with Talaromyces marneffei and Salmonella .

The case, which involved bone destruction, was identified via metagenomic next-generation sequencing (mNGS).

Following treatment with a combination of amphotericin B and piperacillin-tazobactam, the patient’s elbow motion noticeably improved.

Imaging findings revealed that the progression of bony destruction had halted.

Conclusion Bone damage due to Talaromyces marneffei infection is infrequent in HIV-positive patients.

Therefore, healthcare professionals must be vigilant for potential bone lesions associated with this type of infection.

Prompt diagnosis and antimicrobial treatment are crucial.

Yu, Lele,Zhang, Binhai,Shi, Jinchuan,Wang, Mengyan,Wan, Hu, 2023, Osteoarticular infection caused by Talaromyces Marneffei and Salmonella in a person living with HIV: a case report, BioMed Central

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