Document detail
ID
doi:10.1186/s12894-024-01416-9...
Author
Collingridge, Adam O’Callaghan, MichaelLangue
enEditor
BioMed Central
Category
Urology
Year
2024
listing date
2/7/2024
Keywords
calcium oxalate stone fluid intake nephrolithiasis randomized controlled trial urine volume study water stoneAbstract
Kidney stones, a persistent urological condition, continue to affect people globally.
In this critical review, we examine the work of Borghi et al. who evaluated patients with idiopathic stone formation and randomised 99 patients to increased water intake (≥ 2 L/day) and 100 patients to usual care in a 5-year randomized controlled trial.
The study examined baseline urine volume in individuals with idiopathic calcium stones, recurrence rates, and relevant biochemical factors.
The study found reduced recurrence rate (12.1% vs. 27% (p = 0.008)), and time to recurrence with increased water intake (38.7 ± 13.2 months) vs. (25 ± 16.4 months) ( p = 0.016).
These findings inform clinical practice, contributing to the guideline recommendations that kidney stone patients should aim for fluid intake of at least 2.5 L per day to prevent stone recurrence.
Collingridge, Adam,O’Callaghan, Michael, 2024, Seminal papers in urology: urinary volume, water and recurrences in idiopathic calcium nephrolithiasis: a 5-year randomized prospective study, BioMed Central
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