Document detail
ID

oai:pubmedcentral.nih.gov:1179...

Topic
Mini-Review
Author
Choi, Eung Ho
Langue
en
Editor

The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease

Category

Allergy, Asthma & Immunology Research

Year

2025

listing date

2/12/2025

Keywords
skin neonates infants barrier
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Abstract

This review focuses on the skin barrier function in neonates and infants, emphasizing the structural and functional differences compared to adult skin.

Neonatal and infant skin is thinner, more permeable, and less developed, which makes it more vulnerable to irritants, infections, and dehydration.

Additionally, the critical role of skin pH in maintaining barrier function is discussed, noting significant changes in pH levels during early life.

This review also examines the relationship between the onset of atopic dermatitis and skin barrier function, underscoring the importance of maintaining skin barrier integrity from birth to reduce the risk of atopic diseases.

Finally, recommendations are offered for skincare practices in neonates and infants, emphasizing the use of mild, fragrance-free products and the importance of tailoring skincare regimens to meet the specific needs of each neonate or infant.

Choi, Eung Ho, 2025, Skin Barrier Function in Neonates and Infants, The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease

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