Document detail
ID

oai:pubmedcentral.nih.gov:8750...

Topic
Clinical Investigations
Author
Zoethout, Aleksandra C. Ketting, Shirley Zeebregts, Clark J. Apostolou, Dimitri Mees, Barend M.E. Berg, Patrick Beyrouti, Hazem El De Vries, Jean-Paul P.M. Torella, Francesco Migliari, Mattia Silingardi, Roberto Reijnen, Michel M.P.J.
Langue
en
Editor

SAGE Publications

Category

PMC full-text journals

Year

2021

listing date

10/11/2022

Keywords
patient reinterventions endovascular mortality evar study treatment follow-up endoleaks aneurysm iii evas freedom
Metrics

Abstract

INTRODUCTION: Type III endoleaks post-endovascular aortic aneurysm repair (EVAR) warrant treatment because they increase pressure within the aneurysm sac leading to increased rupture risk.

The treatment may be difficult with regular endovascular devices.

Endovascular aneurysm sealing (EVAS) might provide a treatment option for type III endoleaks, especially if located near the flow divider.

This study aims to analyze clinical outcomes of EVAS for type III endoleaks after EVAR.

METHODS: This is an international, retrospective, observational cohort study including data from 8 European institutions.

RESULTS: A total of 20 patients were identified of which 80% had a type IIIb endoleak and the remainder (20%) a type IIIa endoleak.

The median time between EVAR and EVAS was 49.5 months (28.5–89).

Mean AAA diameter prior to EVAS revision was 76.6±19.9 mm.

Technical success was achieved in 95%, 1 patient had technical failure due to a postoperative myocardial infarction resulting in death.

Mean follow-up was 22.8±15.2 months.

During follow-up 1 patient had a type Ia endoleak, and 1 patient had a new type IIIa endoleak at an untreated location.

There were 5 patients with aneurysm growth.

Five patients underwent AAA-related reinterventions indications being: growth with type II endoleak (n=3), type Ia endoleak (n=1), and iliac aneurysm (n=1).

At 1-year follow-up, the freedom from clinical failure was 77.5%, freedom from all-cause mortality 94.7%, freedom from aneurysm-related mortality 95%, and freedom from aneurysm-related reinterventions 93.8%.

CONCLUSION: The EVAS relining can be safely performed to treat type III endoleaks with an acceptable technical success rate, a low 30-day mortality rate and no secondary ruptures at short-term follow-up.

The relatively low clinical success rates, related to reinterventions and AAA enlargement, highlight the need for prolonged follow-up.

Zoethout, Aleksandra C.,Ketting, Shirley,Zeebregts, Clark J.,Apostolou, Dimitri,Mees, Barend M.E.,Berg, Patrick,Beyrouti, Hazem El,De Vries, Jean-Paul P.M.,Torella, Francesco,Migliari, Mattia,Silingardi, Roberto,Reijnen, Michel M.P.J., 2021, An International, Multicenter Retrospective Observational Study to Assess Technical Success and Clinical Outcomes of Patients Treated with an Endovascular Aneurysm Sealing Device for Type III Endoleak, SAGE Publications

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