Document detail
ID
doi:10.1038/s41420-023-01430-0...
Author
Liang, Jiaming Liao, Yihao Wang, Pu Yang, Kun Wang, Youzhi Wang, Keke Zhong, Boqiang Zhou, Diansheng Cao, Qian Li, Junbo Zhao, Yang Jiang, NingLangue
enEditor
Nature
Category
Life Sciences
Year
2023
listing date
4/19/2023
Keywords
cancer ferroptosisAbstract
Prostate cancer is a major disease that threatens men’s health.
Its rapid progression, easy metastasis, and late castration resistance have brought obstacles to treatment.
It is necessary to find new effective anticancer methods.
Ferroptosis is a novel iron-dependent programmed cell death that plays a role in various cancers.
Understanding how ferroptosis is regulated in prostate cancer will help us to use it as a new way to kill cancer cells.
In this review, we summarize the regulation and role of ferroptosis in prostate cancer and the relationship with AR from the perspective of metabolism and molecular pathways.
We also discuss the feasibility of ferroptosis in prostate cancer treatment and describe current limitations and prospects, providing a reference for future research and clinical application of ferroptosis.
Liang, Jiaming,Liao, Yihao,Wang, Pu,Yang, Kun,Wang, Youzhi,Wang, Keke,Zhong, Boqiang,Zhou, Diansheng,Cao, Qian,Li, Junbo,Zhao, Yang,Jiang, Ning, 2023, Ferroptosis landscape in prostate cancer from molecular and metabolic perspective, Nature
