Document detail
ID
doi:10.1007/s00428-024-03744-5...
Author
Longerich, T. Stenzinger, A. Schirmacher, P.Langue
enEditor
Springer
Category
Medicine & Public Health
Year
2024
listing date
3/6/2024
Keywords
hepatobiliary molecular diagnostics cancer pancreas personalized medicineAbstract
Neoplasias of the hepatopancreatobiliary tract are growing in numbers, have the poorest prognosis of all major cancer entities, and thus represent a rising clinical problem.
Their molecular diagnostic has dramatically improved, contributing to tumor subtyping, definition of malignancy, and uncovering cases with hereditary predisposition.
Most of all, predictive molecular testing allows to identify cases amenable to treatment with the rising number of approved targeted drugs, immune-oncological treatment, and clinical trials.
In this review, the current state of molecular testing and its contribution to clinical decision-making are outlined.
Longerich, T.,Stenzinger, A.,Schirmacher, P., 2024, Molecular diagnostics of hepatobiliary and pancreatic neoplasias, Springer
Projection-Specific Heterogeneity of the Axon Initial Segment of Pyramidal Neurons in the Prelimbic Cortex
heterogeneity projection-specific
