Document detail
ID
doi:10.1186/s12902-023-01488-y...
Author
Pravin, R. R. Kan, Sheau Yun Soh, Ser Yee Chan, Daniel Farhad Vasanwala, RashidaLangue
enEditor
BioMed Central
Category
Medicine & Public Health
Year
2023
listing date
11/8/2023
Keywords
hypothyroidism thyroid growth puberty clinical childrenAbstract
Primary acquired hypothyroidism in children manifests with a myriad of clinical presentations.
Clinical features can be insidious in nature, often under the guise of non-specific presentations to other subspecialties prior to referral to the endocrinologist.
Growth failure is a hallmark feature in these children alongside their presenting clinical symptomology which needs to be identified through detailed history, physical examination and analysis of the growth charts.
In this case series, we discuss 5 atypical presentations of acquired primary hypothyroidism with multisystemic involvement, including musculoskeletal, hepatobiliary, gynaecological and haematological manifestations.
This is of importance as untreated hypothyroidism leads to fatigue, decreased physical activity, suboptimal height gain, disordered puberty and poor neurocognitive development in children with long term detrimental outcomes.
Pravin, R. R.,Kan, Sheau Yun,Soh, Ser Yee,Chan, Daniel,Farhad Vasanwala, Rashida, 2023, Atypical presentations of primary acquired hypothyroidism – a case series, BioMed Central
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