Document detail
ID
oai:pubmedcentral.nih.gov:1036...
Topic
ReviewAuthor
Abboud, Tammam Rohde, Veit Mielke, DorotheeLangue
enEditor
BioMed Central
Category
BMC Neuroscience
Year
2023
listing date
12/11/2023
Keywords
protein s100bAbstract
Prognosticating the clinical outcome of neurological diseases is essential to guide treatment and facilitate decision-making.
It usually depends on clinical and radiological findings.
Biomarkers have been suggested to support this process, as they are deemed objective measures and can express the extent of tissue damage or reflect the degree of inflammation.
Some of them are specific, and some are not.
Few of them, however, reached the stage of daily application in clinical practice.
This mini review covers available applications of the S100B protein in prognosticating clinical outcome in patients with various neurological disorders, particularly in those with traumatic brain injury, spontaneous subarachnoid hemorrhage and ischemic stroke.
The aim is to provide an understandable picture of the clinical use of the S100B protein and give a brief overview of the current limitations that require future solutions.
Abboud, Tammam,Rohde, Veit,Mielke, Dorothee, 2023, Mini review: Current status and perspective of S100B protein as a biomarker in daily clinical practice for diagnosis and prognosticating of clinical outcome in patients with neurological diseases with focus on acute brain injury, BioMed Central
