Document detail
ID
oai:pubmedcentral.nih.gov:1011...
Topic
PerspectiveAuthor
Fittall, Matthew Liu, Justin Platt, James Ionescu, Maria Sheehan, Remarez Johal, Sukhmunni Mew, Rosie Clark, James Watts, Izzy Tripathy, Arvind Little, Martin Patel, Grisma Panneerselvam, Hari Appanna, Nathan Burke, Emma McKenzie, Hayley Tilby, Michael Khan, Sam Lee, Lennard Y. W.Langue
enEditor
Nature Publishing Group UK
Category
British Journal of Cancer
Year
2023
listing date
12/14/2023
Keywords
hyper-accelerated cancerAbstract
The COVID-19 pandemic has led to a range of novel and adaptive research designs.
In this perspective, we use our experience coordinating the National COVID Cancer Antibody Survey to demonstrate how a balance between speed and integrity can be achieved within a hyper-accelerated study design.
Using the COVID-19 pandemic as an example, we show this approach is necessary in the face of uncertain and evolving situations wherein reliable information is needed in a timely fashion to guide policy.
We identify streamlined participant involvement, healthcare systems integration, data architecture and real-world real-time analytics as key areas that differentiate this design from traditional cancer trials, and enable rapid results.
Caution needs to be taken to avoid the exclusion of patient subgroups without digital access or literacy.
We summarise the merits and defining features of hyper-accelerated cancer studies.
Fittall, Matthew,Liu, Justin,Platt, James,Ionescu, Maria,Sheehan, Remarez,Johal, Sukhmunni,Mew, Rosie,Clark, James,Watts, Izzy,Tripathy, Arvind,Little, Martin,Patel, Grisma,Panneerselvam, Hari,Appanna, Nathan,Burke, Emma,McKenzie, Hayley,Tilby, Michael,Khan, Sam,Lee, Lennard Y. W., 2023, The National COVID Cancer Antibody Survey: a hyper-accelerated study proof of principle for cancer research, Nature Publishing Group UK
