Document detail
ID
oai:HAL:hal-04053625v1
Topic
Parkinson's Disease Dynamical system Electroencephalogram Sparse features Machine Learning [INFO.INFO-AU]Computer Science [cs... [INFO.INFO-AI]Computer Science [cs... [INFO.INFO-BI]Computer Science [cs...Author
Meghnoudj, Houssem Robu, Bogdan Alamir, MazenLangue
enEditor
HAL CCSD
Category
CNRS - Centre national de la recherche scientifique
Year
2023
listing date
9/29/2023
Keywords
using parkinson [info science accuracy disease featuresAbstract
Under review, (18 pages, 13 figures); In this study we focus on the diagnosis of Parkinson's Disease (PD) based on electroencephalogram (EEG) signals.
We propose a new approach inspired by the functioning of the brain that uses the dynamics, frequency and temporal content of EEGs to extract new demarcating features of the disease.
The method was evaluated on a publicly available dataset containing EEG signals recorded during a 3-oddball auditory task involving N = 50 subjects, of whom 25 suffer from PD.
By extracting two features, and separating them with a straight line using a Linear Discriminant Analysis (LDA) classifier, we can separate the healthy from the unhealthy subjects with an accuracy of 90 % (p < 0.03) using a single channel.
By aggregating the information from three channels and making them vote, we obtain an accuracy of 94 %, a sensitivity of 96 % and a specificity of 92 %.
The evaluation was carried out using a nested Leave-One-Out cross-validation procedure, thus preventing data leakage problems and giving a less biased evaluation.
Several tests were carried out to assess the validity and robustness of our approach, including the test where we use only half the available data for training.
Under this constraint, the model achieves an accuracy of 83.8 %.
Meghnoudj, Houssem,Robu, Bogdan,Alamir, Mazen, 2023, Sparse Dynamical Features generation, application to Parkinson's Disease diagnosis, HAL CCSD
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