doi:10.1186/s13256-023-04127-1...
BioMed Central
Medicine & Public Health
2023
9/20/2023
Background Acrometastasis is an uncommon finding in non-small cell lung cancer and is usually a sign of multimetastatic disease.
Few case reports have suggested solitary digital metastasis as the single secondary lesion of oligometastatic non-small cell lung cancer.
Case presentation This case report describes an unusual presentation of a Kirsten rat sarcoma viral oncogene homolog-mutated lung adenocarcinoma with a solitary bone metastasis in the fourth finger medial phalanx, which was also the first sign of the disease, in a 63-year-old Caucasian female patient.
Digital surgical amputation was performed.
After histopathological confirmation and radiological exclusion of other secondary lesions, chemoimmunotherapy in a first-line setting was initiated.
A partial metabolic response in the primary lung lesion was observed after four cycles.
Maintenance therapy is currently being continued.
Conclusion Solitary digital metastasis is a rare finding in non-small cell lung cancer.
Further studies are needed to investigate the mechanisms behind this particular dissemination process.
Pușcașu, Alexandra-Ioana,Moinard-Butot, Fabien,Antoni, Delphine,Schott, Roland,Somme, Laura, 2023, Solitary acrometastasis of the phalanx as initial presentation of an oligometastatic Kirsten rat sarcoma viral oncogene homolog-mutated lung adenocarcinoma: a case report, BioMed Central