doi:10.1038/s42003-023-05756-4...
Nature
Life Sciences
2024
10.01.2024
The physical properties of the cells and proteins surrounding a tumor play a crucial role in determining the spread of the cancer.
How they change cancer cells to suppress the immune response against them is an interesting question addressed in a recent study from Liu et al., which describes how increased stiffness of the tissue around the tumor decreases the amount of a protein—cyclic GMP-AMP synthase—in cancer cells, ultimately blocking the immune response to cancer.
Joseph, Joel P., 2024, Tough surroundings make cancer tougher for immune cells to fight, Nature