Dokumentdetails
ID

doi:10.1186/s12957-023-03051-4...

Autor
Zhang, Nina Jin, Xiangshu Yang, Wen Gu, Chenglei Li, Li’an Xu, Jia Tang, Qiting Fan, Wensheng Meng, Yuanguang
Langue
en
Editor

BioMed Central

Kategorie

Medicine & Public Health

Jahr

2023

Auflistungsdatum

05.07.2023

Schlüsselwörter
cervical cancer arh lrh rrh vrh survival early-stage study cancer cervical 5-year os vrh hysterectomy radical rrh lrh arh survival
Metrisch

Zusammenfassung

Background This study compared the survival outcomes of abdominal radical hysterectomy (ARH) ( N  = 32), laparoscopic radical hysterectomy (LRH) ( N  = 61), robot-assisted radical hysterectomy (RRH) ( N  = 100) and vaginal radical hysterectomy (VRH) ( N  = 45) approaches for early-stage cervical cancer to identify the surgical approach that provides the best survival.

Methods Disease-free survival (DFS) and overall survival (OS) were calculated using the Kaplan–Meier method, and survival curves were compared using the log-rank test.

Results The volume of intraoperative blood loss was greater in the ARH group than in the LRH group, the RRH group or the VRH group [(712.50 ± 407.59) vs. (224.43 ± 191.89), (109.80 ± 92.98) and (216.67 ± 176.78) ml, respectively; P  < 0.001].

Total 5-year OS was significantly different among the four groups (ARH, 96.88%; LRH, 82.45%; RRH, 94.18%; VRH, 91.49%; P  = 0.015).

However, no significant difference in 5-year DFS was observed among the four groups (ARH, 96.88%; LRH, 81.99%; RRH, 91.38%; VRH, 87.27%; P  = 0.061).

Conclusion This retrospective study demonstrated that ARH and RRH achieved higher 5-year OS rates than LRH for early-stage cervical cancer.

Zhang, Nina,Jin, Xiangshu,Yang, Wen,Gu, Chenglei,Li, Li’an,Xu, Jia,Tang, Qiting,Fan, Wensheng,Meng, Yuanguang, 2023, Survival outcomes of abdominal radical hysterectomy, laparoscopic radical hysterectomy, robot-assisted radical hysterectomy and vaginal radical hysterectomy approaches for early-stage cervical cancer: a retrospective study, BioMed Central

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