Dokumentdetails
ID
doi:10.1186/s12894-023-01252-3...
Autor
Liao, Tuming Du, Wei Li, Xiongcai He, Shen Guan, Gangqiang Zhu, Herong Wu, JiaqiaoLangue
enEditor
BioMed Central
Kategorie
Urology
Jahr
2023
Auflistungsdatum
26.04.2023
Schlüsselwörter
recurrence metastasis dedifferentiated liposarcoma combined organ resection targeted therapy lps dedifferentiated tumors left surgical tumor rplps retroperitonealZusammenfassung
Background Retroperitoneal liposarcoma (RPLPS), a rare tumor, is often treated using surgical procedures as the first choice for treatment.
However, there is no consensus on the scope of surgical resection.
In addition, the treatment outcomes of conventional radiotherapy and chemotherapy have not been satisfactory, particularly for specific types of LPS, such as dedifferentiated LPS.
In this case study, we present a brief review of other cases of RPLPS, highlighting the selection of surgical scope for RPLPS and related adjuvant treatment for advanced RPLPS.
Case presentation A case study is reported regarding an extremely rare recurrent and metastatic retroperitoneal dedifferentiated LPS.
The primary RPLPS tumor, with a diameter of 20 cm and a weight of 2.5 kg, occupied the whole left abdomen and adhered to the left kidney.
A surgical tumor resection combined with a left nephrectomy is performed.
During the 6th -month postoperative follow-up examination, we observed the local recurrence of the tumor in the operation area, in addition to multiple metastatic tumors in both lungs.
Further, the prescribed 3-month targeted treatment with anlotinib significantly reduced the size of the metastatic pulmonary tumors.
However, the recurrent retroperitoneal tumors showed no significant change in size.
Eventually, we observed no substantial evidence of tumor progression, with the patient’s condition under control.
Conclusion The case demonstrated that the postoperative recurrence of widespread RPLPS required R0 resection to cure the disease, considering targeted therapy for advanced RPLPS control.
Liao, Tuming,Du, Wei,Li, Xiongcai,He, Shen,Guan, Gangqiang,Zhu, Herong,Wu, Jiaqiao, 2023, Recurrent metastatic retroperitoneal dedifferentiated liposarcoma: a case report and literature review, BioMed Central
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