Dokumentdetails
ID
oai:pubmedcentral.nih.gov:8751...
Thema
Original ArticlesAutor
Zahradnik, Eva Sander, Ingrid Kleinmüller, Olaf Lotz, Anne Liebers, Verena Janssen-Weets, Bente Kler, Stéphanie Hilger, Christiane Beine, Alexandra Hoffmeyer, Frank Nienhaus, Albert Raulf, MonikaLangue
enEditor
Oxford University Press
Kategorie
Annals of Work Exposures and Health
Jahr
2021
Auflistungsdatum
21.10.2023
Schlüsselwörter
β- -glucan significantly equ veterinary using animal exposure allergens endotoxin practices homesZusammenfassung
OBJECTIVES: In veterinary settings, high exposures to animal allergens and microbial agents can be expected.
However, occupational exposure levels are largely unknown.
The objective of this study was to estimate the allergen, endotoxin, and β-(1,3)-glucan concentrations in small animal practices and in the homes of practice employees.
METHODS: Dust samples were collected using electrostatic dust fall collectors in diverse rooms of 36 small animal practices, as well as in employees’ homes.
Major animal allergens (Fel d 1, Can f 1, Ory c 3, Cav p 1, Equ c 1, Bos d 2), domestic mite (DM) allergens, and β-(1,3)-glucan levels were measured using enzyme immunoassays.
Endotoxin was determined using the Limulus amoebocyte lysate assay.
Influences on exposure levels were analyzed using multilevel models.
RESULTS: The levels of Can f 1, Fel d 1, Ory c 3, and Cav p 1 were up to 30 times higher in practices compared with homes without animals, but significantly lower compared with the homes with the respective pet.
Although horses were not treated in the practices, Equ c 1 was found in 87.5% of samples, with the highest concentrations measured in changing rooms.
DM levels were significantly lower in practices than in all private homes, and endotoxin levels were similar to those in homes with pets.
In the practice itself, exposure levels were significantly influenced by animal presence, type of the room, and area per employee; whereas, room volume and diverse cleaning measures had mostly no effect.
CONCLUSIONS: Exposure to animal allergens is high in veterinary practices, but it does not reach levels of households with pets.
Domestic mite allergen and endotoxin exposure seem to be low for workers in veterinary practices.
The high Equ c 1 detection rate strongly indicates dispersal of allergens, most likely through clothing and hair.
Zahradnik, Eva,Sander, Ingrid,Kleinmüller, Olaf,Lotz, Anne,Liebers, Verena,Janssen-Weets, Bente,Kler, Stéphanie,Hilger, Christiane,Beine, Alexandra,Hoffmeyer, Frank,Nienhaus, Albert,Raulf, Monika, 2021, Animal Allergens, Endotoxin, and β-(1,3)-Glucan in Small Animal Practices: Exposure Levels at Work and in Homes of Veterinary Staff, Oxford University Press
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