detalle del documento
IDENTIFICACIÓN
doi:10.1038/s41420-024-01868-w...
Autor
Gao, Wei Liu, Ya-Fang Zhang, Yan-Xia Wang, Yan Jin, Yu-Qing Yuan, Hang Liang, Xiao-Yi Ji, Xin-Ying Jiang, Qi-Ying Wu, Dong-DongLangue
enEditor
Nature
Categoría
Life Sciences
Año
2024
fecha de cotización
13/3/2024
Palabras clave
signaling cancerResumen
For a long time, hydrogen sulfide (H_2S) has been considered a toxic compound, but recent studies have found that H_2S is the third gaseous signaling molecule which plays a vital role in physiological and pathological conditions.
Currently, a large number of studies have shown that H_2S mediates apoptosis through multiple signaling pathways to participate in cancer occurrence and development, for example, PI3K/Akt/mTOR and MAPK signaling pathways.
Therefore, the regulation of the production and metabolism of H_2S to mediate the apoptotic process of cancer cells may improve the effectiveness of cancer treatment.
In this review, the role and mechanism of H_2S in cancer cell apoptosis in mammals are summarized.
Gao, Wei,Liu, Ya-Fang,Zhang, Yan-Xia,Wang, Yan,Jin, Yu-Qing,Yuan, Hang,Liang, Xiao-Yi,Ji, Xin-Ying,Jiang, Qi-Ying,Wu, Dong-Dong, 2024, The potential role of hydrogen sulfide in cancer cell apoptosis, Nature
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