Psychosocial Factors Linked to Uncontrolled Infection and Mortality among People Living with HIV Who Use Substances: A Latent Class Analysis

Schmidt, Renae D.; Horigian, Viviana E.; Duan, Rui; Traynor, Sharleen T.; Davis, Carly A.; Gonzalez, Sophia T.; Forney, Derrick J.; Mandler, Raul; Rio, Carlos; Metsch, Lisa R.; Feaster, Daniel J.

doi:10.1007/s10461-024-04410-2

Psychosocial Factors Linked to Uncontrolled Infection and Mortality among People Living with HIV Who Use Substances: A Latent Class Analysis

detalle del documento

IDENTIFICACIÓN

doi:10.1007/s10461-024-04410-2...

Autor

Schmidt, Renae D. Horigian, Viviana E. Duan, Rui Traynor, Sharleen T. Davis, Carly A. Gonzalez, Sophia T. Forney, Derrick J. Mandler, Raul Rio, Carlos Metsch, Lisa R. Feaster, Daniel J.

Langue

Editor

Springer

Categoría

Medicine & Public Health

Año

2024

fecha de cotización

7/8/2024

Palabras clave

hiv substance use disorder mental health co-occurring conditions latent symptoms psychosocial

Métrico

Resumen

To determine whether endorsement patterns of psychosocial symptoms revealed distinct subgroups, or latent classes, of people living with HIV who use substances (PLWH-SU), and to assess whether these classes demonstrated differential health outcomes over time.

This study uses data from 801 PLWH-SU initially enrolled across 11 US hospitals during 2012–2014 and followed up in 2017.

Latent class analysis included 28 psychosocial items.

Regression analysis examined class membership as a predictor of viral suppression.

Survival analysis examined class as a predictor of all-cause mortality.

The selected model identified five unique classes.

Individuals in classes characterized by more severe and more numerous psychosocial symptoms at baseline had lower likelihoods of viral suppression and survival.

The study demonstrated the importance of considering patterns of overlapping psychosocial symptoms to identify subgroups of PLWH-SU and reveal their risks for adverse outcomes.

Integration of primary, mental health, and substance use care is essential to address the needs of this population.

Schmidt, Renae D.,Horigian, Viviana E.,Duan, Rui,Traynor, Sharleen T.,Davis, Carly A.,Gonzalez, Sophia T.,Forney, Derrick J.,Mandler, Raul,Rio, Carlos,Metsch, Lisa R.,Feaster, Daniel J., 2024, Psychosocial Factors Linked to Uncontrolled Infection and Mortality among People Living with HIV Who Use Substances: A Latent Class Analysis, Springer