detalle del documento
IDENTIFICACIÓN

oai:pubmedcentral.nih.gov:8800...

Tema
Major Articles and Commentaries
Autor
Ortiz, Justin R Yu, Stephen L Driscoll, Amanda J Williams, Sarah R Robertson, Joanie Hsu, Jui-Shan Chen, Wilbur H Biellik, Robin J Sow, Samba Kochhar, Sonali Neuzil, Kathleen M
Langue
en
Editor

Oxford University Press

Categoría

Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America

Año

2021

fecha de cotización

30/9/2022

Palabras clave
risk targeting capacity 0% vaccination country influenza pregnant <5 ≥65 women storage persons
Métrico

Resumen

BACKGROUND: Influenza vaccination is uncommon in low-resource settings.

We evaluated aspects of operational feasibility of influenza vaccination programs targeting risk groups in the World Health Organization (WHO) African (AFR) and South-East Asian (SEAR) Regions.

METHODS: We estimated routine immunization and influenza vaccination campaign doses, doses per vaccinator, and cold storage requirements for 1 simulated country in each region using evidence-based population distribution, vaccination schedule, and vaccine volumes.

Influenza vaccination targeted persons <5 years, pregnant women, persons with chronic diseases, persons ≥65 years, and healthcare workers (HCW).

For the AFR country, we compared vaccine volumes to actual storage capacities.

RESULTS: Targeting HCW had a small operational impact, and subsequent findings exclude this group.

During 3-month influenza vaccination campaigns, monthly doses delivered in the AFR country increased from 15.0% for ≥65 years to 93.1% for <5 years and in the SEAR country from 19.6% for pregnant women to 145.0% for persons with chronic diseases.

National-level cold storage capacity requirements increased in the AFR country from 4.1% for ≥65 years to 20.3% for <5 years and in the SEAR country from 3.9% for pregnant women to 28.8% for persons with chronic diseases.

Subnational-level cold storage capacity requirements increased in the AFR country from 5.9% for ≥65 years to 36.8% for <5 years and the SEAR country from 17.6% for pregnant women to 56.0% for persons with chronic diseases.

CONCLUSIONS: Influenza vaccination of most risk groups will require substantial increases in doses, doses per vaccinator, and cold storage capacity in countries where infrastructure and resources are limited.

Ortiz, Justin R,Yu, Stephen L,Driscoll, Amanda J,Williams, Sarah R,Robertson, Joanie,Hsu, Jui-Shan,Chen, Wilbur H,Biellik, Robin J,Sow, Samba,Kochhar, Sonali,Neuzil, Kathleen M, 2021, The Operational Feasibility of Vaccination Programs Targeting Influenza Risk Groups in the World Health Organization (WHO) African and South-East Asian Regions, Oxford University Press

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