Détail du document
Identifiant
oai:pubmedcentral.nih.gov:9627...
Sujet
ReviewsAuteur
Zheng, Li Guo, Yunlu Zhai, Xiaozhu Zhang, Yueman Chen, Weijie Zhu, Ziyu Xuan, Wei Li, PeiyingLangue
enEditeur
John Wiley and Sons Inc.
Catégorie
CNS Neuroscience & Therapeutics
Année
2022
Date de référencement
12/12/2022
Mots clés
novelRésumé
Brain perivascular macrophages (PVMs) are attracting increasing attention as this emerging cell population in the brain has multifaced roles in supporting the central nervous system structure, brain development, and maintaining physiological functions.
They also widely participate in neurological diseases such as neurodegeneration and ischemic stroke.
Moreover, PVMs have been reported to have both beneficial and detrimental effects under different pathological contexts.
Advanced research technologies allowed the further in‐depth study of PVMs and revealed novel concepts in their origins, differentiation, and regulatory mechanisms.
Deepened understanding of the roles of PVMs in different brain pathological conditions can reveal novel phenotypic changes and regulatory signaling, which might pave the way for the development of novel treatment strategies targeting PVMs.
Zheng, Li,Guo, Yunlu,Zhai, Xiaozhu,Zhang, Yueman,Chen, Weijie,Zhu, Ziyu,Xuan, Wei,Li, Peiying, 2022, Perivascular macrophages in the CNS: From health to neurovascular diseases, John Wiley and Sons Inc.
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