Détail du document
Identifiant
oai:arXiv.org:2405.17352
Sujet
Computer Science - Machine Learnin...Auteur
Karaman, Batuhan K. Sabuncu, Mert R.Catégorie
Computer Science
Année
2024
Date de référencement
29/05/2024
Mots clés
alzheimer model forecasting ad longitudinal patient disease dataRésumé
In this study, we employ a transformer encoder model to characterize the significance of longitudinal patient data for forecasting the progression of Alzheimer's Disease (AD).
Our model, Longitudinal Forecasting Model for Alzheimer's Disease (LongForMAD), harnesses the comprehensive temporal information embedded in sequences of patient visits that incorporate multimodal data, providing a deeper understanding of disease progression than can be drawn from single-visit data alone.
We present an empirical analysis across two patient groups-Cognitively Normal (CN) and Mild Cognitive Impairment (MCI)-over a span of five follow-up years.
Our findings reveal that models incorporating more extended patient histories can outperform those relying solely on present information, suggesting a deeper historical context is critical in enhancing predictive accuracy for future AD progression.
Our results support the incorporation of longitudinal data in clinical settings to enhance the early detection and monitoring of AD.
Our code is available at \url{https://github.com/batuhankmkaraman/LongForMAD}.
Karaman, Batuhan K.,Sabuncu, Mert R., 2024, Assessing the significance of longitudinal data in Alzheimer's Disease forecasting
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